Articles tagged "Liver transplantation"

2022 American Transplant Congress
Ethnic Variation in Adult and Pediatric Liver Transplantation
N. Kemmer¹, M. Malespin¹, S. Agrawal¹, R. Syed¹, K. Alkhalloufi¹, B. Alkurdi¹, C. Albers¹, J. Buggs²
¹Tampa General Hospital, Tampa, FL, ²Transplant Surgery, Tampa General Hospital, Tampa, FL
*Purpose: Despite several policy reforms over the years, disparities in the access to solid organ transplantation continues to exist remains a significant barrier to liver…
2022 American Transplant Congress
Organ Transplantation From Donors With Active Sars-cov-2 Infection: The Italian Experience
P. A. Grossi¹, R. Romagnoli², S. Gruttadauria³, M. Colledan⁴, L. De Carlis⁵, S. Martin-Suarez⁶, G. M. Ettorre⁷, F. Parisi⁸, F. Di Benedetto⁹, U. Maggiore¹⁰, G. Tisone¹¹, E. Andorno¹², M. Carmellini¹³, L. G. Lupo¹⁴, U. Livi¹⁵, A. Montemurro¹⁶, L. Lombardini¹⁷, M. Cardillo¹⁸
¹Medicine and Surgery, Univ degli Studi dell'Insubria, 21100 Varese, Italy, ²Liver Transplant Center -General Surgery 2U, University of Turin, Torino, Italy, ³Abdominal Surgery and Organ Transplantation Unit, ISMETT, Palermo, Italy, ⁴Medicine and Surgery, Ospedale Papa Giovanni XXIII, 24127 Bergamo, Italy, ⁵CHIRURGIA GENERALE E DEI TRAPIANTI, A.O. Ospedale Niguarda Ca' Granda, 20162 Milano, Italy, ⁶Cardio Thoracic and Vascular Department, University of Bologna S.Orsola - Malpighi, 40138 Bologna, Italy, ⁷Dipartimento Interaziendale Trapianti Silvio Natoli, A.O. San Camillo - Forlanini, 00149 Roma, Italy, ⁸DIPARTIMENTO CARDIOCHIRURGIA CARDIOLOGIA E TRAPIANTO CUORE POLMONE, Ospedale Bambino Gesù, 00165 Roma, Italy, ⁹Medicine and Surgery, AOU Policlinico, 41124 Modena, Italy, ¹⁰Dipartimento di Medicina Generale e Specialistica, Ospedale Maggiore - Parma, 21100 Varese, Italy, ¹¹Chirurgia Generale, A.O.U. Policlinico Tor Vergata, 00133 Roma, Italy, ¹²Dipartimento di Chirurgia, Ospedale Policlinico San Martino, 16132 Genova, Italy, ¹³Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze, A.O.U. Senese - S.M. Alle Scotte, 53100 Siena, Italy, ¹⁴E’mergenza e trapianti di organi, AOU Consorziale Policlinico, 70124 Bari, Italy, ¹⁵Medicine and Surgery, Azienda Sanitaria Universitaria Integrata di Udine, 33100 Udine, Italy, ¹⁶Centro Nazionale Trapianti Operativo, CNT, 00162 Roma, Italy, ¹⁷Medical DirectOR, CNT, 00162 Roma, Italy, ¹⁸General Director, CNT, 00162 Roma, Italy
*Purpose: In the present study we want to report safety and outcome of organ transplantation from donors with active SARS-CoV-2 infection in Italy.*Methods: In November…
2022 American Transplant Congress
The Acuity Circle Allocation Policy is Associated with Worse Graft Survival After Liver Transplant with Donation After Circulatory Death Donors in Low-MELD Centers
T. Kitajima¹, T. Ivanics², D. Moonka¹, M. Shamaa¹, A. Mohamed³, S. Shimada¹, K. Collins⁴, M. Rizzari¹, A. Yoshida¹, M. Abouljoud⁴, S. Nagai¹
¹Henry Ford Hospital, Detroit, MI, ²Surgery, Henry Ford Hospital, Detroit, MI, ³Department of Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI, ⁴Henry Ford Transplant Institute, Detroit, MI
*Purpose: Liver allocation in the United States was updated in February of 2020, with introduction of the acuity circle (AC) model. However, the effect of…
2022 American Transplant Congress
Antibody and Cellular Immunity After Primary mRNA Vaccination in Adolescents with Stable Liver or Liver-Inclusive Intestine Allografts
G. Mazariegos¹, C. Ashokkumar², K. Soltys², M. Michaels², G. Bond², A. Khanna², M. Ningappa², P. Morgan², R. Sindhi²
