ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2017 American Transplant Congress

    Identifying Risk of Sepsis Early: A Way to Improve Outcomes for Patients with Early Allograft Dysfunction After Liver Transplantation?

    D. Hoyer, T. Benko, G. Sotiropoulos, A. Paul, F. Saner.

    General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany

    Early Allograft Dysfunction (EAD) after Liver Transplantation (LT) is associated with increased morbidity and mortality, which is strongly associated with sepsis/septic shock. Aim of this…
  • 2017 American Transplant Congress

    Inflammation, Impaired Energy Metabolism and Synthetic Failure Characterize the Liver Transcriptome of End-Stage Idiopathic Pediatric Acute Liver Failure (PALF).

    M. Ningappa,1 P. McKiernan,2 R. Squires,2 Q. Sun,1 B. Higgs,1 K. Soltys,1 G. Bond,1 C. Ashokkumar,1 G. Mazariegos,1 R. Sindhi.1

    1Pediatric Abdominal Surgery, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA

    Background: PALF requiring liver transplantation (LTx) often has no known etiology, and could result from undiagnosed metabolic disorders. Mitochondrial dysfunction is common in PALF, but…
  • 2017 American Transplant Congress

    Disparity in Transplant Referral Patterns Based on Physician Dependent Variables.

    V. Loy, A. Rzepczynski, S. Bello, C. Blackburn, A. Lu.

    Loyola University Medical Center, Maywood, Il

    Introduction: Distance from a liver transplant (LT) center does not affect outcomes; however, rural areas have lower rates of listing and receiving solid organ transplants.…
  • 2017 American Transplant Congress

    Donation After Cardiac Death (DCD) Liver Transplantation (LT) Is Not Associated with Post-LT Renal Dysfunction.

    H. Wadei, M. Mai, D. Lee, K. Croome, B. Rosser, A. Keaveny, B. Taner.

    Transplant, Mayo Clinic, Jacksonville, FL

    The relationship between DCD LT and post-LT renal dysfunction is unclear. Aim: Determine the effects of DCD LT compared to donation after brain death (DBD)…
  • 2017 American Transplant Congress

    Simultaneous Liver-Kidney Transplants Using Donation After Cardiac Death Donors Long Term Outcomes Not Inferior to Brain Dead Donors.

    J. Alvarez-Casas, S. Sultan, J. Scalea, K. McClure, J. LaMattina, D. Bruno, S. Hanish, R. Barth.

    University of Maryland School of Medicine, Baltimore, MD

    Background:The Simultaneous use of both Liver and Kidney from the same DCD donor has become controversial with some authors advocating that DCD organs should not…
  • 2017 American Transplant Congress

    Liver Transplantation Outcomes Using Anti-Thymocyte Globulin Induction in Patients with Autoimmune Hepatitis.

    S. LeCorchick, A. Sharma, I. Yakubu, C. Bhati, T. Reichman, L. Kang, M. Levy.

    Transplantation Surgery, Virginia Commonwealth University, Richmond, VA

    Background: The use of rabbit anti-thymocyte globulin (ATG) induction in high immunological risk patients with autoimmune hepatitis (AIH) could lower the rejection rates after liver…
  • 2017 American Transplant Congress

    Personalizing Immunosuppression with Molecular Phenotyping in Pediatric Liver Transplantation.

    M. Ningappa, C. Ashokkumar, Q. Sun, B. Higgs, K. Soltys, G. Bond, G. Mazariegos, R. Sindhi.

    Pediatric Abdominal Transplant, Children's Hospital of Pittsburgh of UPMC, Pittsburgh

    Background: Optimizing immunosuppression requires selecting an agent which can inhibit the dominant anti-rejection mechanism in individual children with liver transplantation (LTx). Extended use of steroids,…
  • 2017 American Transplant Congress

    Induction of Mixed Chimerism to Prolong Liver Allograft Survival in Cynomolgus Monkeys.

    E. Berglund, J. Stern, P. Alonso Guallart, S. Chaudhry, S. Kofman, M. Danton, J. Weiner, J. Lefkowitch, S. Baker, M. Martinez, Y. Kato, T. Kato, M. Sykes, A. Griesemer.

    CCTI, Columbia University, New York, NY

    Purpose: Spontaneous liver tolerance occurs in highly selected patients with stable liver function. There is an unmet need for a safe and reliable regimen allowing…
  • 2017 American Transplant Congress

    Effect of Academic Detailing with Prescribers as an Antimicrobial Stewardship Intervention in Solid Organ Transplant Patients.

    M. So,1 A. Morris,1,2 C. Bell,2 A. Humar,1 S. Husain.1

    1University Health Network, Toronto, ON, Canada; 2Sinai Health System, Toronto, ON, Canada

    IntroductionThe role of academic detailing (AD) as an antimicrobial stewardship intervention, where the steward meets the prescribers in their practice setting to provide personal educational…
  • 2017 American Transplant Congress

    Prolonged Survival with Co-Stimulatory Blockade Based Immunosuppression in Pig-to-Primate Liver Xenotransplantation.

    J. Shah, M. Patel, N. Elias, I. Rosales, N. Navarro-Alvarez, M. Hertl, A. Cosimi, R. Colvin, J. Markmann, D. Sachs, P. Vagefi.

    Massachusetts General Hospital, Boston, MA

    Background: Since the first attempt in 1968, survival following pig-to-baboon liver xenotransplantation (LXT) has been limited to <9-days due to a lethal coagulopathy. To improve…
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