Articles tagged "Liver transplantation"

2016 American Transplant Congress
High Efficacy of Ledipasvir/Sofosbuvir with Ribavirin in HCV Genotype-1 Infected Patients with Decompensated Liver Disease: Analysis by MELD Score from the SOLAR-1 and SOLAR-2 Trials.
M. Charlton,¹ E. Yoshida,² M. Bouliere,³ S. Flamm,⁴ A. Muir,⁵ M. Fried,⁶ N. Terrault,⁷ S. Arterburn,⁸ C. Yun,⁸ P. Pang,⁸ A. Osinusi,⁸ J. Spellman,⁸ M. Natha,⁸ D. Brainard,⁸ J. McHutchison,⁸ M. Manns,⁹ N. Afdhal.¹⁰
¹Intermountain Medical Center, Salt Lake City; ²Vancouver General Hospital, Vancouver, Canada; ³Hopital Saint Joseph, Marseilles, France; ⁴Northwestern University, Chicago; ⁵Duke University, Durham; ⁶University of North Carolina, Chapel Hill; ⁷UCSF, SF; ⁸Gilead Sciences Inc, Foster City; ⁹Hannover Medical School, Hannover, Germany; ¹⁰BIDMC, Boston.
Introduction: HCV infected patients with decompensated liver disease have significant morbidity & mortality. The efficacy & safety of LDV/SOF + RBV was evaluated in a…
2016 American Transplant Congress
Pretransplant Serum Hyaluronic Acid Can Be a Prognostic Predictor in Adult-to-Adult Living Donor Liver Transplantation.
S. Mizuno,¹ B. Das,² Y. Iizawa,¹ H. Kato,¹ Y. Murata,¹ A. Tanemura,¹ N. Kriyama,¹ Y. Azumi,¹ M. Kishiwada,¹ M. Usui,¹ H. Sakurai,¹ S. Isaji.¹
¹Hepatobiliary-Pancreatic and Transplant Surgery, Mie University, Tsu, Japan; ²Hepatobiliary Pancreatic Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Objectives:Recently, hyaluronic acid (HA) levels of the solution during graft preservation has been reported to be associated with primary non function in deceased donor liver…
2016 American Transplant Congress
Transplants without Borders – A Project for In Locus Training of New Transplants Centers in Brazil.
M. Perosa,¹ J. Branez,¹ L. Mota,¹ B. Zeballos,¹ H. Noujaim,¹ L. Ianhez,¹ L. Alvim,¹ D. Machado,¹ M. Moreno,¹ T. Genzini,¹ R. Kandaswamy.²
¹Transplant Department, Bandeirantes Hospital, Sao Paulo, SP, Brazil; ²Transplant, Univ Minnesota, Minneapolis, MN.
The regional disparity in transplant activity is a huge problem in Brazil and in other countries. Brazilian transplant centers are concentrated in the coastal states,…
2016 American Transplant Congress
Fifty Is the New 40? An Argument to Uncap the MELD Score.
J. DiNorcia,¹ Y. Genyk,¹ K. Andreoni,⁴ W. Kim,³ J. Levitsky,⁵ D. Mulligan,⁶ R. Sung,⁷ M. Nadim.¹
¹Univ of Southern California, Los Angeles, CA; ²Stanford University, Palo Alto, CA; ³Univ of Florida, Gainesville, FL; ⁴Northwestern Univ, Chicago, IL; ⁵Yale Univ, New Haven, CT; ⁶Univ of Michigan, Ann Arbor, MI.
Background: The MELD score is used to prioritize patients awaiting liver transplantation (LT) and has been capped at 40 to prevent transplant futility in patients…
2016 American Transplant Congress
Long-Term Liver Function of Deceased Liver Transplantation Using Hepatitis B Surface Antigen Positive Grafts.
W.-C. Lee,¹ Y.-C. Wang,¹ C.-H. Cheng,¹ T.-H. Wu,¹ C.-F. Lee,¹ R.-S. Soong,¹ T.-J. Wu,¹ H.-S. Chou,¹ K.-M. Chan,¹ C.-S. Lee.²
¹Liver and Transplantation Surgery, Chang-Gung Memorial Hospital, Taoyuan, Taiwan; ²Hepatology, Chang-Gung Memorial Hospital, Taoyuan, Taiwan.
Background: Deceased donors with hepatitis B [HBs Ag(+)] were not recommended to recover the livers for liver transplantation. However, in endemic area of hepatitis B…
2016 American Transplant Congress
Tipping the Scales: Liver Transplant Outcomes of the Super Obese.
R. Gedaly, J. Berger, X. Mei, F. Marti, L. Turcios, M. Shah.
Surgery, University of Kentucky, Lexington.
Objective: We aim to study outcomes in liver transplant recipients with BMI >50 using the UNOS database.Methods: We reviewed patients undergoing liver transplantation recorded in…
2016 American Transplant Congress
Decellularized Rat Liver Scaffolds Support Multilineage Xenogenic and Heterogenic Cell Growth.
W. Hassanein, U. Dhru, J. Woodall, M. Uluer, A. Cimeno, D. Parsell, C. Rivera, S. Klepfer, C. Drachenberg, R. Barth, J. LaMattina.
University of Maryland School of Medicine, Baltimore, MD.
Background:Recent years have seen a proliferation of methods leading to successful organ decellularization. Nonetheless, the ability to reproducibly generate a robust recellularized construct remains challenging.…
2016 American Transplant Congress
When Liver Transplants and Procurement Occur at One Location – A National Study of Graft Survivals.
J. Ortiz,¹ N. Koizumi,² C. Kwon,² Y. Zhang,² C. Ortiz.³
¹University of Toledo, Toledo, OH; ²George Mason University, Fairfax, VA; ³Bucknell University, Lewisburg, PA.
Organ procurement and placement processes entail complex scheduling, logistics and other administrative challenges, especially when organs travel outside the procuring Organ Procurement Organization (OPO) area.…
2016 American Transplant Congress
Factors in a Successful Transfer of Pediatric Liver Transplant Recipients to Adult-Based Care.
J. Bilhartz, M. Lopez, J. Magee, V. Shieck, S. Eder, E. Fredericks.
University of Michigan, Ann Arbor.
Purpose: A structured shift in allocation of responsibility (AoR) for health-management tasks from parents to adolescents is an important component of the transfer to adult-based…
2016 American Transplant Congress
Assessing the Impact of the Share35 Liver Allocation Policy: Survival Outcomes Among Liver Re-Transplant Recipients.
J. Ortiz,¹ N. Koizumi,² C. Kwon,² Y. Zhang,² C. Ortiz.³
¹Department of Surgery, University of Toledo, Toledo, OH; ²George Mason University, Fairfax, VA; ³Bucknell University, Lewisburg, PA.
Liver retransplantation (reLTx) is the only treatment option for those who experienced graft loss after primary liver transplantation (LTx). Yet, in an era of increasing…