ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2016 American Transplant Congress

    Influence of Donor and Recipient CYP3A4, CYP3A5 and ABCB1 Genotypes on Outcomes in Liver Transplants.

    M. Debette-Gratien,1 J. Woillard,2 N. Picard,2 M. Sebbagh,4 D. Sautereau,5 V. Loustaud-Ratti,1 D. Samuel,3 P. Marquet.2

    1Hepatology, INSERM UMR 850, Univ Limoges, CHU Limoges, Limoges, France; 2Pharmacology and Toxicology, INSERM UMR 850, Univ Limoges, CHU Limoges, Limoges, France; 3Hepatology, INSERM U785, Centre hépatobiliaire, Villejuif, France; 4Hepatology, Centre Hépatobiliaire, Villejuif, France; 5Hepatology, CHU Limoges, Limoges, France.

    Liver transplantation is a life-saving technique for patients with end-stage liver disease. Pharmacogenetics is promising to explain a part of variability of calcineurin inhibitors efficacy…
  • 2016 American Transplant Congress

    Use of En-Bloc Vascularized Rectus Sheath Allograft to Achieve Abdominal Closure in Pediatric Liver and Multivisceral Transplantation.

    J. Reddy, A. Rege, D. Vikraman, B. Collins, T. Brennan, S. Knechtle, D. Sudan, K. Ravindra.

    Surgery, Duke University, Durham, NC.

    Background: Abdominal wall closure is often challenging in pediatric liver (LT) and multivisceral transplantation (MVT) due to size discrepancy of donor & recipient and abdominal…
  • 2016 American Transplant Congress

    Sofosbuvir-Based Regimen in Treatment Experienced-Post Liver Transplant Patients with Hepatitis C Recurrence.

    A. Ajlan,1 A. Aljedai,1 H. Elsiesy,2 D. Alkortas,1 R. Alarieh,2 W. Alhumodi,2 D. Broring,2 M. Alsebayel,2 F. Aba Alkhail.2

    1Pharmaceutical Care, KFSHRC, Riyadh, Saudi Arabia; 2Liver and Small Bowel Transplant, KFSHRC, Riaydh, Saudi Arabia.

    This is an open label, prospective, interventional cohort study conducted at a tertiary referral center. The primary end point is SVR12 in patients treated with…
  • 2016 American Transplant Congress

    Share35 Liver Allocation Is Associated with Increased Early Graft Failure Rate.

    T. Wong,1 N. Koizumi,2 J. Ortiz.3

    1Maricopa Medical Center, Phoenix, AZ; 2George Mason University, Arlington, VA; 3University of Toledo, Toledo, OH.

    Background: The implementation of Share35 liver allocation policy in June 2013 facilitated the increase in number of transplanted livers with less organ discards. Early analysis…
  • 2016 American Transplant Congress

    Impact of Early Allograft Dysfunction (EAD) and Its Components on Patient Survival Following Liver Transplantation (LT): Long-Term Outcomes Up to 10 Years.

    B. Ekser, R. Mangus, J. Fridell, C. Kubal, J. Davis, J. Salisbury, T. Salisbury, S. Nagaraju, P. Mihaylov, A. Tector.

    Transplant Division, Department of Surgery, Indiana University, Indianapolis, IN.

    Background: It has been shown that EAD in LT is a useful tool to predict intermediate (5-year) mortality. The purpose of this study is to…
  • 2016 American Transplant Congress

    Mothers Are Often Sensitized and Sensitive: Antibody Mediated Rejection in Child to Mother Living Donor Liver Transplantation.

    B. Movahedi,1 N. Yu,2 P. Martins,1 A. Ahearn,1 J. Stoff,1 A. Bozorgzadeh.1

    1Division of Organ Transplantation, UMass Memorial Medical Center, Worcester, MA; 2Clinical Pathology, Histocompatibility Laboratory, UMass Memorial Medical Center, Worcester, MA.

    Background: Partial graft is especially more vulnerable to deleterious effects of donor specific HLA antibodies (DSA). Living liver donors and recipients are often family members.…
  • 2016 American Transplant Congress

    Occult Multifocal Hepatocellular Carcinoma in Surgical Patients.

    D. Aufhauser Jr,1 E. Sadot,2 D. Murken,1 K. Eddinger,1 D. Goldberg,3 E. Furth,4 P. Abt,1 R. DeMatteo,2 M. Levine.1

    1Surgery, University of Pennsylvania, Philadelphia, PA; 2Surgery, Memorial Sloan Kettering Cancer Center, New York, NY; 3Medicine, University of Pennsylvania, Philadelphia, PA; 4Pathology, University of Pennsylvania, Philadelphia, PA.

    Introduction: Resection of hepatocellular carcinoma (HCC) is associated with high rates of intrahepatic recurrence. However, it is unclear whether recurrence results from occult multifocal disease…
  • 2016 American Transplant Congress

    A Multi-Center Study of Factors That Increase Cognitive Load in Living Donor Liver Transplants.

    A. Lee,1 R. Khorzad,1 E. Pomfret,2 J. Guarrera,3 R. Fisher,4 M. Simpson,2 A. Skaro,1 A. Daud,1 N. Salehitezangi,1 D. Woods,1 D. Ladner.1

    1Northwestern University, Chicago, IL; 2Lahey Clinic, Burlington, MA; 3Columbia University, New York, NY; 4Virginia Commonwealth Univeristy, Richmond, VA.

    Background: Studies have shown that distractions in the operating room (such as phones/pagers, irrelevant conversations, ins and outs) can negatively affect concentration and performance, and…
  • 2016 American Transplant Congress

    Liver Recipient with Renal Dysfunction: Liver Only or Simultaneous Liver-Kidney Transplant?

    K. Yadav, T. Pruett, R. Kandaswamy, W. Payne, L. Zhang, S. Chinnakotla.

    University of Minnesota, Minneapolis, MN.

    Background: The OPTN listing criteria for Simultaneous liver-kidney transplant (SLK) are not well defined. There are concerns about rising numbers of SLKs, which take kidneys…
  • 2016 American Transplant Congress

    Outcomes of Living and Deceased Donor Liver Transplant Recipients According to the MELD Score.

    J. Lee, J. Lee, S. Song, J. Lee, S.-K. Kwon, D. Joo, M. Ju, G. Choi, J. Choi, S. Kim, M. Kim.

    Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.

    BackgroundLiving donor liver transplantation (LDLT) has developed as an alternative to decease donor liver transplantation (DDLT) to overcome the critical shortage of deceased organ donations.…
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