Articles tagged "Liver transplantation"

2015 American Transplant Congress
Myeloid Cell-Specific Heme Oxygenase-1 Is Crucial for Hepatoprotection in Liver Ischemia-Reperfusion Injury
K. Nakamura,¹ M. Zhang,² B. Ke,¹ R. Busuttil,¹ J. Araujo,² J. Kupiec-Weglinski.¹
¹Surgery, Liver Transplant, University of California, Los Angeles, Los Angeles, CA; ²Medicine, Division of Cardiology, University of California, Los Angeles, Los Angeles, CA.
Background and Aim: Heme oxygenase-1 (HO-1), an anti-oxidant enzyme, is essential in tissue resistance against innate immunity driven ischemia-reperfusion injury (IRI). Our group was the…
2015 American Transplant Congress
Modified Upper Abdominal Organ Cluster Transplantation: A Serial of 16 Cases in a Single Center
J. Zhou, W. Ju, X. Yuan, D. Wang, X. Zhu, X. He.
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Objectives: Various postoperatively complications and high mortality rate are the major difficulties in early classical total and subtotal abdominal organ transplantation. To improve long-term survival,…
2015 American Transplant Congress
Determinants and Sequelae of Hepatic Artery Thrombosis After Liver Transplantation: A Registry Study of Recipient Diagnosis and Coagulopathy
J. Garonzik Wang,¹ M. Doyle,¹ K. Collins,¹ J. Lowell,¹ Y. Lin,¹ S. Shenoy,¹ J. Wellen,¹ W. Chapman,¹ D. Segev.²
¹Washington University, Barnes Jewish Hospital, Saint Louis, MO; ²Johns Hopkins University, Johns Hopkins Hospital, Baltimore, MD.
Hepatic artery thrombosis (HAT) is a dreaded complication following liver transplantation. Despite improvements in technique and procurement, HAT still occurs in approximately 2-5% of recipients.…
2015 American Transplant Congress
Outcomes of HIV+ Liver Transplant Recipients Compared to HCV+ or HIV+/HCV+ Co-Infected Recipients: The “Real World” Experience
D. Sawinski,¹ G. David,² E. Blumberg,³ P. Abt,⁴ R. Bloom,¹ K. Forde.²
¹Renal Division, Univ. of Penn, Philadelphia, PA; ²Gastroenterology Division, Univ. of Penn, Philadelphia, PA; ³Infectious Disease, Univ. of Penn, Philadelphia, PA; ⁴Surgery, Univ of Penn, Philadelphia, PA.
End stage liver disease is a frequent cause of mortality in patients with HIV. Though demonstrated in the NIH observational trial, the effectiveness of LT…
2015 American Transplant Congress
Rabbit Antithymocyte Globulin Is Associated With Improved Patient and Graft Survival in Liver Transplantation. Experience With 595 Patients
M. Montenovo,¹ F. Jalikis,² L. Meng,³ Y. Matthew,² D. Andre,¹ H. Ryan,³ R. Jorge.¹
¹Surgery, University of Washington, Seattle, WA; ²Pathology, University of Washington, Seattle, WA; ³Pharmacy, University of Washington, Seattle, WA.
BACKGROUND: Use of induction therapy in liver transplantation is debatable. We aimed to compare clinical outcomes of different induction protocols in liver transplant recipients.METHODS: Retrospective…
2015 American Transplant Congress
Normothemic Machine Perfusion of Liver Grafts Promotes Liver Regeneration and Inhibits Tissue Inflammation
E. Xystrakis, J. Lozano, R. Danger, M. Martinez-Llordella, P. Srinivasan, N. Heaton, C. Coussios, A. Sanchez-Fueyo, Y. Ma, W. Jassem.
Institute of Liver Studies, King's College London School of Medicine at King's College Hospital, London, United Kingdom; Plataforma de Bioinformatica, Centro de Investigación Biomédica en red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clinic, Centre Esther Koplovitz (CEK), Barcelona, Spain; Nuffield Department of Surgical Sciences, Oxford University, Oxford, United Kingdom.
Background & aim: liver transplantation I/R injury is associated with inflammation, affecting graft outcome. Ex-vivo normothermic machine perfusion (NMP) to donor livers before transplantation reduces…
2015 American Transplant Congress
The Effect of Preformed and De Novo Donor-Specific Antibodies (DSA) in Acute Rejection (AR) After Liver Transplantation (LTX)
M. Koch,¹ M. Runnebaum,¹ M. Goebel,² H. Thude,¹ M. Sterneck,¹ M. Marget,² B. Nashan.¹
¹Hepatobiliary Surgery and Transplantation, University Medical Centre, Hamburg, Germany; ²HLA-Laboratory, University Medical Centre, Hamburg, Germany.
BACKGROUND: The role of preformed and den novo formed DSA in LTX is not fully revealed. The aim of our study was to determine if…
2015 American Transplant Congress
Financial Impact of an Advanced Liver Disease Service on a Tertiary Health System
A. Masoumi,¹ S. Hanish,² J. LaMattina,² C. Njoka,¹ W. Hutson,² D. Potosky,² R. Barth.²
¹University of Maryland Medical Center, Baltimore; ²University of Maryland School of Medicine, Baltimore.
Regional disparities in liver transplantation motivated revision of national organ-sharing policies towards critically ill patients. Liver transplantation of high MELD patients incorporates significant institutional commitment…
2015 American Transplant Congress
The Product of Donor Age and Preoperative MELD, D-MELD, Predicts Surgical Outcomes After LDLT, When Using Small Graft
A. Tanemura, S. Mizuno, H. Kato, Y. Murata, N. Kuriyama, Y. Azumi, M. Kishiwada, M. Usui, H. Sakurai, S. Isaji.
Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Background:Donor-recipient match is recognized as the factor well predicting recipient outcome in deceased donor liver transplantation. The aim of the present study is to evaluate…
2015 American Transplant Congress
Historical Comparison of Projected and Observed Liver Transplants
J. Pyke,¹ D. Schladt,¹ W. Kim,⁵ S. Leppke,¹ J. Lake,⁴ S. Gentry,^2,3 D. Segev,² A. Israni,¹ J. Snyder.¹
¹SRTR, Minneapolis Medical Research Foundation, Minneapolis, MN; ²Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; ³Mathematics, US Naval Academy, Baltimore, MD; ⁴Medicine and Surgery, University of Minnesota Medical School, Minneapolis, MN; ⁵School of Medicine, Stanford University, Stanford, CA.
We aimed to compare liver transplant simulation projections to observed data before and after a major policy update. The current liver simulated allocation model (LSAM…