2022 American Transplant Congress
Chimeric Antigen Receptor Regulatory T Cells (CAR-Tregs) Provide Significantly Greater Modulation of Alloimmune Responses Than Alternative Alloantigen-Specific Treg Strategies
1King's College London, London, United Kingdom, 2Quell Therapeutics, London, United Kingdom
*Purpose: Conferring alloantigen-specificity to ex vivo expanded CD4+CD25+Foxp3+ Tregs increases their capacity to counteract effector alloimmune responses following adoptive transfer into transplant recipients. This has…2022 American Transplant Congress
The Limited Role of Liver Transplantation in Porto-Pulmonary Hypertension Pathology
*Purpose: Portopulmonary hypertension (POPH) refers to pulmonary artery hypertension (PH) as a consequence of portal hypertension with or without liver disease. Previous studies used pulmonary…2022 American Transplant Congress
Covid-related Neonatal Cholestasis?: Liver Transplantation In Three Infants With Intrauterine Or Perinatal Covid Exposure
1Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine, Houston, TX
*Purpose: The COVID pandemic presents a unique set of challenges during pregnancy including thromboembolic complications, direct placental infection, transplacental transmission, and systemic hyperinflammatory state. The…2022 American Transplant Congress
T Cell-Specific CEACAM1 Alleviates Posttransplant Liver Injury via TIM-3 Inhibitory Regulation
UCLA Medical Center, Los Angeles, CA
*Purpose: Carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1; CC1), a recently discovered ligand for T cell immunoglobulin domain and mucin domain-3 (TIM-3) on activated T…2022 American Transplant Congress
Is Remnant Liver Volume Ratio Less Than 30% Still Contraindication to Right Hepatectomy for Living Liver Donors?
Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea, Republic of
*Purpose: Recently, some centers reported that extended resection with remnant/total volume ratio(RTVR) less than 30% for living donor right hepatectomy(LDRH) but there is no consensus…2022 American Transplant Congress
The Role of Gastrointestinal Pathogen PCR Testing in Liver Transplant Recipients Hospitalized with Diarrheal Illness
*Purpose: Diarrhea is a common complication among liver transplant (LT) recipients and can result in significant morbidity. The development of PCR-based multiplex gastrointestinal (GI) pathogen…2022 American Transplant Congress
Impact of Donor-to-Recipient Body Surface Area Ratio on Graft Survival and Mortality Following Deceased Donor Liver Transplants
Surgery, Johns Hopkins University, Baltimore, MD
*Purpose: The impact of size mismatch on graft survival in living donor liver transplant is well established but is not a common concern in deceased…2022 American Transplant Congress
Increased Use of DCD Liver Grafts Does Not Adversely Affect Outcomes: A Single-Center Experience
Baylor University Medical Center/Baylor Simmons Transplant Institute, Dallas, TX
*Purpose: Donation after circulatory death (DCD) donors are underutilized in liver transplantation (LT), partly due to fear of inferior outcomes. Our center has evolved from…2022 American Transplant Congress
Left Ventricular Diastolic Dysfunction: Prevalence and Relation to Outcomes in Liver Transplantation Recipients
1University of Maryland, Baltimore, MD, 2University of Maryland School of Medicine, Baltimore, MD
*Purpose: Assess the prevalence and characteristics of patients with pre-transplant left ventricular diastolic dysfunction (LVDD) and its potential impact on post-transplant morbidity and mortality.*Methods: Retrospective…2022 American Transplant Congress
Liver Transplantation in Patients with Portal Vein Thrombosis: Implications and Outcomes
Liver and Pancreas Transplant Center, UCLA, Los Angeles, CA
*Purpose: Preoperative bland portal vein thrombosis (PVT) is common in Liver transplant (LT) candidates and has been suspected to negatively impact post-LT outcomes, however studies…
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