Articles tagged "Liver transplantation"

2020 American Transplant Congress
Humanized Mouse Reveals the Cytoprotective Function of Hepatocyte RXFP1 in Liver Transplant Recipients
H. Kojima¹, S. Kageyama¹, K. Kadono¹, H. Hirao¹, K. J. Dery¹, T. Ito¹, G. Sugahara², Y. Ishida², T. Saito², F. M. Kaldas¹, R. W. Busuttil¹, J. W. Kupiec-Weglinski¹
¹Surgery, The Dumont-UCLA Transplantation Center, Los Angeles, CA, ²Division of Gastrointestinal and Liver Disease, Keck School of Medicine, USC, Los Angeles, CA
*Purpose: RXFP1 (RLX family peptide receptor 1) is a cognate receptor for relaxin (RLX), an insulin-like growth factor, with vasoactive/remodeling properties. We have documented cytoprotective…
2020 American Transplant Congress
Results of a Prospective Pilot Program for Transplantation of Patients with Alcohol-Related Liver Disease and Less Than 6 Months Abstinence
J. Quance, L. Carrique, I. Sales, L. Lilly, M. Bhat, Z. Galvin, A. Tan, S. Abbey, J. Lynch, N. Selzner
Multiorgan Transplant Institute, University of Toronto, Toronto, ON, Canada
*Purpose: In Canada, 6 months of abstinence for those with alcohol-associated liver disease (ALD) is typically required prior to being listed for liver transplantation (LT).This…
2020 American Transplant Congress
Outcomes in Liver Transplantation with Use of Granulocyte-Colony Stimulating Factor
K. Schnelle, A. Leino, M. Chunduru, L. Von Stein, O. Witkowsky
The Ohio State Wexner Medical Center, Columbus, OH
*Purpose: Questions remain if treatment with a granulocyte-colony stimulating factor (G-CSF) impacts clinical outcomes after liver transplant. The purpose of this study was to compare…
2020 American Transplant Congress
Taking Liver Transplant to “The Friendly Skies”: A Novel Pilot Program Using Commercial Flights and Ride-Sharing Apps to Minimize Dry-Run Expenses and Expand Potential Donors
G. J. McKenna, N. Onaca, H. Fernandez, E. Martinez, A. Gupta, A. Wall, J. Bayer, R. Ruiz, G. Testa
Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX
*Purpose: Growth in liver transplantation means using marginal/DCD donors, however these often fail to yield a suitable organ. Organ procurement can require travelling significant distances,…
2020 American Transplant Congress
Multimodal Strategy for Hepatocellular Carcinoma in the Elderly: To Transplant or Not to Transplant
M. Najjar¹, O. Perez¹, J. Zou¹, S. Sun¹, K. Bruestle¹, P. Jiang¹, E. Verna¹, E. Zheng¹, Y. Saenger¹, A. Mathur¹, A. Griesemer¹, B. Samstein², T. Kato¹, K. Halazun², J. Emond¹
¹Columbia University Irving Medical Center, New York, NY, ²Weill Cornell Medicine, New York, NY
*Purpose: Liver transplantation LT for HCC is curative but entails increased risk and is limited by organ scarcity. Alternative approaches such as locoregional therapy (LRT)…
2020 American Transplant Congress
Low Level CMV Detection and Effectiveness of Low Dose Valganciclovir Prophylaxis in Intermediate-Risk Liver Transplant Recipients
A. Nolan¹, B. Lovett², B. Lindner¹, J. G. Timpone³
¹Department of Pharmacy, Medstar Georgetown University Hospital, Washington, DC, ²Georgetown University School of Medicine, Washington, DC, ³Medstar Georgetown University Hospital, Washington, DC
*Purpose: The purpose of this study is to assess the efficacy of low dose (450 mg/day) valganciclovir in preventing CMV infection in intermediate-risk liver transplant…
2020 American Transplant Congress
T-cell Receptor Deep Sequencing to Distinguish Autoimmune Recurrence from Allograft Rejection in Liver Transplant Patients with Autoimmune Liver Disease
K. J. Yang¹, M. Martinez², B. Shonts¹, C. A. Parks¹, A. Z. Obradovic¹, T. M. Savage¹, E. Spyrou¹, S. Lau¹, M. I. Colquhoun¹, K. Rodgers¹, E. Verna³, S. M. Coley⁴, S. Yang¹, Y. Shen⁵, M. Sykes¹
¹Columbia Center for Translational Immunology, Department of Medicine, Columbia University, New York, NY, ²Department of Pediatrics, Columbia University, New York, NY, ³Department of Medicine, Columbia University, New York, NY, ⁴Department of Pathology, Columbia University, New York, NY, ⁵Center for Computational Biology & Bioinformatics, Department of Systems Biology, Columbia University, New York, NY
*Purpose: Patients who undergo liver transplantation for autoimmune liver disease (ALD) experience high rates of graft failure. The relative roles of recurrent ALD and rejection…
2020 American Transplant Congress
Liver Transplantation for Primary Liver Sarcoma in Children-The US Experience from the Scientific Registry for Transplant Recipients (1988-2018)
A. Amin, K. Soltys, S. Ranganathan, G. Bond, A. Khanna, A. Ganoza, Q. Sun, G. Mazariegos, R. Sindhi
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Primary liver sarcomas (PLS) are rare tumors and encompass subtypes with diverse histology and varying outcomes. These subtypes include embryonal sarcoma (ES), rhabdomyosarcoma (RMS),…
2020 American Transplant Congress
National Experience with Living Donor Liver Transplant for Hepatocellular Carcinoma
J. Silverstein¹, F. Yao¹, J. D. Grab², H. Braun², J. Roberts², J. Dodge², N. Mehta¹
¹Dept of Medicine, UCSF, San Francisco, CA, ²Dept of Surgery, UCSF, San Francisco, CA
*Purpose: LDLT is an attractive option to decrease both wait time and risk of waitlist dropout in HCC. This study aimed to evaluate temporal and…
2020 American Transplant Congress
Transmission of Synovial Sarcoma by a Single Multiorgan Donor to Three Solid Organ Transplant Recipients
J. Zhang, J. Lin, Y. Tian
Beijing Friendship Hospital, Capital Medical University, Beijing, China
*Purpose: To report 3 cases of donor-derived synovial sarcoma (SS) by a single multiorgan donor in China.*Methods: SS was diagnosed by the presence of SS18…