ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2017 American Transplant Congress

    Efficacy and Safety of Everolimus with Reduced Tacrolimus or Cyclosporine in Pediatric Liver Transplant Recipients: 12-Month Results from H2305 Study.

    A. Weymann,1 R. Ganschow,1 B. Ericzon,1 A. Dhawan,1 K. Sharif,1 E.-D. Martzloff,2 B. Rauer,2 J. Ng,2 P. Lopez.2

    1H2305 Study Group, St Louis; 2Novartis Pharma AG, Basel, Switzerland

    Purpose: Everolimus (EVR) facilitated calcineurin inhibitor (CNI) reduction has shown improved renal function (RF) without compromising efficacy in adult liver transplant recipients (LTxR). Here we…
  • 2017 American Transplant Congress

    Contemporary Outcomes and Risk Factors of Acute Graft-versus-Host Disease After Liver Transplant.

    J. Markus, A. Bukannan, B. Kashat, R. Salgia.

    Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI

    Introduction:Acute graft-versus-host-disease (GVHD) is a rare complication of orthotopic liver transplant (LT) that has an estimated incidence of 0.1%-2% per year. This complication of OLT…
  • 2017 American Transplant Congress

    Live Donor Liver Transplantation Using Grafts with More Than Two Bile Ducts – Does It Affect Patient Outcome?

    D. Kollmann, G. Sapisochin, N. Selzner, M. Cattral, P. Greig, L. Lilly, I. McGilvray, A. Ganekar, D. Grant, M. Selzner, N. Goldaracena.

    Multi Organ Transplant Program, Department of Surgery, Toronto General Hospital, Toronto, ON, Canada

    Introduction: It's been described that the use of live donor (LD) liver grafts with multiple bile ducts (BD) increases the risk of BD related complications…
  • 2017 American Transplant Congress

    B Cells in Liver Transplant Tolerance.

    M. Morita,1 G. Asonye,1 N. Gupta,1 J. Fung,2 C. Miller,3 S. Qian,1,3 L. Lu.1,3

    1Immunology, Cleveland Clinic, Cleveland; 2University of Chicago, Chicago, MI; 3General Surgery, Cleveland Clinic, Cleveland, OH

    In mice liver transplantation, the liver allografts can be accepted across fully mismatched MHC without immunosuppression. After transplantation, T cells infiltrate into the graft in…
  • 2017 American Transplant Congress

    A New Strategy for Loco-Regional Therapy of Hepatocellular Carcinoma: Stereotactic Body Radiotherapy as a Bridge to Liver Transplantation.

    T. Uemura,1 A. Kirichenko,2 M. Bunker,3 M. Vincent,1 L. Machado,1 A. Singhal,1 N. Thai.1

    1Transplant Surgery, Allegheny General Hospital, Pittsburgh; 2Radiation Oncology, Allegheny General Hospital, Pittsburgh; 3Pathology, Allegheny General Hospital, Pittsburgh

    Background: Transarterial chemoembolization (TACE) or radiofrequency ablation are often used as local Hepatocellular Carcinoma (HCC) treatment while waiting for a liver transplant (LTx). However, it…
  • 2017 American Transplant Congress

    Direct Intrahepatic Delivery of Pegylated-Catalase Is Protective in a Rat Ischemia-Reperfusion Injury Model.

    E. Beal,1 S. Black,1 J. Kim,1 V. Velazquez,2 K. Washburn,1 D. Hayes Jr.,3 B. Whitson.1

    1Department of Surgery, Division of Transplant, The Ohio State University Wexner Medical Center, Columbus, OH; 2Center for Vaccines and Immunity, The Research Institute at Nationwide Childrens Hospital, Columbus, OH; 3Departments of Pediatrics and Internal Medicine, The Ohio State University College of Medicine, Columbus, OH

    Introduction: Ischemia-reperfusion injury (IRI) is characterized by cessation of blood flow to an organ or tissue leading to accumulation of toxic metabolites and free radicals,…
  • 2017 American Transplant Congress

    EPOR2/ßcR2-Independendent Effects of Low-Dose Epoetin-a in Porcine Liver Transplantation.

    L. Kebschull,1 F. Becker,1 L. Theilmann,1 B. Heitzplatz,2 W. Uennigmann,1 H. Spiegel,1 D. Palmes.1

    1Department for General and Visceral Surgery, University Hospital Münster, Münster, Germany; 2Pathology, University Hospital Münster, Münster, Germany

    Introduction: Ischemia-reperfusion injury (IRI) remains the key component of graft damage during transplantation. Mechanistically, cold-induced apoptosis, microcirculatory disturbances and radical oxygen species formation contribute to…
  • 2017 American Transplant Congress

    Diabetes in Liver Transplantation: Evaluation of Management and Associated Clinical Outcomes.

    A. Rogers,2 N. Patel,2 H. Meadows,2 A. Mardis,2 J. Fleming,2 C. Perez,2 I. Lee,2 M. Sell,2 B. O'Brien,2 D. Taber,1 K. Chavin,1 D. Dubay,1 C. Mardis,2 N. Pilch.1

    1Department of Surgry Division of Transplant, Medical University of South Carolina, Charleston, SC; 2Department of Pharmacy, Medical University of South Carolina, Charleston, SC

    PurposeThere is limited data with diabetes management in liver transplant recipients and associated outcomes, this study aims to evaluate the long-term diabetes management in this…
  • 2017 American Transplant Congress

    MMR and Varicella Immunity After Pediatric Liver Transplant.

    A. Waugh,1 A. Opekun,1,2 F. Munoz,2 T. Miloh.2

    1Baylor College of Medicine, Houston; 2Texas Children's Hospital, Houston

    Background: Children listed for liver transplantation (LT) are at risk for decreased vaccine response due to age, underlying disease, or waning immunity. Live attenuated vaccines…
  • 2017 American Transplant Congress

    Differences in Racial and Sex Disparities in Liver Transplantation Outcomes Between Older and Younger Adult Recipients.

    Q. Huang, C. Haugen, X. Luo, A. Massie, M. McAdams-DeMarco, D. Segev.

    Johns Hopkins University, Baltimore

    Background: More older adults underwent liver transplantation (LT) in the past decade. While racial and sex disparities in LT outcomes have been reported in general,…
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