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American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2017 American Transplant Congress

    Digital Image Analysis of Pediatric Liver Allograft Biopsies Correlates with METAVIR Fibrosis Score.

    R. Fischer,1 S. Foster,2 J. Daniel,1 R. Hendrickson,1 W. Andrews,1 A. Kats.1

    1Children's Mercy Hospital, Kansas City, MO; 2University of Kansas Medical Center, Kansas City, KS

    Background: Serial surveillance biopsies demonstrate post-transplant inflammation and fibrosis in long-surviving pediatric liver allografts. These changes can ultimately lead to cirrhosis and graft failure. However,…
  • 2017 American Transplant Congress

    Regional Variation in Liver Donor Utilization Across the U.S.

    A. Friedman,1 P. Bagavan,2 S. Florman,3 H. Irving,1 B. Samstein,4 B. Schleich.1

    1LiveOnNY, New York, NY; 2Binghamton University, Binghamton, NY; 3Recanati/Miller Transplant Institute, New York, NY; 4Weill Cornell Medical College, New York, NY

    Unequal patient access to deceased donor liver transplantation across the U.S. has generated efforts to redesign the allocation system. Geographic disparities include the severity of…
  • 2017 American Transplant Congress

    Improved Preservation During Normothermic Ex-Vivo Liver Perfusion with Delta Opioid Agonist (D-Ala2, D-Leu5) Enkephalin (DADLE).

    E. Beal,1 J. Kim,1 D. Hayes Jr.,2 K. Washburn,1 B. Whitson,1 S. Black.1

    1Department of Surgery, Division of Transplant, The Ohio State University Wexner Medical Center, Columbus, OH; 2Departments of Pediatrics and Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH

    Background: The metabolic demand of donor livers during prolonged normothermic ex-vivo perfusion with its associated oxygen stress is a challenge. Delta opioid agonist (D-Ala2, D-Leu5)…
  • 2017 American Transplant Congress

    Effect of Hepatitis C (HCV) Treatment on Rejection Incidence and Severity in Post-Liver Transplant Patients.

    C. Skillin, M. Mba, B. Madani, C. Frenette.

    Organ Transplant, Scripps Clinic, La Jolla, CA

    Introduction: Hepatitis C remains an important source of morbidity and mortality post liver transplant. Little is known about the long term effects of direct acting…
  • 2016 American Transplant Congress

    Use of Autotransfusion During Liver Transplantation for Hepatocellular Carcinoma Does Not Increase Recurrence.

    A. Gupta, M. Ramsay, G. Saracino, T. Anthony, R. Goldstein, G. McKenna, N. Onaca, R. Ruiz, G. Klintmalm, P. Kim.

    Baylor University Medical Center, Dallas, TX.

    IntroductionAutotransfusion (AT) is rarely used in liver transplantation of hepatocellular carcinoma (HCC) patients due to the fear of disease transmission. Leukocyte depleting filters (LDF) can…
  • 2016 American Transplant Congress

    Living Donor Liver Transplantation for Sick Patients with MELD Score ≥ 35.

    R.-S. Soong,1 Y.-C. Wang,1 C.-H. Cheng,1 T.-H. Wu,1 C.-F. Lee,1 T.-J. Wu,1 H.-S. Chou,1 K.-M. Chan,1 C.-S. Lee,2 W.-C. Lee.1

    1Liver and Transplantation Surgery, Chang-Gung Memorial Hospital, Taoyuan, Taiwan; 2Hepatology, Chang-Gung Memorial Hospital, Taoyuan, Taiwan.

    Background: The liver transplant candidates with MELD score ≥ 35 were very sick and with high mortality without liver transplantation. All these patients are in…
  • 2016 American Transplant Congress

    Renal Function Decline Is Higher in the First Year After Liver Transplantation: Final Results from the Italian Observational Study SURF.

    A. Giacomoni,1 M. Cescon,2 G. Magini,3 F. Picciotto,4 U. Cillo,5 M. Senzolo,5 G. Vennarecci,6 P. De Simone.7

    1AO Niguarda, Milano, Italy; 2AO S.Orsola-Malpighi, Bologna, Italy; 3AO Papa Giovanni XXIII, Bergamo, Italy; 4AO Cardarelli, Napoli, Italy; 5AOU di Padova, Padova, Italy; 6O S.Camillo, Roma, Italy; 7AOU Cisanello, Pisa, Italy.

    SURF registry was designed to investigate the evolution of renal function in Italian adult liver transplant (LT) recipients by: exploring the prevalence of chronic kidney…
  • 2016 American Transplant Congress

    Defining Frailty in Liver Transplant Recipients.

    L. Louwers,1 K. Eid,1 J. Plescia,1 N. Presser,1 J. Muntean,1 M. Kattan,2 K. Chagrin,2 C. Miller,1 D. Kelly.1

    1Surgery, Cleveland Clinic, Cleveland, OH; 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.

    PURPOSETo define frailty in the liver transplant (OLT) population to optimize care and assist in predicting post OLT outcomes.METHODSAll adult primary OLT patients from 01/2010…
  • 2016 American Transplant Congress

    Histone Deacetylase-2 Gene Deletion in Mice Mitigates Liver Ischemia/Reperfusion Injury.

    D. Murken,1 D. Aufhauser Jr,1 Z. Wang,2 G. Ge,2 W. Hancock,2,3 M. Levine.1,4

    1Department of Surgery, University of Pennsylvania, Philadelphia, PA; 2Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA; 3Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA; 4Department of Surgery, Children's Hospital of Philadelphia, Philadelphia, PA.

    Introduction: Ischemia/reperfusion injury (IRI) causes significant morbidity in liver transplantation and other surgical scenarios. A better understanding of the molecular mechanisms of IRI is required…
  • 2016 American Transplant Congress

    Incidence of and Risk Assessment for Adverse Cardiovascular Outcomes Following Liver Transplantation: A Systematic Review.

    M. Konerman,1 D. Fritze,2 R. Weinberg,3 E. Spengler,1 C. Sonnenday,2 P. Sharma.1

    1Hepatology, Univ of Michigan, Ann Arbor, MI; 2Transplantation Surgery, Univ of Michigan, Ann Arbor, MI; 3Cardiology, Univ of Michigan, Ann Arbor, MI.

    Purpose: Cardiovascular (CV) events remain a major source of morbidity and mortality following liver transplantation (LT). This review evaluates the incidence of and risk assessment…
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