Articles tagged "Liver transplantation"

2020 American Transplant Congress
Because That is Not How The Hierarchy Works: Primary Care Provider Perspectives on Liver Transplant Referral and Access to Transplant
V. Madabhushi¹, A. Murphy², C. Reams³, R. Gedaly³, M. Shah³, N. Pope⁴, M. Gupta⁵
¹General Surgery, University of Kentucky, Lexington, KY, ²University of Kentucky, College of Medicine, Lexington, KY, ³Surgery, DIvision of Transplant Surgery, University of Kentucky, Lexington, KY, ⁴University of Kentucky, College of Social Work, Lexington, KY, ⁵Surgery, Division of Transplant Surgery, University of Kentucky, Lexington, KY
*Purpose: In rural America, the road to obtaining a liver transplant (LTX) often starts at the primary care provider’s (PCP) office. Patients in rural communities…
2020 American Transplant Congress
Single Cell RNA Sequencing Analysis of 3 Human Living-Donor Liver Transplant Allograft Biopsies after Infusion of Donor-Derived Regulatory Dendritic Cells
L. M. Tran¹, T. Tabib², A. F. Zahorchak¹, R. Lafyatis², M. A. Styn¹, A. Humar¹, F. G. Lakkis¹, D. M. Metes¹, A. W. Thomson¹
¹Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, ²Department of Medicine and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA
*Purpose: Single-cell RNA sequencing is an emerging, powerful genomic technology that can describe heterogenous cellular populations of whole solid organs with high resolution. We report…
2020 American Transplant Congress
Temporal Trends in the Incidence and Impact of Biliary Complications Following Liver Transplantation
K. R. Jackson¹, K. Lentine², M. Schnitzler², Z. Zhang², H. Xiao², J. Motter¹, D. Axelrod³, D. Segev¹
¹Johns Hopkins University, Baltimore, MD, ²Saint Louis University, Saint Louis, MO, ³University of Iowa, Iowa City, IA
*Purpose: Biliary complications (BC) are a major threat to successful liver transplantation (LT), as they are associated with a subsequent higher risk of mortality and…
2020 American Transplant Congress
Pediatric Liver Post-Transplant Length of Stay Index
T. Zhang¹, S. Barrett¹, R. Cotton², T. Galvan², J. Vierling², C. O'Mahony², J. Goss², A. Rana²
¹Medical Student, Baylor College of Medicine, Houston, TX, ²Baylor College of Medicine, Houston, TX
*Purpose: PELD scores are used to reduce waitlist mortality, but they do not accurately predict likelihood of prolonged length of stay or higher costs associated…
2020 American Transplant Congress
Inactive Status Change is an Independent Predictor of Waitlist Mortality and Disproportionately Impacts Patients in Donor Service Areas with a Higher Median MELD at Transplant
R. Batra¹, S. Noreen², D. Stewart³, D. Haakinson¹, G. Gan³, Y. Deng³, S. Kulkarni¹
¹Surgery, Yale University School of Medicine, New Haven, CT, ²UNOS, Richmond, VA, ³Yale University, New Haven, CT
*Purpose: Liver waitlist mortality is calculated by including both active and inactive patients. As inactive patients are unable to receive organ offers, models that adjust…
2020 American Transplant Congress
Liver Live Donor Champion: Advocacy Training to Facilitate Identification of Live Liver Donors
A. D. Love¹, L. R. Herbst¹, D. R. Helfer¹, L. Kurman², M. G. Bowring¹, S. R. Weeks¹, E. King¹, D. L. Segev¹, J. Garonzik Wang¹
¹Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, ²Surgery, The Johns Hopkins Hospital, Baltimore, MD
*Purpose: Although live donor liver transplantation (LDLT) may help address organ shortage, patients lack knowledge about living donation and are reluctant to speak to potential…
2020 American Transplant Congress
New Concept of Liver Transplatation in Pediatric Patient – Up Side Down Metod
P. Dubska, L. Janousek, J. Chlupac, M. Kocik, J. Fronek
Transplantation Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Liver transplantation (LTx) in pediatrics has become an accepted modality for treatment in end-stage liver disease and irreversible acute liver failure. Left lateral segment…
2020 American Transplant Congress
Association of Perfusion Characteristics and Post-Transplant Liver Function in Ischemia-Free Liver Transplantation
Z. Zhang, Y. Tang, Q. Zhao, Z. Guo, X. He
The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: It has been showed that normothermic machine perfusion (NMP), a novel preservation method, is able to assess and resuscitate liver grafts with risk factors.…
2020 American Transplant Congress
Timing of Bariatric Surgery for Obese Liver Transplant Candidates
R. A. Choudhury¹, D. Yoeli², G. Hoeltzel³, H. B. Moore², H. Yaffe², K. R. Dumon⁴, N. N. Williams⁴, P. L. Abt⁵, K. D. Conzen², J. J. Pomposelli², E. A. Pomfret², T. L. Nydam²
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Denver, CO, ²Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ³Thomas Jefferson University Hospital, Philadelphia, PA, ⁴Department of Surgery, University of Pennsylvania Hospital, Philadelphia, PA, ⁵Department of Surgery- Division of Transplantation Surgery, University of Pennsylvania Hospital, Philadelphia, PA
*Purpose: The timing of bariatric surgery for obese liver transplant candidates remains controversial. Surgery prior to transplant may improves one’s chance of receiving a transplant,…
2020 American Transplant Congress
Salvaging Discarded Livers with Normothermic Machine Perfusion: Is it Worth the Cost?
R. J. de Vries, S. Raigani, C. Carroll, Y. Chen, D. C. Chang, J. F. Markmann, K. Uygun, H. Yeh
Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA
*Purpose: Normothermic machine perfusion (NMP) enables transplantation of discarded grafts with excellent outcomes in clinical trials. The cost of deploying NMP is often cited as…