2022 American Transplant Congress
Single Cell RNAseq Analysis of Liver Transplant Rejection Reveals Highly Restricted TCR Clonal Expansion of Tissue-Resident Memory CD8+ T Cells That Persist Despite Corticosteroids and ATG Therapy
*Purpose: Conventional therapy for liver transplant rejection (corticosteroids and ATG) has remained unchanged for six decades, and is not infrequently met with treatment failure. Here,…2022 American Transplant Congress
Variation in Donor Liver Rejection Rates for Donor Quality Among US Transplant Centers
*Purpose: Optimal utilization of all viable donor livers is a public health imperative. As no standardized criteria exist for assessment of donor quality, differential utilization…2022 American Transplant Congress
Impaired Left Ventricular Global Longitudinal Strain: Clinical Presentation and Outcomes in Liver Transplantation Recipients without Arrhythmia or Structural Heart Disease
University of Maryland School of Medicine, Baltimore, MD
*Purpose: Assess the prevalence and characteristics of patients without arrhythmia or structural heart disease (SHD) but with impaired pre-transplant left ventricular global longitudinal strain (GLS)…2022 American Transplant Congress
Area Deprivation Index is Associated with Worse Patient Survival Following Adult Liver Transplantation
*Purpose: Area Deprivation Index (ADI) has been utilized as a granular measure of local socioeconomic status for nearly two decades. This study is the first…2022 American Transplant Congress
Liver Transplantation Outcomes for Budd-Chiari Syndrome in the MELD Era
*Purpose: Budd Chiari syndrome (BCS) has a heterogeneous clinical presentations ranging from asymptomatic cases to fulminant liver failure with significant morbidly and mortality. Recent data…2022 American Transplant Congress
Improving Access and Equity for Transplant: A Single-Center Experience
*Purpose: Many Hispanic Americans have misconceptions about transplantation due to language and cultural differences, which can make them less likely to undergo liver transplant (LT)…2022 American Transplant Congress
Racial/Ethnic Disparities in Rates of Living Donor Liver Transplant Are Partly Explained by Socioeconomic Deprivation in Adults
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Living donor liver transplant (LDLT) is an important strategy for addressing the deceased donor liver shortage and is associated with improved survival but represents…2022 American Transplant Congress
Pretransplant Rifaximin Treatment Improves Liver Transplant Outcomes in Mice and Humans
UCLA Medical Center, Los Angeles, CA
*Purpose: We recently reported modifications of the gut microbiota by amoxicillin influences liver allograft function. Rifaximin (RFX), a nonabsorbable oral antimicrobial agent with a low…2022 American Transplant Congress
Analysis of Tissue and Effluent Damage Associated Molecular Patterns Following Hypothermic Oxygenated Machine Perfusion vs Static Cold Storage in Liver Transplantation
Transplant Surgery, Rutgers New Jersey Medical School, Newark, NJ
*Purpose: Hypothermic Oxygenated Machine Perfusion (HMP-O2) results in decreased ischemia/reperfusion injury (IRI) after liver transplantation; however, the molecular pathways of protection are largely unexplored. In…2022 American Transplant Congress
Early Experiences with Developing the Techniques of Pure Laparoscopic Explant Hepatectomy without Fragmentation in Living Donor Liver Transplantation
*Purpose: Minimally invasive surgery is increasingly performed in liver surgery including even donor hepatectomy. However, the development of minimally invasive techniques in liver transplantation has…
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