Articles tagged "Liver transplantation"

2017 American Transplant Congress
Expanded Criteria for HCC in Liver Transplantation.
M. Haberal,¹ A. Akdur,¹ G. Moray,¹ G. Arslan,² F. Ozcay,³ H. Selcuk,⁴ H. Ozdemir.⁵
¹General Surgery and Transplantation, Baskent University, Ankara, Turkey; ²Anesthesiology, Baskent University, Ankara, Turkey; ³Pediatric Gastroenterology, Baskent University, Ankara, Turkey; ⁴Gastroenterology, Baskent University, Ankara, Turkey; ⁵Pathology, Baskent University, Ankara, Turkey
Introduction: Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and the third highest cause of death related to malignancy. Since HCC diagnosis is…
2017 American Transplant Congress
Evaluation of Vancomycin Resistant Enterococcus (VRE) Colonization and Infection Rate in Adult Liver Transplant Patients.
E. Aldag,¹ G. Fouth,¹ R. Pedersen,¹ L. Fehrenbacher,^1,2 A. Sahajpal,¹ V. Gunabushanam,¹ D. Kramer.¹
¹Aurora St Luke's Medical Center, Milwaukee; ²Concordia University Wisconsin School of Pharmacy, Mequon
Background: VRE infections are associated with higher morbidity and mortality among patients undergoing liver transplantation.Objective: The primary outcomes are to look at VRE infection rate…
2017 American Transplant Congress
Effective Thrombolytic Therapy of Hepatic Artery Thrombosis After Liver Transplantation – A Single-Center Experience.
M. Chen,¹ X. Lin,² W. Ju,¹ D. Wang,¹ Y. Ma,¹ L. Wu,¹ X. He,¹ G. Chen.¹
¹Organ Transplant Center, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China; ²Department of Thyroid and Breast Surgery, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China
BACKGROUND: Hepatic artery thrombosis (HAT) is a common complication of liver transplantation which causes lots of graft loss. The anastomoses of hepatic artery requires delicate…
2017 American Transplant Congress
Long-Term Analysis of Combined Liver-Lung Transplant Outcomes at a Single-Center.
K. Freischlag,¹ B. Ezekian,² M. Mulvihill,² S. Knechtle.²
¹School of Medicine, Duke University, Durham, NC; ²Surgery, Duke University, Durham, NC
Purpose: Combined liver-lung transplantation (CLLT) is indicated in patients who would not be expected to survive transplantation of either organ alone. We present one of…
2017 American Transplant Congress
Digital Image Analysis of Pediatric Liver Allograft Biopsies Correlates with METAVIR Fibrosis Score.
R. Fischer,¹ S. Foster,² J. Daniel,¹ R. Hendrickson,¹ W. Andrews,¹ A. Kats.¹
¹Children's Mercy Hospital, Kansas City, MO; ²University of Kansas Medical Center, Kansas City, KS
Background: Serial surveillance biopsies demonstrate post-transplant inflammation and fibrosis in long-surviving pediatric liver allografts. These changes can ultimately lead to cirrhosis and graft failure. However,…
2017 American Transplant Congress
Regional Variation in Liver Donor Utilization Across the U.S.
A. Friedman,¹ P. Bagavan,² S. Florman,³ H. Irving,¹ B. Samstein,⁴ B. Schleich.¹
¹LiveOnNY, New York, NY; ²Binghamton University, Binghamton, NY; ³Recanati/Miller Transplant Institute, New York, NY; ⁴Weill Cornell Medical College, New York, NY
Unequal patient access to deceased donor liver transplantation across the U.S. has generated efforts to redesign the allocation system. Geographic disparities include the severity of…
2017 American Transplant Congress
Improved Preservation During Normothermic Ex-Vivo Liver Perfusion with Delta Opioid Agonist (D-Ala2, D-Leu5) Enkephalin (DADLE).
E. Beal,¹ J. Kim,¹ D. Hayes Jr.,² K. Washburn,¹ B. Whitson,¹ S. Black.¹
¹Department of Surgery, Division of Transplant, The Ohio State University Wexner Medical Center, Columbus, OH; ²Departments of Pediatrics and Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH
Background: The metabolic demand of donor livers during prolonged normothermic ex-vivo perfusion with its associated oxygen stress is a challenge. Delta opioid agonist (D-Ala2, D-Leu5)…
2017 American Transplant Congress
Effect of Hepatitis C (HCV) Treatment on Rejection Incidence and Severity in Post-Liver Transplant Patients.
C. Skillin, M. Mba, B. Madani, C. Frenette.
Organ Transplant, Scripps Clinic, La Jolla, CA
Introduction: Hepatitis C remains an important source of morbidity and mortality post liver transplant. Little is known about the long term effects of direct acting…
2017 American Transplant Congress
Sirolimus Prolonged Survival After Living Donor Liver Transplantation for HCC Beynd Milan Criteria; Outcome of a Multicenter Prospective Randomized Phase II Trial (ClinicalTrials.gov Identifier: NCT01374750).
K.-W. Lee,¹ S.-H. Kim,² N.-J. Yi,¹ S.-K. Hong,¹ G. Yoon,¹ H. Kim,¹ D. Oh,¹ S.-S. Han,² S.-J. Park,² K.-S. Suh.¹
¹Department of Surgery, Seoul National University, Seoul, Republic of Korea; ²Center for Liver Cancer, National Cancer Center, Goyangsi, Republic of Korea
Background:It is unclear whether the reported benefit of mTORi in LT for HCC is from direct effect of mTOR inhibitors. We aimed to compare directly…
2017 American Transplant Congress
TIM-3 – CEACAM1 Checkpoint Regulation of T-Cell Activation and Hepatocellular Function in Liver Transplantation.
K. Nakamura,¹ S. Kageyama,¹ M. Kujawski,³ R. Sosa,² E. Reed,² A. Zarrinpar,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Dept. Surgery, UCLA, Los Angeles, CA; ²Dept. Pathology, UCLA, Los Angeles, CA; ³Dept. Molecular Immunology, City of Hope, Duarte, CA
Background/Aim: We have documented crucial role of TIM-3 dependent T cell dysfunction in mouse orthotopic liver transplantation (OLT). CEACAM1 (CD66a; CM1; Carcinoembryonic Antigen-Related Cell Adhesion…