¹UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, ²Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, PA
*Purpose: Transplant recipients experience lower seroconversion rates after COVID-19 vaccination compared with healthy adults and have been prioritized to receive booster doses. To assess pre-…
2022 American Transplant Congress
Factors Predicting Early Extubation After Liver Transplantation
V. Subramanian¹, O. Bishr², J. Buggs¹, N. Kemmer¹, K. Dhanireddy¹
¹Transplant Institute, Tampa General Hospital, Tampa, FL, ²University of South Florida, Tampa, FL
*Purpose: Early extubation (either intraoperative or within 6 hours post operatively) is an important component of enhanced recovery pathways. The goal of the study was…
2022 American Transplant Congress
Center-Level Variation in Transplantation Practice Following Acuity Circles Policy Change
A. Burton¹, D. Goldberg²
¹University of Miami Miller School of Medicine, Miami, FL, ²Department of Gastroenterology, University of Miami Miller School of Medicine, Miami, FL
*Purpose: Although early studies suggest that the Acuity Circles (AC) allocation policy has reduced disparities in access to deceased donor liver transplants (DDLTs), changes in…
2022 American Transplant Congress
Meld Score <31 Predicts Spontaneous Recovery in Patients Listed for Liver Transplantation for Alcohol-Associated Hepatitis: A UNOS Database Study
Y. Bekki, G. Im, T. Schiano, S. Florman
Icahn School of Medicine at Mount Sinai, RMTI, New York, NY
*Purpose: Alcohol-associated hepatitis (AH) is the fastest growing indication for liver transplantation (LT) in the U.S. While spontaneous recovery (SR) can occur in patients with…
2022 American Transplant Congress
Artificial Intelligence Based Dosing of Tacrolimus in Liver Transplantation: Prospective, Randomized Phase 2 Trial
A. Zarrinpar¹, C. Ho², C. Warren¹, J. Khong², M. Lee², S. Duarte¹, K. Andreoni¹, M. Johnson¹, N. Battula³, D. McKimmy¹, T. Beduschi¹
¹Surgery, University of Florida, Gainesville, FL, ²Mechanical and Aerospace Engineering, University of California, Los Angeles, CA, ³Surgery, University of Oklahoma, Oklahoma City, OK
*Purpose: Inter- and intra-individual variability in calcineurin dose requirements necessitates empirical clinician-titrated dosing that frequently results in deviation from target ranges, particularly during the critical…
2022 American Transplant Congress
Post-Operative Day 1 Galectin-3 is Predictive of Early Allograft Dysfunction in Liver Transplantation
D. Yoeli, T. Ferrell, I. Rodriguez, N. Limon De La Rosa, N. Nakra, Z. Wang, E. Cervantes-Alvarez, R. Choudhury, M. Adams, T. Nydam, E. Pomfret, C. Huang, N. Navarro Alvarez, H. Moore
University of Colorado Anschutz Medical, Aurora, CO
*Purpose: Early allograft dysfunction (EAD) is an important outcome measure in liver transplantation that is predictive of graft failure, but the mechanism behind it remains…
2022 American Transplant Congress
Detection of Early Graft Injury After Liver Transplantation with Blood-Bile Ratio of Tacrolimus: The TUBE Trial
M. M. Pascale¹, G. Bianco¹, L. Ferri¹, F. Giovinazzo¹, A. Liguori², G. Marrone², A. Grieco², S. Agnes¹
¹General Surgery and Liver Transplant Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy, ²Transplant Hepatology Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy
*Purpose: The aim of the“Tacrolimus in Bile”(TUBE)Trial is the creation of a laboratory parameter for the early detection of hepatic injury after liver transplant.*Methods: TUBE…