Articles tagged "Liver transplantation"

2017 American Transplant Congress
Normothermic Regional Perfusion of Donors Following Circulatory Death Improves Outcomes in Liver Transplantation.
E. Mowlem,¹ L. Randle,² C. Fear,¹ K. Crick,¹ S. Messer,⁴ S. Large,⁴ A. Butler,³ C. Watson.³
¹Cambridge Transplant Unit, Addenbrookes Hospital, Cambridge, United Kingdom; ²OrganOx Ltd, Oxford, United Kingdom; ³Dept of Surgery, University of Cambridge, Cambridge, United Kingdom; ⁴Papworth Hospital, Cambridge, United Kingdom
Introduction: Donation after Circulatory Death (DCD) provides 23% of UK livers for transplantation, but such transplants are associated with more primary graft function and early…
2017 American Transplant Congress
Clinical Evaluation of the Safety and Preliminary Efficacy of Continuous Infusion of Treprostinil to Prevent Ischemia and Reperfusion Injury in Adult Orthotopic Liver Transplant Recipients.
O. Almazroo,¹ M. Miah,¹ V. Pillai,¹ A. Humar,² A. Tevar,² C. Hughes,² A. AlKhafaji,³ A. Demetris,⁴ S. Dermont,² S. Fedorek,² H. Johnson,¹ R. Lopez,² R. Planinsic,² B. Sengupta,² I. Sethu,² M. Sturdevant,² S. Ziobert,¹ R. Venkataramanan.^1,2,4
¹Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA; ²Thomas Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; ³Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA; ⁴Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA
Introduction:Liver transplantation is currently the only therapeutic option for patients with end stage liver diseases. Liver allografts undergo cold ischemic injury and warm reperfusion injury…
2017 American Transplant Congress
Community Health, Center Proximity, and Liver Transplant Waitlist Mortality.
R. Lynch,¹ K. Ross,¹ D. Goldberg,² R. Patzer.¹
¹Surgery, Emory University, Atlanta, GA; ²Medicine, University of Pennsylvania, Philadelphia, PA
Background: While regional organ availability is frequently discussed in allocation policy, the impact of community-level factors and access to a transplant center on waitlist mortality…
2017 American Transplant Congress
The Combined Effects of Induction Regimens and Antiviral Prophylaxis on the Risk of CMV Infection in Different Serostatus Subgroups After Liver Transplantation.
C. Low,² S. Hosseini-Moghaddam,^1,2 C. Rotstein,² E. Renner,² A. Humar,² D. Kumar,² S. Husain.²
¹Medicine, Western University, London Health Sciences Centre, London, Canada; ²University Health Network, Toronto, Canada
Introduction: Simultaneous effects of anti-CMV prophylaxis and induction regimens on cytomegalovirus (CMV) infection after liver transplantation (LTRs) have not been studied. We determined the magnitude…
2017 American Transplant Congress
Re-Evaluation of Imaging Studies in Patients with Hepatocellular Carcinoma at a Transplant Center Impacts Patient Care.
A. Kardashian, B. Madani, C. Frenette.
Organ Transplant, Scripps Clinic, La Jolla, CA
Introduction: The United Network for Organ Sharing (UNOS) requires confirmation of HCC based on imaging to be made at a transplant center. This places a…
2017 American Transplant Congress
The Use of an Haemoglobin Based Oxygen Carrier in a Human Liver Model of Normothermic Machine Perfusion.
Y. Boteon,¹ R. Laing,¹ R. Bogal,¹ D. Neil,² A. Smith,² B. Stephenson,² A. Schlegel,² S. Hübscher,² D. Mirza,² S. Afford,¹ H. Mergental.²
¹Center of Liver Research, University of Birmingham, Birmingham, United Kingdom; ²Liver Unit Queen Elizabeth Hospital, University Hospital Birmingham, Birmingham, United Kingdom
Normothermic machine perfusion of the liver (NMP-L) is a novel technique that preserves liver grafts in an environment that mimics physiological conditions and therefore enables…
2017 American Transplant Congress
Tenofovir Use Is Not Associated with Reduced Bone Density or Fractures in Liver Transplant Recipients.
N. Lim, C. Engler, J. Lake.
University of Minnesota, Minneapolis, MN
BackgroundTenofovir disproxil fumarate (TDF) and reduced bone density in the HIV population is well-documented. The effect of TDF use on bone density in patients who…
2017 American Transplant Congress
Patency of Autologous Portal Vein “Y“ Graft in Anterior Sector Outflow Reconstruction in Adult Living Donor Right Lobe Grafts.
S. Kapoor, B. Nath, V. Varma, S. Sable, A. Chauhan, V. Kumaran.
Liver Transplantation & HPB Surgery, Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute, Mumbai, Maharashtra, India
Anetrior sector outflow reconstruction is followed by most centers performing right lobe liver transplantation. Recanalised umbilical vein, cryopreserved cadaveric veins/ arteries, PTFE and Recipient's portal…
2017 American Transplant Congress
Comparing Outcomes Between Technical Variant Liver Allografts and Whole Allografts in Pediatric Liver Transplantation: A Single Center's Experience.
A. Gallo,¹ J. Lee,¹ M. Damian,² D. Stoltz,¹ C. Bonham,¹ C. Esquivel,¹ J. Mendoza.³
¹Surgery, Stanford University, Palo Alto, CA; ²Intensive Care, Stanford University, Palo Alto, CA; ³Anesthesia, Stanford University, Palo Alto, CA
Objective: To compare the outcome of technical variant liver transplants to whole allograft liver transplants in pediatric recipients.Methods: A single center retrospective analysis of outcomes…
2017 American Transplant Congress
Malignancy in Patients Undergoing Simultaneous Heart-Liver and Heart-Kidney Transplant.
A. Chin, A. Habertheuer, A. Chou, M. Acker, M. Williams, P. Atluri, C. Bermudez, P. Vallabhajosyula.
University of Pennsylvania, Philadelphia, PA
Purpose: While evidence suggests that patients undergoing simultaneous heart-liver and heart-kidney transplant may have improved immunoprotection from allograft rejection versus patients undergoing heart transplant only,…