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American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2018 American Transplant Congress

    Opiate Use Trends after Liver Transplantation and the Factors Associated with Post-Transplant Opiate Dependence

    M. Siddiqui,1 R. Kaur,1 S. Dhoop,2 N. Sulejmani,1 R. Salgia.1

    1Henry Ford Hospital, Detroit, MI; 2Wayne State University SOM, Detroit, MI.

    AimsOur study aims to determine predictive factors leading to post-liver transplant (LT) opioid dependence.MethodsA retrospective chart review was conducted including LT recipients from July 2013-June…
  • 2018 American Transplant Congress

    Pharmacological Defatting of Steatotic Human Livers Using a Novel Perfusion Solution during Normothermic Machine Perfusion

    Y. Boteon,1,2 J. Attard,1,2 R. Laing,1,2 A. Boteon,1 R. Bhogal,1 G. Reynold,2 D. Neil,1 H. Mergental,1 D. Mirza,1 S. Afford.2

    1National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; 2Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.

    Introduction: Steatosis is the leading reason for donor livers discarding and contributes significantly to the worsening shortage of organs for transplantation. Steatotic livers commonly fail…
  • 2018 American Transplant Congress

    Clostridium Difficile Infection after Liver Transplant is Associated with Poor Long-Term Survival

    A. Ahearn, P. Mahboub, N. Theodoropoulos, B. Movahedi, P. Martins, M. Campion, R. Nathan, A. Bozorgzadeh.

    Division of Organ Transplantation, Umass Memorial Medical Center, Worcester, MA.

    Background: Clostridium Difficile infection (CDI) is a growing problem in hospitalized patients and occurs in liver transplant recipients at a higher rate than non-transplant patients.…
  • 2018 American Transplant Congress

    Skeletons in the Closet? An Insight into Donor Liver Discards in the US

    K. Halazun, A. Rana, G. Roll, P. Tabrizian, V. Agopian, B. Samstein, R. Brown, J. Emond.

    Weill Cornell Medicine, NY, NY.

    Background Liver discards are poorly investigated. Among these discarded livers are potentially useable grafts that could save the lives of many of the 2500-3000 who…
  • 2018 American Transplant Congress

    Waitlist Outcomes and Access to Liver Transplantation for HIV+ Candidates

    A. Shaffer,1 A. Thomas,1 A. Massie,1 S. Gustafson,2 J. Snyder,2 B. Shelton,3 R. Reed,3 J. Locke,3 D. Segev,1,2 C. Durand.1

    1JHU, Baltimore; 2SRTR, Minneapolis; 3UAB, Birmingham.

    Liver disease is a leading cause of death for HIV+ individuals, and the number of HIV+ liver transplant recipients is increasing. However, since UNOS does…
  • 2018 American Transplant Congress

    ADL and IADL Limitations Resolve but New Cognitive Impairments Develop in Liver Transplant Recipients

    J. Corriveau, R. Chandrasekhar, S. Geevarghese.

    Vanderbilt University School of Medicine, Nashville.

    Introduction: Survivors of critical illness often have prolonged cognitive and functional impairments, and suffer from depression and PTSD. This constellation of symptoms is termed post-intensive…
  • 2018 American Transplant Congress

    Liver Transplant Patients with MELD>50 at Listing Have Poor Waitlist Outcomes and Similar Post Transplant Survival to Status 1A Patients

    M. Safwan, R. Schilke, U. Nwagu, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai.

    Henry Ford Health System, Detroit, MI.

    Background: Allocation of liver allografts is prioritized to Status 1A patients over end-stage liver disease patients. We aimed to analyze waitlist and transplant outcomes of…
  • 2018 American Transplant Congress

    Donor and Procedural Variability in DCD Liver Transplant: Is It Time to Come to a Consensus?

    L. Ruffolo, M. Balceniuk, R. Hernandez Alejandro.

    Department of Surgery, University of Rochester Medical Center on Behalf of the IDOL Consortium, Rochester, NY.

    Background:Donation after cardiocirculatory death liver transplantation (DCD LT) has re-emerged in part because of insufficient grafts for patients on waiting lists. Unfortunately, DCD LT has…
  • 2018 American Transplant Congress

    A Review of Pediatric Drug Development Programs and FDA Labeling for Immunosuppressive Drugs in Organ Transplant Patients

    G. Burckart,1 M. Cavaillé-Coll,2 A. Duong,3 L. Hothem,4 R. Albrecht.2

    1Office of Clinical Pharmacology, Office of Translational Science, CDER, US Food and Drug Administration, Silver Spring, MD; 2Division of Transplant and Opthalmology Products, Office of New Drugs, CDER, US Food and Drug Administration, Silver Spring, MD; 3Tauro University, New York, NY; 4University of North Carolina, Chapel Hill, NC.

    The development of drugs for organ transplantation spanned the time before and after pediatric regulatory requirements under the Best Pharmaceuticals for Children Act (BPCA) and…
  • 2018 American Transplant Congress

    Donor-to-Recipient Weight Ratio is Significantly Associated with Hepatic Artery Thrombosis Following Pediatric Whole Liver Transplantation

    S. Kim, G. Ramos-Gonzalez, Z. Labib, H. Kim, K. Vakili.

    Surgery, Boston Children's Hospital, Boston, MA.

    Background: Hepatic artery thrombosis (HAT) following pediatric liver transplantation is associated with increased morbidity and risk of graft failure. In our clinical practice, we have…
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