Articles tagged "Liver transplantation"

2020 American Transplant Congress
Can Biliary Internal Stents Reduce Biliary Complications in Adult Liver Transplantation?
Y. Kwon¹, Y. S. Genyk¹, Y. Yoon²
¹Division of Hepatobiliary, Pancreas, and Abdominal Organ Transplant, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, ²Division of Hepatobiliary, Pancreas, and Abdominal Organ Transplant, Department of Surgery, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea, Republic of
*Purpose: Biliary complications remain a consistent cause of morbidity and mortality in liver transplant (LT) recipients and there is controversy as to whether the use…
2020 American Transplant Congress
Prognostic Index of Circulating Tumor Cells for Tumor Recurrence in Patients with Hepatocellular Carcinoma after Liver Transplantation
M. Chen¹, Z. Chen¹, X. Lin², W. Ju¹, X. He¹
¹Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Division of General Surgery, The Eastern Hospital of the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: Liver transplantation (LT) is an effective option for hepatocellular carcinoma (HCC) and end-stage liver cirrhosis. However, organ shortage and tumor recurrence are the main…
2020 American Transplant Congress
Post-Transplant Hepatic CHOP Expression Dictates Clinical Outcomes in Liver Transplantation
H. Hirao¹, T. Ito¹, K. Nakamura², S. Kageyama¹, K. Kadono¹, H. Kojima¹, K. J. Dery¹, S. Younan¹, R. W. Busuttil¹, F. M. Kaldas¹, J. W. Kupiec‐Weglinski¹
¹UCLA, Los Angeles, CA, ²Kyoto University, Kyoto, Japan
*Purpose: Endoplasmic reticulum (ER) stress plays a pivotal role in the mechanism of liver ischemia reperfusion injury (IRI). Although we and others have demonstrated the…
2020 American Transplant Congress
History of Coronary Artery Disease Predicts Inferior Survival in Liver Transplant Recipients of Advanced Age in a Large Multicenter U.S. Cohort
M. German¹, A. Hristov¹, A. Lee¹, F. Osman¹, A. Kwong², D. Devuni³, C. Wang⁴, J. Boike⁵, J. Jo⁵, L. VanWagner⁵, M. Serper⁶, R. Sharma⁷, E. Verna⁷, J. Shor³, A. Koteish⁸, G. Sehmbey⁹, A. Seetharam⁹, N. John², Y. Patel¹⁰, M. Kappus¹⁰, T. Couri¹¹, S. Paul¹¹, R. Salgia¹², Q. Nhu¹³, C. Frenette¹³, J. Lai⁴, A. Goel², E. Spengler¹
¹U of Wisconsin, Madison, WI, ²Stanford, Palo Alto, CA, ³U of Massachusetts, Worcester, MA, ⁴U of California, San Francisco, CA, ⁵Northwestern, Chicago, IL, ⁶U of Pennsylvania, Philadelphia, PA, ⁷Columbia, New York, NY, ⁸Florida Hospital, Orlando, FL, ⁹U of Arizona, Phoenix, AZ, ¹⁰Duke, Durham, NC, ¹¹U of Chicago, Chicago, IL, ¹²Henry Ford Hospital, Detroit, MI, ¹³Scripps, San Diego, CA
*Purpose: Coronary artery disease (CAD) is common in patients of advanced age and does not preclude liver transplantation (LT) if adequately treated. We aimed to…
2020 American Transplant Congress
The Inflammatory Response in the Context of Tissue Injury: Roles of Tyro3, Axl, and Mer (TAM) Receptors in Liver Ischemia/Reperfusion Injury
J. Zhang, M. Ni, D. Jin, H. Zhang, R. Busuttil, J. Kupiec-Weglinski, Y. Zhai
Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Although the inflammatory response in liver ischemia reperfusion injury has been studied extensively, how the context of tissue injury (presence of necrotic/apoptotic cells) regulates…
2020 American Transplant Congress
Implementing a Height Based Rule for Allocation of Pediatric Donor Livers to Adults – A Liver Simulated Allocation Model (LSAM) Study
J. Ge¹, W. L. Nicholas², S. Gentry², J. C. Lai¹
¹Medicine-Gastroenterology, University of California, San Francisco, San Francisco, CA, ²Mathematics, United States Naval Academy, Annapolis, MD
*Purpose: Candidate height contributes to transplant rate and waitlist (WL) mortality disparities seen amongst adult women liver transplant (LT) candidates. 72% of adult women on…
2020 American Transplant Congress
Post-Transplant Recurrence Following Yttrium-90 Treatment in Liver Transplant Recipients with Hepatocellular Carcinoma
O. Rizzo, T. Kitajima, M. Kavousi, S. Yeddula, M. Rizzari, K. Collins, A. Yoshida, M. S. Abouljoud, S. Nagai
Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI
*Purpose: Yttrium-90 microspheres radioembolization (Y90) has shown to be effective as a bridging therapy for patients with advanced hepatocellular carcinoma (HCC) while on waiting list…
2020 American Transplant Congress
Early versus Delayed Initiation of CMV Prophylaxis after Liver Transplantation
M. Magid, J. Byrns, J. Gommer, Z. Yang, M. Harris
Duke University Hospital, Durham, NC
*Purpose: To determine the incidence of CMV DNAemia in early (prior to post-op day 7) versus delayed prophylaxis in liver transplant recipients.*Methods: Retrospective, single-center study…
2020 American Transplant Congress
Novel Flow-Based Assay to Detect Allospecific T Cells in Transplantation Study
N. Tanimine¹, B. E. Burrel², J. Pardo², C. Rickert³, K. M. Lee³, K. Deng³, N. Feeney³, C. Leguern³, J. F. Markmann³
¹Department of Gastroenterological and Transplantation Surgery, Hiroshima University, Hiroshima, Japan, ²Immune Tolerance Network, Bethesda, MD, ³Department of Surgery, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA
*Purpose: Identifying and phenotyping donor-reactive T cells in recipients following transplantation may further the understanding of interactions between the recipient’s immune system and donor antigen.…
2020 American Transplant Congress
Hepatocellular Carcinoma Locoregional Therapy: A Comparison of Radiologic Treatment Response and Post-Transplant Pathology
A. J. Hargrove¹, T. Donovan², K. Fisher³, M. Goodenberger⁴, A. Langnas¹, S. Merani¹
¹Department of Surgery, Division of Transplant Surgery, University of Nebraska Medical Center, Omaha, NE, ²Department of Radiology, Division of Interventional Radiology, University of Nebraska Medical Center, Omaha, NE, ³Department of Pathology, University of Nebraska Medical Center, Omaha, NE, ⁴Department of Radiology, Division of Body Imaging, University of Nebraska Medical Center, Omaha, NE
*Purpose: Transplantation or resection is the only potentially curative treatment for Hepatocellular Carcinoma (HCC). Locoregional therapy (LRT) is used exclusively in non-transplant candidates or as…