Articles tagged "Liver transplantation"

2020 American Transplant Congress
Preclinical Study for Liver Allograft Tolerance after Rapid Immunosuppression Withdrawal Using Cynomolgus Monkeys
H. Sakai¹, E. Berglund¹, S. Chaudhry¹, Y. Kato¹, J. Weiner¹, P. Alonso-Guallart¹, N. Llore¹, K. Bruestle¹, F. Fredriksson¹, J. Stern¹, D. Ekanayake-Alper¹, M. Martinez², G. Pierre¹, M. Danton¹, S. Kofman¹, D. Ordanes¹, J. Lefkowitch³, A. Iuga¹, T. Kato⁴, M. Sykes¹, A. Griesemer¹
¹Columbia Center for Translational Immunology, Department of Medicine, Columbia University, New York, NY, ²Department of Pediatrics, Columbia University, New York, NY, ³Departments of Pathology and Cell Biology, Columbia University, New York, NY, ⁴Department of Surgery, Columbia University, New York, NY
*Purpose: Operational tolerance of liver allografts occurs in highly selected patients but cannot be reliably induced. Herein, we investigated if tolerance to liver can be…
2020 American Transplant Congress
Renal Function Parameters Improve PELDs Prediction of 90-day Death or Deterioration
L. Thalji¹, N. Thalji², D. Haile¹, J. Heimbach², S. Ibrahim³, P. Kamath⁴, D. Kor¹
¹Anesthesiology, Mayo Clinic, Rochester, MN, ²Surgery, Mayo Clinic, Rochester, MN, ³Pediatric Gastroenterology, Mayo Clinic, Rochester, MN, ⁴Gastroenterology, Mayo Clinic, Rochester, MN
*Purpose: Reliance upon exception points to prioritize children for liver transplantation (LT) stems from concerns that the Pediatric End-Stage Liver Disease (PELD) score underestimates mortality.…
2020 American Transplant Congress
Evaluating the Efficacy of Robotic-Assisted Incisional Hernia Repair for Post-Liver Transplant Recipients
G. Rofaiel, G. Pan, M. Goodale, E. Martinez
University of Utah, Salt Lake City, UT
*Purpose: Hernia formation is a well-known complication following open abdominal surgery that contributes to post-operative morbidity and decreases in patient quality of life. Herein we…
2020 American Transplant Congress
Waiting List Mortality of Liver Tumors
V. G. Menon, Y. Chen, D. C. Chang, H. Yeh
Division of Transplantation, Massachusetts General Hospital, Boston, MA
*Purpose: Liver transplantation has been approved for hepatocellular carcinoma (HCC), hilar cholangiocarcinoma (CCA) and metastatic neuroendocrine tumors (NET), with the aim to produce similar outcomes…
2020 American Transplant Congress
Myosteatosis and its Impact on Graft- and Patient Survival in Adult Recipients of Deceased Donor Liver Transplantation
Z. Czigany, W. Kramp, G. van der Kroft, P. Strnad, M. Zimmermann, W. Liu, G. Wiltberger, U. Neumann, G. Lurje
University Hospital RWTH Aachen, Aachen, Germany
*Purpose: Recently our group demonstrated the role of myosteatosis in inferior perioperative outcomes (Czigany et al. Am J Transplant 2019) in recipients of orthotopic liver…
2020 American Transplant Congress
Persistent Fibrinolysis Shutdown in Liver Transplant Recipients is Associated with Early Allograph Dysfunction
H. B. Moore¹, T. Nydam¹, J. Pomposelli¹, C. Walker¹, A. Schulick¹, R. Choudhury¹, H. Yaffe¹, M. Adams², M. Cohen³, E. Pomfret¹
¹University of Colorado, Aurora, CO, ²Childrens Hospital, Aurora, CO, ³Denver Health Medical Center, Denver, CO
*Purpose: Early allograph dysfunction (EAD) in liver transplantation has been attributed to microvascular thrombosis. Treating grafts at risk of EAD with tissue plasminogen activator (tPA)…
2020 American Transplant Congress
Liver Transplantation as a Salvage and Uncommon Procedure for a Patient with Colorectal Liver Metastsis with Promising Results, Case Presentation and Literature Review
M. Tabbal, M. Al Qahtani
Transplant Surgery, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia
*Purpose: Colorectal cancer (CRC) is the third most common cancer worldwide. About 50% of patients with CRC will develop metastases during the course of the…
2020 American Transplant Congress
Impact of Patent Foramen Ovale on Post Liver Transplant Neurological Outcomes
S. Naffouj, F. Nimri, M. Mohammed, E. Abu-Asala, L. Al-khatib, M. Abu-Ghanimeh, D. Venkat
Henry Ford Hospital, Detroit, MI
*Purpose: The presence of patent foramen ovale (PFO) can result in intra-cardiac shunting of atheromatous debris during liver transplantation (LT) given the acute hemodynamic changes…
2020 American Transplant Congress
Factors Associated with High Mortality in Acute on Chronic Liver Failure Patients Admitted to the Intensive Care Unit, Single Center Experience
O. Mendez Guerrero, D. A. Calle Rodas, E. Cervantes Alvarez, E. Alatorre Arenas, J. Perez Escobar, A. Estanes Hernandez, N. Navarro Alvarez, A. Torre
Hepatology and Liver Transplantation Unit, Gastroenterology department, National Institute of Medical Science and Nutrition Salvador Zubiran, Mexico City, Mexico
*Purpose: ACLF is a newly defined syndrome in the background of a chronic liver disease characterized by acute decompensation, organ failure and high mortality at…
2020 American Transplant Congress
What is the Significance of Denovo Donor Specific Antibodies in Recipients of Simultaneous Liver-Kidney Transplants?
S. Parajuli, F. Aziz, J. Blazel, B. Muth, N. Garg, M. Mohamed, J. Rice, J. Mezrich, L. Hidalgo, D. Mandelbrot, G. Im, B. Lee
University of Wisconsin, Madison, WI
*Purpose: There is limited information about the utility of donor-specific HLA antibody (DSA) testing and the role of protocol kidney biopsy for de-novo donor-specific antibodies…