Articles tagged "Liver transplantation"

2021 American Transplant Congress
Should We Worry About Covid-19 Infection in Pediatric SOT?
U. Ekong¹, S. Paul¹, S. Royal², J. Chahine³, N. Yazigi¹, S. Kaufman¹, K. Khan¹, C. Matsumoto¹, A. Kroemer¹, T. Fishbein¹
¹Surgery, Medstar Georgetown Transplant Institute, Washington, DC, ²Pediatrics, Medstar Georgetown University Hospital, Washington, DC, ³Pathology and Laboratory Medicine, Medstar Georgetown University Hospital, Washington, DC
*Purpose: We describe the clinical presentation & immune response to COVID-19 infection in pediatric SOT.*Methods: Medical records of COVID-19 PCR+ or seropositive patients were reviewed…
2021 American Transplant Congress
Hepatitis E Diagnosis and Management After Liver, Kidney, or Heart Transplant: A Single Center Experience
M. Carter¹, M. Fitzmaurice², S. Yeddula², A. Singh², S. Nagai², S. Jafri²
¹Wayne State University School of Medicine, Detroit, MI, ²Henry Ford Health System, Detroit, MI
*Purpose: Transplant-related Hepatitis E virus (HEV) infection is a rarely recognized entity with significant clinical importance given potential for chronic hepatitis post-transplant. We evaluated HEV…
2021 American Transplant Congress
Dynamics of IgG Subclass as a Mechanism of Desensitization Using Rituximab for Presensitized Patients Undergoing Living Related Liver Transplantation
H. Egawa¹, K. Ide², T. Ishizuka³, H. Ohdan⁴, Y. Kotera¹, T. Kato¹, A. Ohmori¹, Y. Hirata¹, G. Shibuya¹, S. Yamashita¹, S. Ariizumi¹
¹Tokyo Women's Medical University, Tokyo, Japan, ²Surgery, Hiroshima University, Hiroshima, Japan, ³Clinical Laboratory, Tokyo Women's Medical University, Tokyo, Japan, ⁴Hiroshima University, Hiroshima, Japan
*Purpose: Although impact of preformed HLA-related donor specific antibody (DSA) and necessity of desensitization in liver transplantation (LT) has been recognized, mechanisms of desensitization in…
2021 American Transplant Congress
Intrahepatic Spatial Location of HCC Recurrence Following Loco-regional Therapy for Solitary Tumors Predicts a Higher Oncologic Risk & Increased Recurrence Post-transplant
A. Mathur, E. Baughan, S. Haider, A. Griesemer, T. Kato, J. Emond
Columbia University, New York, NY
*Purpose: Loco-Regional therapy (LRT) for hepatocellular carcinoma (HCC) patients is an established bridge to Orthotopic Liver Transplantation (OLT). However, no large cohort data exist correlating…
2021 American Transplant Congress
Long-term Outcomes of Donation After Cardiac Death and Living Donor Liver Transplant for Primary Sclerosing Cholangitis: An Analysis of UNOS Registry from 2002-2020
T. Kitajima, S. Nagai, T. Ivanics, T. Shamaa, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, D. Moonka
Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI
*Purpose: Use of donation after circulatory death (DCD) grafts is a reported risk factor for worse outcomes after liver transplant (LT) for primary sclerosing cholangitis…
2021 American Transplant Congress
Thrombotic and Hemorrhagic Complications Associated with Postoperative Anticoagulation After Pediatric Liver Transplantation
C. Lemoine, K. Brandt, R. Superina
Division of Transplant and Advanced Hepatobiliary Surgery, Ann & Robert H. Lurie Children's Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL
*Purpose: In order to determine the efficacy of post-liver transplant (LT) anticoagulation protocols in reducing the occurrence of arterial thrombosis (HAT) and other vascular complications…
2021 American Transplant Congress
A Novel Liver Assist Device as a Bridge to Liver Transplantation in Acute on Chronic Liver Failure Patients with Multi-Organ Failure
S. Ahmad¹, I. W. Liou¹, J. Reyes², R. Bakthavatsalam³, N. C. Smith⁴, R. L. Carithers¹, C. Martin¹, D. Gao⁵
¹Medicine, University of Washington, Seattle, WA, ²Surgery, University of Washington, SEATTLE, WA, ³Surgery, University of Washington, Seattle, WA, ⁴Nursing, University of Washington, Seattle, WA, ⁵Engineering, University of Washington, Seattle, WA
*Purpose: Acute on chronic liver failure (AOCLF) occurs in nearly 25% of patients with acutely decompensated cirrhosis, with many developing multi-organ failure requiring ventilatory, vasopressor…
2021 American Transplant Congress
Donor-derived Cell-free DNA Distinguishes Acute Rejection from Other Causes of Graft Injury in Liver Transplant Recipients
J. Levitsky¹, M. Miller², R. Sinha², E. Bixler², A. Al-Turck², J. Weems², M. Altrich², S. Kleiboeker², M. Abecassis³
¹Gastroenterology & Hepatology; Comprehensive Transplant Center, Northwestern University, Chicago, IL, ²Viracor Eurofins, Lees Summit, MO, ³University of Arizona College of Medicine Tucson, Tucson, AZ
*Purpose: The donor derived cell-free DNA (ddcfDNA) has emerged as strong biomarker for allograft injury, where the fraction of ddcfDNA is reported to increase in…
2021 American Transplant Congress
De Novo Hepatitis B Infection Following Liver Transplant with Hepatitis B Core Antibody Positive Graft
L. J. Myhre¹, K. D. Watt², B. A. Aqel³
¹Pharmacy, Mayo Clinic, Rochester, MN, ²Gastroenterology/Hepatology, Mayo Clinic, Rochester, MN, ³Gastroenterology/Hepatology, Mayo Clinic, Phoenix, AZ
*Purpose: The risk of de novo HBV infection in liver transplant recipients of Hepatitis B core antibody (HBcAb) positive donor organs is tempered by availability…
2021 American Transplant Congress
Severe Hypoxemia After Liver Transplantation in the Hepatopulmonary Syndrome
J. Doi, M. Fujiki, G. DAmico, K. Sasaki, T. Diago, F. Aucejo, C. Kwon, B. Eghtesad, K. Hashimoto, C. Miller, Q. Cristiano
Cleveland Clinic, Cleveland, OH
*Purpose: Hepato-pulmonary syndrome (HPS) is a complication of liver disease with liver transplantation as the only curative treatment. However these patients can develop severe hypoxemia…