Articles tagged "Liver transplantation"

2018 American Transplant Congress
Impact of Positive Donor Blood Cultures in Liver Transplant Recipients
D. Bley, D. Lo, G. Lyon III, R. Subramanian, S. Todd.
Emory University Hospital, Atlanta, GA.
The purpose of this study was to describe the bacteremia transmission rate of transplanting livers from donors with positive bacterial blood cultures into liver transplant…
2018 American Transplant Congress
Preoperative Antibiotics Treatment Decreases Endoplasmic Reticulum Stress and Protects Liver Transplant from Ischemia-Reperfusion Injury
T. Ito, F. Kaldas, K. Nakamura, S. Kageyama, A. Aziz, R. Busuttil, J. Kupiec-Weglinski.
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA.
Ischemia-reperfusion injury (IRI) represents a major risk factor of graft dysfunction in liver transplantation (LT). We have reported a critical role of endoplasmic reticulum (ER)…
2018 American Transplant Congress
Single-Dose Basiliximab Induction in Liver Transplant Recipients with Delayed CNI Initiation
D. Salerno,¹ N. Lange,¹ R. Rosenblatt,² C. Sammons,³ B. Fortune.²
¹Pharmacy, NewYork-Presbyterian Hospital, New York, NY; ²Medicine, Weill Cornell Medicine, New York, NY; ³Pharmacy, Hospital of the University of Pennsylvania, Philadelphia, PA.
Liver transplant recipients (LTR) with peri-operative renal injury benefit from a delayed CNI protocol using basiliximab (IL2RA) induction to reduce early CNI exposure. Existing literature…
2018 American Transplant Congress
Impact of Preserved Collateral Veins on Small-for-Size Grafts in Living Donor Liver Transplantation
B-.G. Na, E. Lee, S. Kim, S. Park.
Center for Liver Cancer, National Cancer Center Research Institute, Goyang, Republic of Korea.
Purpose: Graft size is a critical issue in living donor liver transplantation (LDLT). We hypothesized that too much portal flow could possibly be diverted into…
2018 American Transplant Congress
Clinical Application of Mesenchymal Stromal Cells with a Simplified Protocol for ABO Incompatible Liver Transplantation in Severe Hepatic Failure Patients
Y. Zhang,^1,2 J. Zheng,^1,2 J. Cai,^1,2 J. Zhang,^1,2 K. Zeng,^1,2 J. Yao,^1,2 Y. Yang.^1,2
¹Department of Hepatic Surgery and Liver Transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Guangzhou, Guangdong, China; ²Guangdong Key Laboratory of Liver Disease Research, Key Laboratory of Liver Disease Biotherapy and Translational Medicine of Guangdong Higher Education Institutes, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, .
Objective The purpose of this study was to test the safety and efficacy of mesenchymal stromal cells (MSCs) treatment with a simplified protocol for ABO…
2018 American Transplant Congress
Normothermic Machine Perfusion (NMP) Preservation for Human Liver Transplantation in the Cleveland Clinic
Q. Liu, D. Pezzati, A. Hassan, B. Soliman, P. Grady, S. Maikhor, G. Iuppa, T. Diago Uso, K. Hashimoto, F. Aucejo, M. Fujiki, B. Eghtesad, J. Cywinski, S. Irefin, J. Fung, K. Abu-Elmagd, C. Miller, C. Quintini.
Cleveland Clinic, Cleveland, OH.
NMP is a novel preservation method for liver grafts. We transplanted 15 human livers after NMP to test the safety and feasibility of NMP on…
2018 American Transplant Congress
Serelaxin-Notch1 Signaling Promotes Macrophage M2 Differentiation and Alleviates Hepatocellular Damage in Orthotopic Liver Transplantation: From Mouse-to-Human
S. Kageyama,¹ K. Nakamura,¹ B. Ke,¹ R. Sosa,² E. Reed,² F. Kaldas,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Liver Transplant, UCLA, Los Angeles, CA; ²Pathology, UCLA, Los Angeles, CA.
Background/Aim: We have documented crucial role of macrophage Notch1 signaling in a mouse warm hepatic ischemia-reperfusion injury (IRI) model. However, its clinical relevance or therapeutic…
2018 American Transplant Congress
Examples of the Observer Effect in Transplantation- Unintended Consequences of Regulation and Selected Outcome Metrics
A. Rana, M. Kueht, N. Galvan, R. Cotton, C. O'Mahony, J. Goss.
Abdominal Transplantation, Baylor College of Medicine, Houston, TX.
Introduction: The influence of an observer on the phenomena being observed is designated as the observer effect. It is our aim to demonstrate that an…
2018 American Transplant Congress
Effect of HLA Antibodies on Graft Survival in Adult Live Donor Liver Transplantation
M. Simpson,¹ M. Akoad,¹ F. Gordon,¹ Y-.L. Cheah,¹ C. Simon,¹ J. Pomposelli,² E. Pomfret.²
¹Transplantation, Lahey Hospital & Medical Center, Burlington, MA; ²Transplantation, University of Colorado Medical Center, Aurora, CO.
The relevance of HLA antibodies in liver transplantation is currently being re-evaluated. While hyperacute rejections are not an issue, antibody effects on long-term outcomes are…
2018 American Transplant Congress
Liver Retransplantation and Renal Failure: The Benefit of Simultaneous Kidney Transplant
J. Berumen,¹ V. Irine,² S. Mita,² S. Gabriel,¹ M. Kristin.¹
¹Department of Surgery, University of California San Diego, San Diego, CA; ²Department of Medicine, University of California San Diego, San Diego, CA.
Liver retransplantation has poor survival compared to primary liver transplant. Renal failure is a proven negative risk factor for survival with retransplant. Our aim was…