Articles tagged "Liver transplantation"

2021 American Transplant Congress
Analysis of Single Cell RNA Sequencing Data to Define Biomarkers of Human Liver Immune Tolerance
B. Rocque¹, A. Barbetta¹, P. Singh¹, C. Goldbeck¹, D. G. Helou², E. Loh³, N. Ung⁴, J. S. Lee⁴, O. Akbari², J. Emamaullee¹
¹Surgery, University of Southern California Keck School of Medicine, Los Angeles, CA, ²Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, ³Norris Medical Library, University of Southern California Keck School of Medicine, Los Angeles, CA, ⁴Ellison Institute, University of Southern California, Los Angeles, CA
*Purpose: The liver is unique in its ability to maintain immune homeostasis and promote operational tolerance following solid organ transplantation. Single-cell RNA sequencing (scRNA seq)…
2021 American Transplant Congress
Serum Phosphatidylethanol is Superior to Urine Ethyl Glucuronide for Diagnosis of Alcohol Relapse in Liver Transplant Recipients
N. Lim¹, T. Leventhal¹, M. Thomson¹, M. Hassan¹, J. Thompson¹, S. Chinnakotla², V. Kirchner², T. Pruett², R. Kandaswamy², V. Humphreville², A. Adams², J. Lake¹
¹Divison of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, ²Divison of Transplantation, University of Minnesota, Minneapolis, MN
*Purpose: Liver transplantation (LT) for alcohol-related liver disease (ALD) is increasing. The primary issue in these patients is often recidivism, therefore screening for ETOH use…
2021 American Transplant Congress
Liver Transplantation in Septuagenarians
L. Egbert¹, D. Das¹, S. Ohara², J. Wagler³, G. Mahdi⁴, B. Aqel⁵, A. Moss⁵, K. S. Reddy⁵, C. Jadlowiec⁵
¹Mayo Clinic Alix School of Medicine, Scottsdale, AZ, ²Valleywise Health General Surgery Residency Program, Phoenix, AZ, ³HonorHealth John C. Lincoln, Phoenix, AZ, ⁴Mayo Clinic Alix School of Medicine, Phoenix, AZ, ⁵Mayo Clinic, Phoenix, AZ
*Purpose: The average age of liver transplant (LT) recipients has continued to increase. In spite of this, with the ongoing organ shortage, liver transplantation in…
2021 American Transplant Congress
The Surgical Experience and Treatment Options for Hepatic Cystic Disease
M. Crowley¹, K. Robichaux², A. Kumar¹, J. Buggs³, J. Sokolich⁴
¹Morsani College of Medicine, University of South Florida, Tampa, FL, ²Honors College, University of South Florida, Tampa, FL, ³Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁴Hepatobiliary Surgery, Valley Presbyterian Hospital, San Fernando Valley, CA
*Purpose: Benign hepatic cysts may require surgical removal when symptomatic particularly in the setting of genetic disorders such as autosomal dominant polycystic kidney disease (ADPKD)…
2021 American Transplant Congress
The Survival Benefits of Using Marginal Allografts in Liver Transplantation
T. H. Malik¹, E. L. Godfrey¹, A. Rana²
¹Baylor College of Medicine, Houston, TX, ²Department of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: Our study assessed whether using marginal allografts at initial time of listing provided similar or greater survival benefit versus waiting on the transplant waitlist…
2021 American Transplant Congress
Hepatoportoenterostomy versus Primary Liver Transplantation for Biliary Atresia: A Review of the National Experience
D. Yoeli¹, R. A. Choudhury¹, S. S. Sundaram², C. L. Mack², J. P. Roach³, F. M. Karrer⁴, M. E. Wachs¹, M. A. Adams¹
¹Transplant Surgery, University of Colorado and Children's Hospital Colorado, Aurora, CO, ²Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado and Children's Hospital Colorado, Aurora, CO, ³Pediatric Surgery, University of Colorado, Aurora, CO, ⁴Pediatric Surgery, University of Colorado and Children's Hospital Colorado, Aurora, CO
*Purpose: Kasai hepatoportoenterostomy (HPE) followed by liver transplantation (LT) if needed is the standard of care for children with biliary atresia (BA). Some, however, have…
2021 American Transplant Congress
Home-based Liver Frailty Intervention (lift) in Liver Transplant Candidates: A Pilot Study
A. J. Thuluvath¹, K. Belfanti¹, S. Morrissey¹, O. Siddiqui¹, J. Peipert¹, A. Daud¹, J. Levitsky¹, T. Bogg², A. Flores¹, D. P. Ladner¹
¹Northwestern University Transplant Research Collaborative, Chicago, IL, ²Department of Psychology, Wayne State University, Detroit, MI
*Purpose: Frailty is highly prevalent in patients awaiting LT and is associated with increased waitlist and post-transplant mortality, hospitalizations and LOS. While reduction of frailty…
2021 American Transplant Congress
Impact of a Pharmacist-driven Immunization Clinic on Vaccination Rates in Pre-liver Transplant Patients
A. Poparad-Stezar¹, B. Summers¹, M. Fitzmaurice¹, K. Hakamiun², N. Sulejmani³, A. Jantz¹
¹Henry Ford Hospital, Detroit, MI, ²Select Medical, Wyandotte, MI, ³CareDx, Inc., Sterling Heights, MI
*Purpose: Infectious diseases are a leading cause of morbidity and mortality among patients with end-stage liver disease (ESLD). Vaccination data of ESLD patients pre- and…
2021 American Transplant Congress
A Meta-Analysis of Endoscopic Stents in the Treatment of Anastomotic Biliary Strictures After Liver Transplantation
F. Zhou¹, M. Mieth¹, C. Rupp², A. Mehrabi¹, A. Nickkholgh¹
¹Department of General, Abdominal and Transplant Surgery, University of Heidelberg, Heidelberg, Germany, ²Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany
*Purpose: Biliary strictures (BS) are common after orthotopic liver transplantation (OLT). The treatment of choice is endoscopic retrograde cholangiopancreatography (ERCP). Multiple plastic stents (MPS) have…
2021 American Transplant Congress
Prevalence of Hepatitis E Virus Infection in Solid Organ Transplant Recipients: A Systematic Review and Meta-analysis
P. Hansrivijit¹, A. Trongtorsak², B. Boonpheng³, C. Thongprayoon⁴, W. Cheungpasitporn⁴
¹Department of Internal Medicine, UPMC Pinnacle, Harrisburg, PA, ²Department of Internal Medicine, Amita Health Saint Francis Hospital, Evanston, IL, ³Division of Nephrology, David Geffen School of Medicine, University of California, Los Angeles, CA, ⁴Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN
*Purpose: Hepatitis E virus (HEV) infection is an underdiagnosed disease due to the use of serological assays with low sensitivity. Although most patients with HEV…