Articles tagged "Liver transplantation"

2020 American Transplant Congress
CEACAM1 / ASK1 / p38 Signaling Axis Alleviates Peri-Transplant Liver Injury: From Mouse-to-Human
H. Hirao¹, K. Nakamura², S. Kageyama¹, T. Ito¹, K. Kadono¹, H. Kojima¹, K. J. Dery¹, S. Younan¹, R. W. Busuttil¹, F. M. Kaldas¹, J. Kupiec-Weglinski¹
¹UCLA, Los Angeles, CA, ²Kyoto University, Kyoto, Japan
*Purpose: Although CEACAM1 (CM1; carcinoembryonic antigen-related cell adhesion molecule 1; CD66a) regulates hepatic metabolic homeostasis, its role in orthotopic liver transplantation (OLT) remains unknown. A…
2020 American Transplant Congress
Induction Immunosuppression with Thymoglobulin May Improve Graft Outcomes without Increasing a Risk for Infection in Patients Undergoing Liver Transplantation Alone
M. Henry¹, T. Kitajima², J. Konel¹, S. Yeddula², M. Rizzari², K. Collins², D. Moonka², A. Yoshida², M. Abouljoud², S. Nagai³
¹Wayne State University School of Medicine, Detroit, MI, ²Henry Ford Hospital, Detroit, MI, ³Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI
*Purpose: Immunosuppression protocols for liver transplant (LT) vary between institutions and roles of induction immunosuppression in LT remain controversial. The aim of this study was…
2020 American Transplant Congress
Development of Novel Multivariable Logistic Regression Model for Predicting Graft Failure within 2 Weeks and 4 Weeks after Liver Transplantation Using Post-Transplantation Laboratory Values
J. Kwon, S. Kim, G. Choi, J. Joh, J. Park, J. Rhu, K. Kim, O. Lee, M. Lim, E. Jeong, J. Yang
Transplantation, Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: This study designed a prediction model for graft failure after liver transplantation.*Methods: Multivariable logistic regression including aspartate aminotransferase (AST), total bilirubin (TB), and international…
2020 American Transplant Congress
Development of Recommendations for Liver Transplant Anesthesia Teams Using a Modified Delphi Process
C. Crouch, A. Hendrickse, S. Mandell
Department of Anesthesiology, University of Colorado, Aurora, CO
*Purpose: We utilized a modified Delphi technique to develop recommendations to guide service responsibilities for liver transplant anesthesia teams (LTATs).*Methods: The Society for the Advancement…
2020 American Transplant Congress
The Link between Waitlist Mortality and Access to Transplant, an Imaginative Reality
R. Batra¹, D. Mulligan¹, D. Haakinson¹, S. Noreen², D. Stewart², G. Gan³, Y. Deng³, S. Kulkarni¹
¹Surgery, Yale University School of Medicine, New Haven, CT, ²UNOS, Richmond, VA, ³Yale University, New Haven, CT
*Purpose: Liver transplant waitlist mortality due to inadequate access to livers is the Achilles heel in liver transplantation in United States. This remains amongst the…
2020 American Transplant Congress
The Impact of Initial Alpha-Fetoprotein >100 but <1,000 ng/mL and Pre-Transplant alpha-Fetoprotein Reduction on Outcomes after Liver Transplant in Patients with Hepatocellular Carcinoma
M. L. Goldman¹, K. Zhou², J. L. Dodge¹, F. Yao¹, N. Mehta¹
¹Department of Medicine, UCSF, San Francisco, CA, ²Department of Medicine, USC, Los Angeles, CA
*Purpose: Under current UNOS policy, hepatocellular carcinoma (HCC) patients with alpha-fetoprotein (AFP) >1,000 ng/mL are required to show a reduction in AFP to 100 but
2020 American Transplant Congress
Opioid Prescription Pattern and Risk Factors Associated with Opioid Use after Living Donor Hepatectomy in the US
M. Nguyen¹, L. Vest², Z. Zhang², V. Whittaker³, M. Schnitzler¹, D. Axelrod⁴, H. Randall¹, C. Varma¹, J. Snyder⁵, B. Kasiske⁵, D. Segev⁶, M. McAdams Demarco⁷, G. Hess⁸, K. Lentine²
¹Department of Surgery, Saint Louis University, Saint Louis, MO, ²Department of Medicine, Saint Louis University, Saint Louis, MO, ³Department of Surgery, New York Medical College, New York, NY, ⁴Department of Surgery, University of Iowa, Iowa City, IA, ⁵SRTR, Minneapolis, MN, ⁶Department of Surgery, Johns Hopkins University, Baltimore, MD, ⁷Johns Hopkins University, Baltimore, MD, ⁸Drexel University, Philadelphia, PA
*Purpose: Opioids are the cornerstone of acute pain management after living donor hepatectomy. Their misuse poses the danger of chronic abuse. How this affects living…
2020 American Transplant Congress
Metabolism Reprogramming During Conventional versus Ischemia-Free Liver Transplantation
Z. Guo¹, Z. Zhang¹, N. Gao¹, H. Zhang², X. He¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Sun Yat-sen University, Guangzhou, China
*Purpose: Our group has developed a novel transplant procedure called ischemia-free liver transplantation (IFLT), during which the liver can be procured, preserved and implanted without…
2020 American Transplant Congress
Sparing the Nephron in Liver Transplant Recipients with Antithymocyte Bridging: A Four Year Experience
N. Wilson, H. Kuzaro, N. Parrish, S. A. Shah, N. Anwar, R. R. Alloway, S. Tremblay, T. E. Kaiser
U Cincinnati, Cincinnati, OH
*Purpose: Renal function decline after liver transplant (LT) remains a significant issue. Using antithymocyte globulin (rATG) to delay tacrolimus (TAC) initiation may impact renal deterioration;…
2020 American Transplant Congress
A Liver Transplant Candidate with Above Average Conscientiousness is More Likely to Receive a Liver Transplant
O. Siddiqui¹, J. Lai², D. Peipert¹, T. Kaundinya¹, A. Daud¹, A. Hall¹, D. Ganger¹, R. Wong², C. Loftus¹, D. Mroczek¹, D. Ladner¹
¹Northwestern University, Chicago, IL, ²UCSF, San Francisco, CA
*Purpose: Liver transplant (LT) candidates are currently assessed in terms of their physical, social and mental capacity to take care of themselves and their grafts.…