Articles tagged "Liver transplantation"

2017 American Transplant Congress
Delayed Calcineurin Inhibitor Introduction and Long Term Renal Outcomes in Liver Transplant Recipients Receiving Basiliximab Induction.
N. Lange,^1,2 D. Salerno,¹ C. Sammons.²
¹Department of Pharmacy, Weill Cornell Medical Center, New York, NY; ²Department of Pharmacy, Columbia University Irving Medical Center, New York, NY
BACKGROUND Basiliximab may be used to delay the initation of calcineurin inhibitors (CNI) in patients with renal injury after liver transplantation (LT). The optimal time…
2017 American Transplant Congress
Liver Allograft Hepatitis and Graft Loss After Hepatitis C Clearance.
D. Bruno, S. Brown, S. Hanish, J. LaMattina, W. Hutson, S. Kottilil, W. Twadell, R. Barth.
Surgery, University of Maryland School of Medicine, Baltimore, MD
Successful HCV therapies should improve inferior outcomes of liver transplantation (LT) for HCV cirrhosis. We hypothesize certain patients may be predisposed to heterologous immunity that…
2017 American Transplant Congress
Kidney Quality Dramatically Influences Patient and Death Censored Graft Survival in SLK Recipients.
T. Zens, J. Danobeitia, P. Stahler, G. Leverson, R. Redfield, A. D'Alessandro, L. Fernandez.
Department of Transplant Surgery, University of Wisconsin, Madison, WI
Introduction: Renal grafts used in simultaneous kidney liver (SLK) transplants are allocated on “center based” arbitrary clinical criteria without entering the kidney allocation algorithm. The…
2017 American Transplant Congress
Early Acute Cellular Rejection(eACR) as a Marker of Immunologic Competency Following Liver Transplantation(LT).
V. Kirchner, A. Bandgdiwala, D. Vock, M. Hassan, R. Kandaswamy, J. Lake, N. Lim, A. Mahgoub, E. Minja, A. Pugalenthi, B. Sengupta, O. Serrano, J. Thompson, W. Payne, T. Pruett, S. Chinnakotla.
University of Minnesota, Minneapolis, MN
Background:Historically eACR did not adversely impact patient survival(PS). Since infection(Ifx) is major cause of death(COD) among LT recipients, we hypothesized that eACR is marker of…
2017 American Transplant Congress
Prominence of Graft-Infiltrating PD-L1^hi Cross-Dressed Dendritic Cells in Mouse Liver Transplant Tolerance.
Y. Ono, A. Perez Gutierrez, S. Yokota, O. Yoshida, T. Nakao, G. Camirand, D. Geller, A. Thomson.
Surgery, University of Pittsburgh, Pittsburgh, PA
Background: The mechanism underlying spontaneous liver allograft tolerance remains unclear. Given recent reports on the key role of recipient mouse dendritic cells (DCs) in host…
2017 American Transplant Congress
Glucocorticoid Receptor – Relaxin Signaling in Liver Transplant Ischemia-Reperfusion Injury (IRI): From Bench-to-Bedside.
S. Kageyama,¹ K. Nakamura,¹ R. Sossa,² E. Reed,² N. Datta,¹ A. Zarrinpar,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹The Dumont-UCLA Transplant Center, Department of Surgery, David Geffen School of Medicine at University of California, Los Angeles, CA; ²Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA
Background: Glucocorticoid receptor (GR) serves as a receptor for relaxin (RLX), a pregnancy hormone, with novel vasoactive and tissue remodeling properties. A phase III clinical…
2017 American Transplant Congress
Predicting Recurrence Prior to Transplant: The Response of HCC to Chemoembolization.
T. Sandow,¹ H. Bohorquez,² D. Kirsch,¹ P. Thevenot,³ K. Nunez,³ A. Albar,¹ D. DeVun,¹ J. Gimenez,¹ G. Galliano,⁴ A. Cohen,² G. Loss,² D. Kay,¹ P. Gulotta.¹
¹Radiology, Ochsner Clinic Foundation, New Orleans, LA; ²Transplant Surgery, Ochsner Clinic Foundation, New Orleans, LA; ³Institute of Translational Research, Ochsner Clinic Foundation, New Orleans, LA; ⁴Pathology, Ochsner Clinic Foundation, New Orleans, LA
Purpose:This study assesses imaging response characteristics of patients with hepatocellular carcinoma (HCC) to chemoembolization (TACE) as a bridge to transplant and the risk of post-transplant…
2017 American Transplant Congress
Effect of Epigenetic Modifications in Ischemia-Reperfusion-Injury Post Liver Transplantation: An Integrative Approach.
D. Bagchi, S. Bontha, M. Dozmorov, A. Fernandez, V. Mas, D. Maluf.
Surgery, UVA, Charlottesville; VCU, Richmond
Background Free radicals generated during ischemia reperfusion injury (IRI) might result in epigenetic modifications and gene expression (GE) changes affecting graft outcomes. Integrative analyses of…
2017 American Transplant Congress
Readmissions After Liver Transplantation–They May Be Predictable, but Are They Inevitable?
B. O'Brien, C. Mardis, A. Mardis, J. Fleming, H. Meadows, N. Patel, N. Pilch, C. Perez, M. Sell, A. Rogers, I. Lee, J. McGillicuddy, K. Chavin, D. DuBay, D. Taber.
Dept of Tx Surgery, Tx ICCE, Dept of Pharmacy, MUSC, Charleston, SC
Purpose: Published studies suggest that approximately 40% of OLTx recipients are readmitted within 30 days. The aim of this study is to analyze the risk…
2017 American Transplant Congress
Incidence and Outcomes of Re-Explorations in Living Donor Liver Transplantation.
V. Varma, S. Sable, S. Kapoor, A. Chauhan, V. Kumaran.
Hepato-Biliary-Pancreatic Surgery and Liver Transplantation, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, Maharashtra, India
Introduction: Re-exploration in Living Donor Liver Transplantation(LDLT) is required in patients for various causes, bleeding being the commonest cause. The outcome of these patients is…