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American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2015 American Transplant Congress

    Are We Missing Cardiovascular Disease in Children Awaiting Liver Transplant?

    C. Villa,1 E. Hahn,1 J. Bucuvalas,2 K. Campbell,2 R. Hirsch,1 M. Lake,2 A. Lorts.1

    1Heart Institute, Cincinnati Childrens Hospital, Cincinnati, OH; 2Pediatric Liver Care Center, Cincinnati Childrens Hospital, Cincinnati, OH.

    Background: Cirrhotic cardiomyopathy, characterized by low systemic vascular resistance, is increasingly recognized as a complication of end stage liver disease. Yet optimal strategies to screen…
  • 2015 American Transplant Congress

    Pediatric Liver Transplantation for Metabolic Diseases: Analysis of Children's Hospital of Pittsburgh (CHP) and United Network for Organ Sharing (UNOS) Databases

    A. Ganoza, B. Shneider, R. Sindhi, K. Soltys, G. Bond, G. Vockley, Q. Sun, G. Mazariegos.

    Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

    Purpose: To analyze long term patient survival outcomes after primary LTx for metabolic disease in children <21 years at CHP (1981-2014) and the multi-center UNOS…
  • 2015 American Transplant Congress

    Iron Deficiency Impairs Regulatory T Cell Induction

    R. Danger,1 E. Bonaccorsi-Riani,1 E. Kodela,1 H. Collins,2 R. Hider,3 M. Martínez-Llordella,1 A. Sánchez-Fueyo.1

    1Department of Liver Sciences, Faculty of Life Sciences & Medicine, MRC Transplant Centre, King's College London, London, United Kingdom; 2Department of Immunology, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom; 3Institute of Pharmaceutical Science, King's College London, London, United Kingdom.

    In a recent clinical trial of immunosuppression withdrawal in adult liver transplant recipients, operational tolerance was associated with development of a transient lymphocyte infiltration rich…
  • 2015 American Transplant Congress

    Ischemic Cholangiopathy Following Liver Transplantation from Donation After Circulatory Death Donors: Role of Tissue Plasminogen Activator Flush

    C. Kubal,1 R. Mangus,1 J. Fridell,1 M. Wingler,2 S. Nagai,1 B. Ekser,1 J. Tector.1

    1Department of Surgery, Indiana University, Indianapolis, IN; 2Indiana Organ Procurement Organization, Indianapolis, IN.

    Background: Formation of microthrombi within the peribiliary arterial plexus causing necrosis of biliary epithelium may be responsible for ischemic cholangiopathy (IC) after donation after circulatory…
  • 2015 American Transplant Congress

    Impact of Pretransplant Sarcopenia and Sequential Changes in Sarcopenic Parameters After Living Donor Liver Transplantation

    T. Kaido,1 Y. Tamai,2 K. Ogawa,1 Y. Fujimoto,1 A. Mori,1 H. Okajima,1 N. Inagaki,2 S. Uemoto.1

    1Hepato-Biliary-Pancreatic and Transplant Surgery, Kyoto University, Kyoto, Japan; 2Metabolism and Clinical Nutrition, Kyoto University Hospital, Kyoto, Japan.

    The present study investigated the impact of pretransplant sarcopenia on survival and sequential changes in sarcopenic parameters in patients undergoing living donor liver transplantation (LDLT).…
  • 2015 American Transplant Congress

    HCV Treatment in Liver Transplantation: Changes in Center Attitudes and Practices in the DAA Era

    A. Shaffer, A. Cash, S. Anjum, D. Segev, C. Durand.

    Surgery, Johns Hopkins University, Baltimore, MD.

    Chronic hepatitis C virus infection (HCV) is the leading indication for liver transplantation (LT) in the US. Safe and effective directly acting antivirals (DAAs) are…
  • 2015 American Transplant Congress

    Hepatic T Cells Derived from Normothemic Machine Perfused Grafts Contained More Regulatory T Cells and Fewer Proinflammatory Cytokines Producing T Cells Than Those from Cold Storage Grafts

    X. Huang, R. Ravikumar, C. Coussios, P. Srinivasan, N. Heaton, P. Friend, W. Jassem, Y. Ma.

    1Institute of Liver Studies, King's College London School of Medicine at King's College, London, United Kingdom; Nuffield Department of Surgical Sciences, Oxford University, Oxford, United Kingdom.

    Background & aim:In liver transplantation, ischemia reperfusion (I/R) injury is associated with an inflammatory response affecting graft and patient outcomes. Ex-vivo normothermic machine perfusion (NMP)…
  • 2015 American Transplant Congress

    Liver Flushing Using Colloid and Crystalloid Solutions

    J. Burg, D. Scott, K. Enestvedt, K. Roayaie, D. Scott.

    Abdominal Organ Transplantation, Oregon Health and Science University, Portland.

    Background:Preservation solutions such as University of Wisconsin solution and histidine-tryptophan-ketoglutarate solution have been cited as causes of hypotension and adverse donor reactions following reperfusion of…
  • 2015 American Transplant Congress

    Liver Fabrication Using Whole Organ Scaffold for Transplantable Graft in Large Animal

    K. Inomata,1 H. Yagi,1 K. Tazima,1 K. Sugiyama,1 M. Hieda,1 T. Hibi,1 Y. Abe,1 M. Kitago,1 M. Shinoda,1 O. Itano,1 T. Akaike,2 Y. Kitagawa.1

    1Surgery, Keio University, Tokyo, Japan; 2Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Tokyo, Japan.

    Background and aims: Orthotopic liver transplantation is only effective treatment for end-stage liver disease, however it is limited by shortage of donor livers. Therefore, novel…
  • 2015 American Transplant Congress

    Nonalcoholic Steatohepatitis as Indication for Liver Transplantation in Europe. Do We Choose the Right Organs for the Right Recipients?

    B. Kern,1 P. Newsome,2 V. Karam,3 R. Adam,3 G. Berlakovich,4 J. Fritz,5 W. Popp,1 B. Feurstein,1 A. Pascher,6 P. Muiesan,7 S. Schneeberger.1

    1Visceral- Transplant, Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria; 2NIHR Biomedical Research Unit and The Centre for Liver Research, University of Birmingham, Birmingham, United Kingdom; 3Hepatobiliary Center, Paul Brousse Hospital - Hôpitaux de Paris Université Paris-Sud, Villejuif, France; 4Transplant Surgery, Medical University of Vienna, Vienna, Austria; 5Medical Statistics, Innsbruck Medical University, Innsbruck, Austria; 6General, Visceral, Transplant Surgery, Charite Berlin, Berlin, Germany; 7Liver and Hepato-Pancreato-Biliary Unit, University of Birmingham, Birmingham, United Kingdom.

    Background:Nonalcoholic steatohepatitis (NASH) has emerged to become the third leading cause for liver transplantation (LT) in the US and since 2002, it has increased constantly.Methods:We…
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