ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2018 American Transplant Congress

    Liver Transplant Patients with MELD>50 at Listing Have Poor Waitlist Outcomes and Similar Post Transplant Survival to Status 1A Patients

    M. Safwan, R. Schilke, U. Nwagu, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai.

    Henry Ford Health System, Detroit, MI.

    Background: Allocation of liver allografts is prioritized to Status 1A patients over end-stage liver disease patients. We aimed to analyze waitlist and transplant outcomes of…
  • 2018 American Transplant Congress

    Donor and Procedural Variability in DCD Liver Transplant: Is It Time to Come to a Consensus?

    L. Ruffolo, M. Balceniuk, R. Hernandez Alejandro.

    Department of Surgery, University of Rochester Medical Center on Behalf of the IDOL Consortium, Rochester, NY.

    Background:Donation after cardiocirculatory death liver transplantation (DCD LT) has re-emerged in part because of insufficient grafts for patients on waiting lists. Unfortunately, DCD LT has…
  • 2018 American Transplant Congress

    A Review of Pediatric Drug Development Programs and FDA Labeling for Immunosuppressive Drugs in Organ Transplant Patients

    G. Burckart,1 M. Cavaillé-Coll,2 A. Duong,3 L. Hothem,4 R. Albrecht.2

    1Office of Clinical Pharmacology, Office of Translational Science, CDER, US Food and Drug Administration, Silver Spring, MD; 2Division of Transplant and Opthalmology Products, Office of New Drugs, CDER, US Food and Drug Administration, Silver Spring, MD; 3Tauro University, New York, NY; 4University of North Carolina, Chapel Hill, NC.

    The development of drugs for organ transplantation spanned the time before and after pediatric regulatory requirements under the Best Pharmaceuticals for Children Act (BPCA) and…
  • 2018 American Transplant Congress

    Donor-to-Recipient Weight Ratio is Significantly Associated with Hepatic Artery Thrombosis Following Pediatric Whole Liver Transplantation

    S. Kim, G. Ramos-Gonzalez, Z. Labib, H. Kim, K. Vakili.

    Surgery, Boston Children's Hospital, Boston, MA.

    Background: Hepatic artery thrombosis (HAT) following pediatric liver transplantation is associated with increased morbidity and risk of graft failure. In our clinical practice, we have…
  • 2018 American Transplant Congress

    Single Center Experience of HLA-Related Donor Specific Antibody in Living Donor Liver Transplantation

    H. Egawa,1 Y. Kotera,1 A. Ohmori,1 S. Yamashita,1 T. Kato,1 S. Nemoto,1 T. Ishizuka,2 M. Yamamoto.1

    1Surgery, Tokyo Women's Medical University, Tokyo, Japan; 2Clinical Laboratory, Tokyo Women's Medical University, Tokyo, Japan.

    Although impact of donor specific antibody in liver transplantation has been recognized, significance of desensitization is not established yet. Our aim is to share our…
  • 2018 American Transplant Congress

    Hospitalization and Life Support before Liver Transplantation – Easily Available Predictors for Post-Transplant Patient Survival

    L. Wiering, P. Ritschl, M. Hippler-Benscheidt, F. Aigner, M. Biebl, D. Eurich, M. Schmelzle, I. Sauer, K. Kotsch, J. Pratschke, R. Öllinger.

    Chirurgische Klinik Campus Charité Mitte / Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Berlin, Germany.

    IntroductionCurrently liver allocation -in contrast to allocation of other organs- is based on urgency in many countries and survival benefit is not included. Aim of…
  • 2017 American Transplant Congress

    Efficacy and Safety of Everolimus with Reduced Tacrolimus or Cyclosporine in Pediatric Liver Transplant Recipients: 12-Month Results from H2305 Study.

    A. Weymann,1 R. Ganschow,1 B. Ericzon,1 A. Dhawan,1 K. Sharif,1 E.-D. Martzloff,2 B. Rauer,2 J. Ng,2 P. Lopez.2

    1H2305 Study Group, St Louis; 2Novartis Pharma AG, Basel, Switzerland

    Purpose: Everolimus (EVR) facilitated calcineurin inhibitor (CNI) reduction has shown improved renal function (RF) without compromising efficacy in adult liver transplant recipients (LTxR). Here we…
  • 2017 American Transplant Congress

    Contemporary Outcomes and Risk Factors of Acute Graft-versus-Host Disease After Liver Transplant.

    J. Markus, A. Bukannan, B. Kashat, R. Salgia.

    Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI

    Introduction:Acute graft-versus-host-disease (GVHD) is a rare complication of orthotopic liver transplant (LT) that has an estimated incidence of 0.1%-2% per year. This complication of OLT…
  • 2017 American Transplant Congress

    Live Donor Liver Transplantation Using Grafts with More Than Two Bile Ducts – Does It Affect Patient Outcome?

    D. Kollmann, G. Sapisochin, N. Selzner, M. Cattral, P. Greig, L. Lilly, I. McGilvray, A. Ganekar, D. Grant, M. Selzner, N. Goldaracena.

    Multi Organ Transplant Program, Department of Surgery, Toronto General Hospital, Toronto, ON, Canada

    Introduction: It's been described that the use of live donor (LD) liver grafts with multiple bile ducts (BD) increases the risk of BD related complications…
  • 2017 American Transplant Congress

    B Cells in Liver Transplant Tolerance.

    M. Morita,1 G. Asonye,1 N. Gupta,1 J. Fung,2 C. Miller,3 S. Qian,1,3 L. Lu.1,3

    1Immunology, Cleveland Clinic, Cleveland; 2University of Chicago, Chicago, MI; 3General Surgery, Cleveland Clinic, Cleveland, OH

    In mice liver transplantation, the liver allografts can be accepted across fully mismatched MHC without immunosuppression. After transplantation, T cells infiltrate into the graft in…
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