Articles tagged "Liver transplantation"

2021 American Transplant Congress
DAP12 Promotes Liver DC Tolerogenicity by Negative Regulation of the CGAS-STING-IFN I Pathway
Y. Zheng¹, J. Long², N. Ryosuke¹, L. Peng³, F. Peng³, A. Thomson¹
¹Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, ²Department of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China, ³Department of Kidney Transplantation, The Second Xiangya Hospital of Central South University, Changsha, China
*Purpose: Constitutive expression of comparatively high levels of DNAX-activating protein of 12KDa (DAP12) by liver myeloid dendritic cells (mDCs) has been implicated in their immune…
2021 American Transplant Congress
Death and Loss to Follow-up in Pediatric Liver Transplant Recipients Transferred to Adult Care: Who is at Risk?
J. P. Stevens¹, S. Gillespie¹, M. Katz¹, L. Hall², V. Kolachala¹, R. Ford³, N. A. Gupta¹
¹Pediatrics, Emory University School of Medicine, Atlanta, GA, ²Transplant Services, Children's Healthcare of Atlanta, Atlanta, GA, ³Internal Medicine, Emory University School of Medicine, Atlanta, GA
*Purpose: With improvements in surgical technique and immunosuppressive regimens, many pediatric liver transplant recipients are surviving to adulthood. Successful transition to an adult provider is…
2021 American Transplant Congress
Development of Novel Multivariable Logistic Regression Model for Predicting Acute Kidney Injury After Liver Transplantation
H. Chen, Y. Nie, Q. Zhao, X. He
Organ Transplant Center,, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Acute kidney injury (AKI) is a common early complication after liver transplantation, but there are no related predictive tools or models at present. The…
2021 American Transplant Congress
Serum Phosphatidylethanol is Superior to Urine Ethyl Glucuronide for Detection of Alcohol Use in Pre-transplant Patients
N. Lim¹, T. Leventhal¹, M. Thomson¹, M. Hassan¹, J. Thompson¹, S. Chinnakotla², V. Kirchner², T. Pruett², R. Kandaswamy², V. Humphreville², A. Adams², J. Lake¹
¹Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, ²Division of Transplantation, University of Minnesota, Minneapolis, MN
*Purpose: More patients are presenting for liver transplant (LT) evaluation for alcohol-related liver disease (ALD). Detection of ETOH use has significant implications for patients undergoing…
2021 American Transplant Congress
Adult Deceased Donor Liver Transplantation with Split Liver Grafts vs Whole Liver Grafts. A Single-Center Experience
P. Vargas¹, C. Argo², H. Zachary², M. Stotts², N. Intagliata², P. Northup², S. Pelletier¹, J. Oberholzer¹, N. Goldaracena¹
¹Transplant Surgery, University of Virginia Health System, Charlottesville, VA, ²Gastroenterology and Hepatology, University of Virginia Health System, Charlottesville, VA
*Purpose: The present study aims to report outcomes of adults following SLT in a single-center and compare this selected group with adults recipients following whole…
2021 American Transplant Congress
Assessing Liver Transplant Outcomes Utilizing Post-Cross Clamp Offers
K. Pont¹, E. Macdonough¹, D. Das², K. Valenti¹, P. Morgan¹, B. Aqel¹, A. Mathur¹, A. Moss¹, K. S. Reddy¹, C. Jadlowiec¹
¹Mayo Clinic, Phoenix, AZ, ²Mayo Clinic Alix School of Medicine, Scottsdale, AZ
*Purpose: With the ongoing organ shortage, there has been increased interest in utilizing post-cross clamp (XC) liver allografts as a means of expanding the donor…
2021 American Transplant Congress
Intravenous Immunoglobulin Protects Liver Allograft from Ischemia Reperfusion Injury in Human Liver Transplantation
S. Yokota, J. C. Alonso-Escalante, R. P. Tindall, K. R. Tabar, L. Machado, T. Uemura, N. L. Thai
Department of Surgery, Allegheny General Hospital, Pittsburgh, PA
*Purpose: Ischemia/reperfusion (I/R) injury following prolonged cold storage has a significant impact on early and late human liver transplantation (LTx) outcomes. Prevention of I/R injury…
2021 American Transplant Congress
Adjuvant Immunotherapy for Liver Transplant Recipients with Hepatocellular Carcinoma Using Donor Liver-derived Natural Killer Cells
M. Ohira¹, R. Hotta¹, Y. Imaoka¹, K. Sato¹, N. Tanimine¹, Y. Tanaka¹, S. Nishida², A. Tzakis², H. Ohdan¹
¹Hiroshima University, Hiroshima, Japan, ²University of Miami, Miami, FL
*Purpose: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and is an indication for liver transplantation (LT). Immunosuppressive regimens currently used after…
2021 American Transplant Congress
State-level Trend in the Prevalence of Non-alcoholic Steatohepatitis for Liver Transplant Candidates in the United States, 2001-2017
S. Chang¹, M. Wang¹, M. Pozo², D. Ladner², D. Borja-Cacho²
¹Washington University School of Medicine, Saint Louis, MO, ²Northwestern University, Chicago, IL
*Purpose: As variation in the prevalence of obesity across states continues to grow, the prevalence of nonalcoholic steatohepatitis (NASH) is also rising. However, little is…
2021 American Transplant Congress
Recipient Selector for Donation After Cardiac Death Allografts
G. Handing¹, S. Ganni², S. Barrett¹, N. Galvan², C. O’Mahony², J. Goss², R. Cotton², A. Rana²
¹School of Medicine, Baylor College of Medicine, Houston, TX, ²Michael E DeBakey Department of Surgery, Division of Abdominal Transplant, Houston, TX
*Purpose: Donation after cardiac death (DCD) allografts might represent one of the largest untapped sources of liver allografts. Our aim was to identify independent donor…