Articles tagged "Liver transplantation"

2021 American Transplant Congress
Dual Liver and Kidney Donors, What Makes Them Decide to Do It?
H. Al Harakeh, B. Emmanuel, C. Hughes, A. Tevar, J. Steel, A. F. DiMartini, S. Ganesh, A. Humar
Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: There is incongruity between the transplant waiting list and the number of deceased donors available, therefore there is an enduring challenge to increase the…
2021 American Transplant Congress
The Evolution of the National Liver Review Board
S. Noreen¹, J. Trotter², J. Pomposelli³, M. Cafarella¹, J. Heimbach⁴
¹UNOS, Richmond, VA, ²BSWHealth, Dallas, TX, ³UCHealth, Aurora, CO, ⁴Mayo Clinic, Rochester, MN
*Purpose: The National Liver Review Board (NLRB) was implemented 5/14/2019, establishing a national structure for liver exceptions comprised of three specialty review boards and a…
2021 American Transplant Congress
Influence of Frailty on Psychometric Factors and Health-related Quality of Life in Patients on the Waitlist for Liver Transplantation
C. G. Klein, J. Latuske, E. Malamutmann, A. Paul, A. Oezcelik
University Medicine Essen, Essen, Germany
*Purpose: The aim of this prospective study was to evaluate the influence of frailty on depression, anxiety and health-related quality of life for patients on…
2021 American Transplant Congress
Ikaros-SIRT1 Signaling Axis Regulates Macrophage Polarization and Ischemia Reperfusion Injury in Mouse and Human Liver Transplantation
K. Kadono¹, H. Hirao¹, H. Kojima¹, K. J. Dery¹, X. Li², J. W. Kupiec-Weglinski¹
¹The Dumont-UCLA Transplant Center, Los Angeles, CA, ²NIEHS, Durham, NC
*Purpose: Although Ikaros is a well-established transcriptional regulator of lymphopoiesis and differentiation of leukocyte lineage, its role in myeloid cells and ischemia reperfusion injury remain…
2021 American Transplant Congress
Cross-Circulation for Extracorporeal Liver Support in a Swine Model
W. K. Wu¹, A. Tumen¹, J. W. Stokes², R. Ukita², A. E. Hozain³, C. R. Flynn², M. J. Lee³, J. R. Talackine², N. L. Cardwell², J. A. Reimer³, M. Pinezich³, C. Benson², G. Vunjak-Novakovic³, S. P. Alexopoulos², M. Bacchetta²
¹co-first authors, Vanderbilt University Medical Center, Nashville, TN, ²Vanderbilt University Medical Center, Nashville, TN, ³Columbia University Medical Center, New York, NY
*Purpose: Although machine perfusion has gained momentum as an organ preservation strategy in liver transplantation, significant organ shortages and waitlist mortality persist, highlighting unmet needs…
2021 American Transplant Congress
MiRNA as Regulator of Cell Death and Inflammatory Response in Hepatic Iri
E. Bardhi¹, T. Rousselle¹, J. McDaniels¹, S. Bontha¹, J. Eason², D. Maluf¹, V. Mas³
¹Surgery, University of Maryland, Baltimore, MD, ²Surgery, James D Eason Transplant Institute, Memphis, TN, ³Surgery, University of Maryland - Division of Surgical Science, Baltimore, MD
*Purpose: Hepatic IRI represents a barrier to the use of available organs. Early graft dysfunction of donor livers is directly related to the severity of…
2021 American Transplant Congress
Seroprevalence of SARS-CoV-2 Antibodies in Transplant Recipients in a Croatian Transplant Center
A. Mrzljak¹, Z. Jurekovic¹, J. Pavicic Saric², L. Antolasic³, L. Milasincic³, I. Tabain³, T. Vilibic Cavlek³
¹Department of Internal Medicine, Merkur University Hospital, Zagreb, Croatia, ²Department of Anesthesiology, Merkur University Hospital, Zagreb, Croatia, ³Department of Microbiology, Croatian Institute of Public Health, Zagreb, Croatia
*Purpose: In Croatia, the first case of coronavirus disease (COVID-19) has been reported on 25 February 2020; however, the COVID-19 seroprevalence in the liver (LTR)…
2021 American Transplant Congress
Transplant-free Survival in Alcohol-related Liver Disease (ALD) Patients Presenting with First Evidence of Ascites
K. Fahoum¹, N. T. Shen², E. Basu¹, J. Lee³, A. Kaplan², A. Salajegheh⁴, R. Rosenblatt², A. Jesudian², C. Lucero², B. Fortune², M. M. Safford⁵, R. S. Brown²
¹Medical College, Weill Cornell Medicine, New York, NY, ²Gastroenterology and Hepatology, Weill Cornell Medicine, New York, NY, ³Population Health Sciences, Weill Cornell Medicine, New York, NY, ⁴Psychiatry, Weill Cornell Medicine, New York, NY, ⁵General Internal Medicine, Weill Cornell Medicine, New York, NY
*Purpose: The development of ascites is a poor prognostic sign for patients with cirrhosis. The factors associated with transplant-free survival at initial presentation with ascites…
2021 American Transplant Congress
Effects of TIPS on Transplant Outcomes for HCC
C. L. Hanlon¹, D. Toy¹, Y. Liu¹, S. Zhou¹, K. Zhou², J. Kahn², L. Yuan²
¹Internal Medicine, University of Southern California, Los Angeles, CA, ²Internal Medicine - Department of Gastroenterology and Hepatology, University of Southern California, Los Angeles, CA
*Purpose: The purpose of this study is to examine effects of TIPS placement on response to locoregional therapy (LRT) and clinical outcomes after liver transplantation…
2021 American Transplant Congress
Outcomes of DCD Allografts in Liver Transplant Recipients with HCC
N. Gupta¹, J. Daum¹, B. Aqel², L. Mi³, J. Harbell⁴
¹School of Medicine, Mayo Clinic Arizona, Phoenix, AZ, ²Hepatology, Mayo Clinic Arizona, Phoenix, AZ, ³Biostatistics, Mayo Clinic Arizona, Phoenix, AZ, ⁴Transplant Surgery, Mayo Clinic Arizona, Phoenix, AZ
*Purpose: Early studies demonstrated inferior survival for liver transplant (LT) recipients with hepatocellular carcinoma (HCC) who received allografts from donation after cardiac death (DCD) donors…