ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2017 American Transplant Congress

    Long-Term Pediatric Live-Donor Liver Transplantation Survivors: Patient and Allograft Outcomes.

    N. Celik,1 A. Ganoza,1 G. Bond,1 K. Soltys,1 R. Sindhi,1 P. McKiernan,3 A. Humar,2 G. Mazariegos.1

    1Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Thomas E. Starzl Transplantation Institute, Pittsburgh, PA; 3Division of Pediatric Gastroenterology, Pittsburgh, PA

    Aim: To determine the patient and allograft outcomes at 5 years after pediatric live-donor liver transplantation (LDLT).Methods: Children with a minimum of 5-year survival post-transplantation…
  • 2017 American Transplant Congress

    Sequential Liver-Kidney Transplantation Is Equivalent to Simultaneous Liver–Kidney Transplantation in Candidates Requiring Dialysis Pre-Transplant.

    M. Mulvihill, B. Yerokun, R. Davis, K. Anderson, M. Hartwig, A. Barbas.

    Surgery, Duke University Medical Center, Durham, NC

    Introduction: Liver transplant is the optimal therapy for patients with end-stage liver disease (ESLD). Appropriately-selected candidates with renal impairment benefit from transplantation of liver and…
  • 2017 American Transplant Congress

    Experimental Study of Hepatocyte Proliferation Regulated by miR26a.

    J. Zhou, X. Yuan, W. Ju, X. Jiao, D. Wang, X. Zhu, X. He.

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    Objective To investigate mechanisms of regulation on hepatocyte proliferation by miRNAs. Methods Normal hepatocyte in ivtro was transfected with vectors harboring Ad5/anti-miR26a or Ad5/miR26a, and…
  • 2017 American Transplant Congress

    National Variation in Liver Transplant Immunosuppression in the U.S..

    M. Nazzal,1 R. Ouseph,1 M. Schnitzler,1 Z. Zhang,1 D. Axelrod,2 D. Segev,3 A. Naik,4 H. Randall,1 D. Brennan,5 B. Kasiske,6 G. Hess,7 T. Alhamad,5 K. Lentine.1

    1St Louis Univ, St Louis; 2E Carolina Univ, Greenville; 3Johns Hopkins, Baltimore; 4U Michigan, Ann Arbor; 5Washington Univ, St Louis; 6SRTR, Minneapolis; 7Symphony Health, Philadelphia

    Variation in immunosuppression (ISx) for liver transplant (LTx) across US programs has not been described. We examined a novel database integrating national registry and pharmacy…
  • 2017 American Transplant Congress

    Tangible Benefits in Caregiving Burden Among Spouses/Partners of Transplant Patients: Adding “Donor Benefit” to Live Donor Risk Assessment.

    S. Rasmussen, L. Duquette, M. Henderson, D. Segev.

    JHU, Baltimore

    Background The mental and physical health of spouses and co-habiting partners (dyads) are highly correlated. Dialysis entails significant caregiving burden and decreases the quality of…
  • 2017 American Transplant Congress

    Use of Ledipasvir/Sofosbuvir with or without Ribavirin in Patients Post-Liver Transplant: Evaluation of Real-World Datasets.

    S. Flamm,1 M. Charlton,2 M. Manns,3 M. Prieto,4 I. Fernandez,5 M. Londono,6 R. Kwok,7 C. Smith,8 S. Lee,9 H. Ngo,9 A. Osinusi,9 A. Copans,9 L. Rossaro,9 M. Shoreibah,10 O. Massoud,10 M. Curry,11 M. Bourliere.12

    1Northwestern University, Chicago; 2Intermountain Medical Center, Murray; 3Hannover Medical School, Hannover, Germany; 4Hospital Universitari I Politecnic La Fe, Valencia, Spain; 5Hospital Universitario 12 de Octubre, Madrid, Spain; 6Servicio de Hepatología. Hospital Clinic, Barcelona, Spain; 7Walter Reed National Military Medical Center, DC; 8Medstar Georgetown University Hospital, Georgetown; 9Gilead Sciences, Inc., Foster City; 10University of Alabama Birmingham, Birmingham; 11Beth Israel Deaconess Medical Center, Boston; 12Hospital Saint Joseph, Marsielle, France

    PURPOSE: Post-liver transplant(LT) patients with HCV are considered a difficult-to-treat population. Ledipasvir/sofosbuvir(LDV/SOF) +ribavirin(RBV) for 12 weeks is approved in GT1 LT recipients based on the…
  • 2017 American Transplant Congress

    First Report of Human Liver Transplantation After Normothermic Machine Perfusion (NMP) in the United States.

    Q. Liu, B. Soliman, G. Iuppa, A. Nassar, A. Hassan, T. Diago Uso, K. Hashimoto, F. Aucejo, M. Fujiki, B. Eghtesad, J. Cywinski, S. Irefin, J. Fung, K. Abu-Elmagd, C. Miller, C. Quintini.

    Cleveland Clinic, Cleveland

    NMP is a novel preservation method for liver grafts. We transplanted 10 human livers after NMP to test the safety and feasibility of NMP on…
  • 2017 American Transplant Congress

    Renal Function After Liver Transplantation Alone in Patients Meeting the Proposed UNOS Simultaneous Liver-Kidney (SLK) Criteria.

    K. Roayaie,1 E. Langewisch,2 J. Burg,1 C. Enestvedt,1 E. Maynard,1 D. Scott.1

    1Surgery, Oregon Health & Science University, Portland, OR; 2Medicine, University of Nebraska Medical Center, Omaha, NE

    Background & Aim: The United Network for Organ Sharing (UNOS) has proposed criteria for simultaneous liver and kidney transplantation (SLK) incorporating strict definitions for eligibility…
  • 2017 American Transplant Congress

    Tissue Transcriptional Profile of Portal Inflammation with Interface Activity in Pediatric Liver Transplant (LT) Recipients with Normal Liver Tests Closely Resembles T Cell Mediated Rejection (TCMR).

    A. Sanchez-Fueyo, S. Feng, A. Demetris, J. Bucuvalas, J. Lozano, J. Magee, K. Spain, S. Kanaparthi, iWITH Investigators.

    KCL, London, United Kingdom; UCSF, SF; Pittsburgh, Pittsburgh; Cincinnati, Cincinnati; CiberEHD, Barcelona, Spain; Michigan, Ann Arbor; Rho, Chapel Hill; ITN, Bethesda; NIDDK/NIAID/NIH, Bethesda

    Background: Significant inflammation±fibrosis is frequently seen in biopsies (bxs) of pediatric LT recipients with normal liver tests assessed for immunosuppression withdrawal. The pathogenesis of these…
  • 2017 American Transplant Congress

    Comparison of Long-Term Survival Outcome Between Primary Liver Transplantation and Hepatic Resection with Consequent Salvage Transplantation for Hepatocellular Carcinoma within Milan Criteria – A Single-Center Experience.

    K. Ng,1 K. Chok,1 A. Chan,1 T. Wong,1 J. Fung,2 C.-M. Lo.1

    1Department of Surgery, The University of Hong Kong, Hong Kong, Hong Kong; 2Department of Medicine, The University of Hong Kong, Hong Kong, Hong Kong

    Background: Whether primary liver transplantation (PLT) is superior to the upfront hepatic resection (HR) and salvage liver transplantation (SLT) for hepatocellular carcinoma (HCC) within Milan…
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