Articles tagged "Liver transplantation"

2018 American Transplant Congress
Ethnic and Age Disparities in Outcomes among Liver Transplant Waitlist Candidates
M. Mustian,¹ S. Gray,¹ B. Shelton,¹ R. Reed,¹ P. MacLennan,¹ J. White,¹ D. Eckhoff,¹ R. Allman,² J. Locke.¹
¹University of Alabama at Birmingham, Birmingham; ²Department of Veterans Affairs, Washington DC.
Background: Despite the increasing prevalence of end-stage liver disease (ESLD) in older adults, there is no consensus to determine suitability for liver transplantation (LT) in…
2018 American Transplant Congress
Impact of Early Corticosteroid Treatment in Patients with Indeterminate Acute Severe Hepatitis
E. Mohr,¹ R. Sucher,² T. Müller,³ T. Kaiser,⁴ T. Berg.¹
¹Hepatology, University Clinic Leipzig, Leipzig, Germany; ²Transplant Surgery, University Clinic Leipzig, Leipzig, Germany; ³Hepatology, Charite, Berliin, Germany; ⁴Laboratory Diagnostics, University Clinic Leipzig, Leipzig, Germany.
Background and Aims: Discrimination of acute severe autoimmune hepatitis AIH and drug induced liver injury in patients with indeterminate acute severe Hepatitis is challenging. Early…
2018 American Transplant Congress
Impact of Fluconazole Prophylaxis on Fungal Infections in Liver Transplant Recipients
K. Roach,¹ S. Todd,² M. Lyon,² R. Subramanian.²
¹Lahey Hospital and Medical Center, Burlington, MA; ²Emory University Hospital, Atlanta, GA.
The purpose of this study was to assess if utilizing fluconazole for prophylaxis of invasive fungal infections (IFIs) in high risk liver transplant recipients is…
2018 American Transplant Congress
Serum Beta-(1,3)-D-Glucan as a Case-Finding Tool during an Outbreak of Pneumocystitis jirovecii Pneumonia in Abdominal Transplant Patients
J. Mittal, J. Mogollon, K. Cowman, P. Nori, V. Muggia, G. Minamoto, Y. Puius.
Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY.
Background: Pneumocystis jirovecii pneumonia(PJP) in solid organ transplant (SOT) recipients carries significant morbidity and mortality. There is mounting evidence for ongoing risk of PJP in…
2018 American Transplant Congress
Modified Protocol for ABO-Incompatible Living Donor Liver Transplantation with Rituximab and Intravenous Immunoglobulin without Plasma Exchange
B-.G. Na, E. Lee, S. Kim, S. Park.
Center for Liver Cancer, National Cancer Center, Il-san Donggu, Goyang, Republic of Korea.
Purpose: Since a variety of desensitization strategies including rituximab, intravenous immunoglobulin (IVIG), and plasma exchange (PE) have been introduced, the survival and outcomes of recipients…
2018 American Transplant Congress
Exosomes from Umbilical Cord-Derived Mesenchymal Stem Cells on Hepatocytes Proliferation after Small-for-Size Liver Transplantation via RHO/ROCK Pathway
L. Chen, J. Zheng, J. Cai, J. Yao, K. Zeng, Y. Zhang, Y. Yang.
Department of Liver Transplantation, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Exosomes from umbilical cords-derived mesenchymal stem cells (UC-MSCs-Ex) have been recognized as their ability to promote tissue regeneration in many animal models. However, the in…
2017 American Transplant Congress
Normothermic Regional Perfusion of Donors Following Circulatory Death Improves Outcomes in Liver Transplantation.
E. Mowlem,¹ L. Randle,² C. Fear,¹ K. Crick,¹ S. Messer,⁴ S. Large,⁴ A. Butler,³ C. Watson.³
¹Cambridge Transplant Unit, Addenbrookes Hospital, Cambridge, United Kingdom; ²OrganOx Ltd, Oxford, United Kingdom; ³Dept of Surgery, University of Cambridge, Cambridge, United Kingdom; ⁴Papworth Hospital, Cambridge, United Kingdom
Introduction: Donation after Circulatory Death (DCD) provides 23% of UK livers for transplantation, but such transplants are associated with more primary graft function and early…
2017 American Transplant Congress
Clinical Evaluation of the Safety and Preliminary Efficacy of Continuous Infusion of Treprostinil to Prevent Ischemia and Reperfusion Injury in Adult Orthotopic Liver Transplant Recipients.
O. Almazroo,¹ M. Miah,¹ V. Pillai,¹ A. Humar,² A. Tevar,² C. Hughes,² A. AlKhafaji,³ A. Demetris,⁴ S. Dermont,² S. Fedorek,² H. Johnson,¹ R. Lopez,² R. Planinsic,² B. Sengupta,² I. Sethu,² M. Sturdevant,² S. Ziobert,¹ R. Venkataramanan.^1,2,4
¹Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA; ²Thomas Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; ³Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA; ⁴Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA
Introduction:Liver transplantation is currently the only therapeutic option for patients with end stage liver diseases. Liver allografts undergo cold ischemic injury and warm reperfusion injury…
2017 American Transplant Congress
Community Health, Center Proximity, and Liver Transplant Waitlist Mortality.
R. Lynch,¹ K. Ross,¹ D. Goldberg,² R. Patzer.¹
¹Surgery, Emory University, Atlanta, GA; ²Medicine, University of Pennsylvania, Philadelphia, PA
Background: While regional organ availability is frequently discussed in allocation policy, the impact of community-level factors and access to a transplant center on waitlist mortality…
2017 American Transplant Congress
The Combined Effects of Induction Regimens and Antiviral Prophylaxis on the Risk of CMV Infection in Different Serostatus Subgroups After Liver Transplantation.
C. Low,² S. Hosseini-Moghaddam,^1,2 C. Rotstein,² E. Renner,² A. Humar,² D. Kumar,² S. Husain.²
¹Medicine, Western University, London Health Sciences Centre, London, Canada; ²University Health Network, Toronto, Canada
Introduction: Simultaneous effects of anti-CMV prophylaxis and induction regimens on cytomegalovirus (CMV) infection after liver transplantation (LTRs) have not been studied. We determined the magnitude…