Articles tagged "Liver transplantation"

2015 American Transplant Congress
National Transplantation Pregnancy Registry: Cholestasis of Pregnancy in Liver Transplant Recipients
M. Moritz,^1,2 L. Coscia,² S. Constantinescu,³ D. Armenti.²
¹Lehigh Valley Health Network, Allentown; ²National Transplantation Pregnancy Registry, Gift of Life Institute, Philadelphia; ³Temple University School of Medicine, Philadelphia.
Cholestasis of pregnancy (COP) occurs in approximately 1% of pregnancies and is associated with increased risk of premature delivery. The purpose of this study was…
2015 American Transplant Congress
Identifying the “Operational Tolerant” Pediatric Liver Transplant Recipient by Cytometry by Time-of-Flight
A. Lau,^1,2 M. Vitalone,¹ K. Haas,³ T. Shawler,¹ C. Esquivel,¹ O. Martinez,¹ R. Castillo,³ S. Krams.¹
¹Surgery, Division of Abdominal Transplantation, Stanford University, Stanford, CA; ²Pediatrics, Div. Gastroenterology, Hepatology, and Nutrition, University of California, San Francisco, San Francisco, CA; ³Pediatrics, Div. Gastroenterology, Hepatology, and Nutrition, Stanford University, Stanford, CA.
Liver allografts are known to be well tolerated and indeed, some recipients of liver allografts retain stable graft function in the absence of immunosuppression. The…
2015 American Transplant Congress
Outcomes Between ABO-Incompatible Living Donor Liver Transplantation (LDLT) and ABO-Compatible LDLT: A Matched Study
J. Kim, S. Lee, W. Cho, J.-Y. Choi, G.-S. Choi, J. Park, C. Kwon, S. Kim, J.-W. Joh, S.-K. Lee.
Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Backgrounds: Reports from several experienced centers suggested that outcomes of an ABO-incompatible (ABOi) living donor liver transplantation (LDLT) after rituximab and reduction of ABO antibodies…
2015 American Transplant Congress
Pediatric Living Donor Liver Transplantation at KFSH&RC – Implementation of the Laparoscopic Retrieval in a High Volume Center
M. Boehnert, M. Shagrani, T. Al Goufi, D. Broering.
Organ Transplant Centre, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
Since the first successful pediatric liver transplantation was performed in 1967 the survival rate increased from 30 % to currently above 90 %. This is…
2015 American Transplant Congress
Renal Function Following Basiliximab Induction in Liver Transplant Recipients
J. Hagopian, T. Horwedel, L. Bowman, K. Collins, M. Doyle.
Washington University School of Medicine, St. Louis.
Purpose: Reports of the use of antibody induction to delay the start of calcineurin inhibitor therapy postoperatively in patients with renal insufficiency at the time…
2015 American Transplant Congress
Combined Bone Marrow Plus Liver Transplantation in Cynomolgus Monkeys
J. Weiner, Y. Kato, R. Duran-Struuck, M. Martinez, S. Baker, P. Alonso, J. Zitsman, A. Wu, P. Houck, T. Pinyavat, J. Lefkowitch, S. Chaudhry, T. Kato, M. Sykes, A. Griesemer.
Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY.
IntroductionCombined kidney/bone marrow transplantation (CKBMT) induces tolerance in both primates and humans. Since liver is thought to be more tolerogenic than kidney, we hypothesized that…
2015 American Transplant Congress
HLA-C, KIR Genotypes and KIR Genotype/HLA –C Ligand Combination in Prediction of Early Acute Rejection After Liver Transplantation
K. Park,¹ J. Ryu,¹ H. Park,³ Y. Kim,² E.-J. Oh.²
¹Biomedical Science, Graduate School, The Catholic University of Korea, Seoul, Republic of Korea; ²Laboratory Medicine, Seoul St. Mary's Hospital, the Catholic University of Korea, Seoul, Republic of Korea; ³Medical Science, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Introduction; Interaction of killer immunoglobulin-like receptors (KIRs) and human leukocyte antigen class-I (HLA-I) regulates NK cytotoxicity and function. NK regulation influences on NK/T cell alloreactivity…
2015 American Transplant Congress
In House Oxygen Persufflation of Cold Stored Livers Versus Simple Cold Storage in Extended Criteria Liver Grafts: Results of a Randomized Controlled Clinical Trial
A. Gallinat,¹ A. Paul,¹ D. Hoyer,¹ C. Klein,¹ S. Swoboda,¹ C. Ose,² Z. Mathe,¹ J. Treckmann,¹ T. Minor.³
¹Dept. of General-, Viszeral- und Transplantation Surgery, University Hospital Essen, Essen, Germany; ²Institute of Computer Science in Medicine, Biostatistics and Epidemiology, University Hospital Essen, Essen, Germany; ³Surgical Research Div., Universiy Clinic Surgery, Bonn, Germany.
Two hours of end-ischemic oxygen persufflation of cold stored porcine livers regenerates cellular energy dependent pathways and improves survival after transplantation. The present trial evaluated…
2015 American Transplant Congress
Early Recurrence of Primary Sclerosing Cholangitis After Liver Transplantation Has No Negative Impact on Patients outcome'
B. Lowry,¹ W. El Moghazy,^1,2 G. Meeberg,¹ N. Kneteman.¹
¹Hepatobiliary Pancreatic Surgery and Transplantation, University of Alberta, Edmonton, AB, Canada; ²Surgery, Sohag University, Sohag, Egypt.
Liver transplantation (LT) is the only therapeutic option for primary sclerosing cholangitis (PSC), however, recurrence of PSC (rPSC) post-LT occurs at rates ranging from 9-47%.…
2015 American Transplant Congress
Significant Reduction in TRAIL-Expressing NK Cells in Remnant Liver After Partial Hepatectomy Is Strongly Associated With the Impaired Intrahepatic CXCL9–CXCR3 Pathway
T. Yano, M. Ohira, H. Ohdan.
Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima City, Japan.
Antitumor activity of liver natural killer (NK) cells decreases after partial hepatectomy or liver transplantation (LT), suggesting the susceptibility of patients with depressed immune status…