Articles tagged "Liver transplantation"

2016 American Transplant Congress
Sphingosine-1 Phosphate Receptor 1 Agonist SEW2871 Ameliorates Hepatocellular Injury on Ischemic Reperfusion in Mice: A New Therapeutic Target.
T. Ito, N. Kuriyama, A. Matsuda, H. Kato, Y. Iizawa, Y. Murata, A. Tanemura, Y. Azumi, M. Kishiwada, S. Mizuno, M. Usui, H. Sakurai, S. Isaji.
Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu City, Mie, Japan.
Introduction: We had reported that activated protein C (APC) administration had cytoprotective effects on hepatic ischemic reperfusion (IR) injury in rat and mice models. Recent…
2016 American Transplant Congress
Review of Aborted Hepatectomy of Liver Transplantation in a Single Center Study.
J. Lee, G. Choi, W. Cho, J.-W. Joh, S.-K. Lee, S.-J. Kim, C. Kwon, J. Park, J. Kim.
General Surgery, Samsung Medical Center, Seoul, Korea.
Liver transplantation (LT) has become a popular option for the treatment of endstage hepatic failure. More attention has been given to donor safety, but still…
2016 American Transplant Congress
Renal Outcomes of Pediatric Kidney Transplant Recipients Following a Previous Solid Organ Transplantation.
G. Hamdani,¹ B. Zhang,² J. Goebel,³ E. Nehus.¹
¹Division of Nephrology & Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; ²Center for Epidemiology & Biostatistics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; ³Nephrology, Children's Hospital Colorado, Aurora, CO.
Purpose: We aimed to study the renal outcomes of pediatric kidney transplant recipients following a previous non-renal solid organ transplantation (SOT).Methods: A retrospective analysis of…
2016 American Transplant Congress
Conversion to Once-Daily Tacrolimus in Stable Pediatric Liver Transplantation Recipients.
N. Lee, S. Lee, C.-W. Cho, J. Lee, J. Lee, J. Kim, G.-S. Choi, C. Kwon, J.-W. Joh, S.-K. Lee.
Department of Surgery Organ Transplant Center, Samsung Medical Center, Seoul, Republic of Korea.
Purpose: Pediatric patients are known to have lower compliance than adult patients. Once-daily formulation of tacrolimus may increase compliance in pediatric liver transplant recipients. The…
2016 American Transplant Congress
Virological Response at 4 Weeks With a Sofosbuvir-Based Antiviral Regimen in Liver Transplant Recipients with Recurrent Hepatitis C.
T. Pastrana-Camacho,¹ M. Bradley,¹ H. Winters,¹ S. Black,² K. Porter,³ K. Mumtaz.⁴
¹Pharmacy, The Ohio State University-Wexner Medical Center, Columbus, OH; ²Department of Surgery, The Ohio State University-Wexner Medical Center, Columbus, OH; ³Center for Biostatistics, The Ohio State University-Wexner Medical Center, Columbus, OH; ⁴Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, The Ohio State University-Wexner Medical Center, Columbus, OH.
Background: The literature is growing in the area of safety, efficacy and tolerability of sofosbuvir (SOF)- based antivirals therapy (AVT) in recurrent hepatitis C virus…
2016 American Transplant Congress
Improving the Efficiency, Safety and Cost of Evaluating Living Donor Liver Candidates Using Single Sequence MRI.
M. Schilsky,^1,2 K. Cartiera,¹ S. Boga,¹ S. Schilsky,³ S. Emre,¹ D. Mulligan,¹ J. Weinreb,¹ G. Israel.¹
¹Yale New Haven Transplantation Center, Transplantation and Immunology, Surgery, Yale University, New Haven, CT; ²Section of Digestive Diseases, Medicine, Yale University, New Haven, CT; ³Food and Drug Administration, Silver Springs, MD.
Background: Current evaluation of donor candidates for adult-to-adult living donor liver transplant (LDLT) includes MRI and CT without and with contrast for defining liver anatomy.…
2016 American Transplant Congress
What Are the Charges and Costs of Transplanting High MELD Patients?
K. Bortecen, B. Gelb, A. Winnick, G. Morgan, L. Teperman.
Transplant Surgery, NYU Langone Medical Center, New York, NY.
Purpose: There is a significant variation in the MELD scores and subsequent morbidity among liver recipients in the US. Larger OPOs consistently serve patients with…
2016 American Transplant Congress
DNA Methylation Patterns and Association with Graft Injury Severity Post Liver Transplantation.
R. Gehrau, S. Bontha, V. Mas, D. Maluf.
UVA, Charlottesville.
Background: Epigenetics modifications in the graft may influence injury severity and function post liver transplantation (LT). This study aimed to interrogate the effect of different…
2016 American Transplant Congress
Occult Multifocal Hepatocellular Carcinoma in Surgical Patients.
D. Aufhauser Jr,¹ E. Sadot,² D. Murken,¹ K. Eddinger,¹ D. Goldberg,³ E. Furth,⁴ P. Abt,¹ R. DeMatteo,² M. Levine.¹
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Surgery, Memorial Sloan Kettering Cancer Center, New York, NY; ³Medicine, University of Pennsylvania, Philadelphia, PA; ⁴Pathology, University of Pennsylvania, Philadelphia, PA.
Introduction: Resection of hepatocellular carcinoma (HCC) is associated with high rates of intrahepatic recurrence. However, it is unclear whether recurrence results from occult multifocal disease…
2016 American Transplant Congress
Long-Term Outcomes After Splenectomy for Small-for-Size Syndrome in Live Donor Liver Transplantation.
M. Dib, N. Goldaracena, A. Barbas, M. Marquez, G. Sapisochin, C. Beriault, N. Selzner, I. McGilvray, E. Renner, P. Greig, L. Lilly, A. Ghanekar, M. Cattral, M. Selzner, D. Grant.
Transplantation, Toronto General Hospital, Toronto, ON, Canada.
Introduction: The use of lower volume liver grafts has the potential to expand the donor pool in adult-to-adult live donor liver transplantation (LDLT), but is…