2017 American Transplant Congress
Effect of Epigenetic Modifications in Ischemia-Reperfusion-Injury Post Liver Transplantation: An Integrative Approach.
Surgery, UVA, Charlottesville; VCU, Richmond
Background Free radicals generated during ischemia reperfusion injury (IRI) might result in epigenetic modifications and gene expression (GE) changes affecting graft outcomes. Integrative analyses of…2017 American Transplant Congress
Optimizing Survival Outcomes for Advanced Age Patients Undergoing Liver Transplant.
Houston Methodist Hospital, Houston, TX
ObjectivesAge at liver transplant (LT) is progressively increasing and is a known risk factor for mortality. We sought to evaluate preTx predictors for mortality among…2017 American Transplant Congress
Safety of Liver Donation from Living Donors with Sickle Cell Trait.
Background:Living donor liver transplant (LDLT) is an important source of organs particularly with the cadaveric organ shortage. It is the main source of liver transplant…2017 American Transplant Congress
Acute Renal Replacement Therapy in Pediatric Liver Transplantation: A Predictor of Increased Risk.
1Surgery, UCLA, Los Angeles, CA; 2Pediatric Gastroenterology, UCLA, Los Angeles, CA
BackgroundAmong pediatric patients (≤18 yrs) awaiting liver transplantation (LT), limited data exist on the prognostic significance of acute (<90d) renal replacement therapy (RRT) prior to…2017 American Transplant Congress
The Beneficial Effects of mTOR Inhibitors on Liver Resident Natural Killer Cells.
Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan
(Background) The immunosuppressive regimen currently used after organ transplantation reduces adaptive components. Therefore, the innate immune cells play pivotal roles in immune surveillance and defense…2017 American Transplant Congress
Liver Transplantation Tolerance Using Outbred Mice.
Success of organ transplantation currently depends on life-time immunosuppression, resulting in severe side effects. Induction of donor specific tolerance is ideal, which actually spontaneously occurs…2017 American Transplant Congress
Delayed Calcineurin Inhibitor Introduction and Long Term Renal Outcomes in Liver Transplant Recipients Receiving Basiliximab Induction.
BACKGROUND Basiliximab may be used to delay the initation of calcineurin inhibitors (CNI) in patients with renal injury after liver transplantation (LT). The optimal time…2017 American Transplant Congress
Liver Allograft Hepatitis and Graft Loss After Hepatitis C Clearance.
Surgery, University of Maryland School of Medicine, Baltimore, MD
Successful HCV therapies should improve inferior outcomes of liver transplantation (LT) for HCV cirrhosis. We hypothesize certain patients may be predisposed to heterologous immunity that…2017 American Transplant Congress
Increased Use of Donation After Cardiac Death Donors Increases Access to Transplantation without Adverse Effect on Outcomes.
UT/Methodist University Hospital, Memphis, TN
IntroductionAs the transplant community discusses redistricting to address potential imbalance in loco-regional liver distribution, liver transplant programs will need to identify strategies to maximize access…2017 American Transplant Congress
Ischemia-Reperfusion Injury-Induced Innate Immune Signaling in Human Orthotopic Liver Transplantation.
Background: Ischemia-reperfusion injury (IRI) is a major risk factor in the development of acute and chronic graft rejection in orthotopic liver transplantation (OLT); however, no…
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