Articles tagged "Liver transplantation"

2022 American Transplant Congress
Meld Score <31 Predicts Spontaneous Recovery in Patients Listed for Liver Transplantation for Alcohol-Associated Hepatitis: A UNOS Database Study
Y. Bekki, G. Im, T. Schiano, S. Florman
Icahn School of Medicine at Mount Sinai, RMTI, New York, NY
*Purpose: Alcohol-associated hepatitis (AH) is the fastest growing indication for liver transplantation (LT) in the U.S. While spontaneous recovery (SR) can occur in patients with…
2022 American Transplant Congress
Artificial Intelligence Based Dosing of Tacrolimus in Liver Transplantation: Prospective, Randomized Phase 2 Trial
A. Zarrinpar¹, C. Ho², C. Warren¹, J. Khong², M. Lee², S. Duarte¹, K. Andreoni¹, M. Johnson¹, N. Battula³, D. McKimmy¹, T. Beduschi¹
¹Surgery, University of Florida, Gainesville, FL, ²Mechanical and Aerospace Engineering, University of California, Los Angeles, CA, ³Surgery, University of Oklahoma, Oklahoma City, OK
*Purpose: Inter- and intra-individual variability in calcineurin dose requirements necessitates empirical clinician-titrated dosing that frequently results in deviation from target ranges, particularly during the critical…
2022 American Transplant Congress
Post-Operative Day 1 Galectin-3 is Predictive of Early Allograft Dysfunction in Liver Transplantation
D. Yoeli, T. Ferrell, I. Rodriguez, N. Limon De La Rosa, N. Nakra, Z. Wang, E. Cervantes-Alvarez, R. Choudhury, M. Adams, T. Nydam, E. Pomfret, C. Huang, N. Navarro Alvarez, H. Moore
University of Colorado Anschutz Medical, Aurora, CO
*Purpose: Early allograft dysfunction (EAD) is an important outcome measure in liver transplantation that is predictive of graft failure, but the mechanism behind it remains…
2022 American Transplant Congress
Detection of Early Graft Injury After Liver Transplantation with Blood-Bile Ratio of Tacrolimus: The TUBE Trial
M. M. Pascale¹, G. Bianco¹, L. Ferri¹, F. Giovinazzo¹, A. Liguori², G. Marrone², A. Grieco², S. Agnes¹
¹General Surgery and Liver Transplant Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy, ²Transplant Hepatology Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy
*Purpose: The aim of the“Tacrolimus in Bile”(TUBE)Trial is the creation of a laboratory parameter for the early detection of hepatic injury after liver transplant.*Methods: TUBE…
2022 American Transplant Congress
Predictive Value of Abnormal Hemodynamic Response to Dobutamine Stress Echocardiography in Liver Transplant Recipients
M. Groose, A. Peotter, L. Hammel
University of Wisconsin Hospitals and Clinics, Madison, WI
*Purpose: Dobutamine stress echocardiography (DSE) is an effective tool for perioperative cardiac risk stratification in patients without end-stage liver disease (ESLD). However, DSE is frequently…
2022 American Transplant Congress
An In Depth Assessment of Unsuccessful DCD Donor Procurement Attempts: Areas for Improvement
M. Rosenzweig, M. Finotti, E. Martinez, S. Lee, A. Gupta, A. Wall, J. Bayer, H. Fernandez, N. Onaca, R. Ruiz, G. J. McKenna
Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX
*Purpose: DCD donors are a key way to expand allograft supply but an aggressive strategy of pursuing DCD liver allografts is associated with significant number…
2022 American Transplant Congress
Pulmonary Function Tests and Liver Transplantation
D. Reino¹, P. Martinez², K. Robichaux³, M. Gosselin⁴, S. Mohammed³, J. Buggs¹, A. Kumar⁵
¹Transplant Surgery, Tampa General Hospital, Tampa, FL, ²University of Miami, Miami, FL, ³University of South Florida, Tampa, FL, ⁴University of Tampa, Tampa, FL, ⁵Morsani College of Medicine, University of South Florida, Tampa, FL
*Purpose: Liver transplant recipients have a high risk of developing postoperative pulmonary complications. Pulmonary function tests (PFTs) are expensive and often incapable of predicting patients…
2022 American Transplant Congress
Role of Circulating Tumour Cells in the Management of the Liver Transplant Patient with Hepatocellular Carcinoma
F. Villalba¹, F. Alconchel², L. Sáenz³, M. Sánchez-Lorencio¹, D. Ferreras², P. Cascales², F. Sánchez-Bueno², R. Robles², P. Ramírez²
¹IMIB-Virgen de la Arrixaca, Murcia, Spain, ²Surgery and Organ Transplantation, Virgen de la Arrixaca University Hospital (IMIB-Virgen de la Arrixaca), Murcia, Spain, ³Rafael Méndez Hospital, Lorca, Spain
*Purpose: For hepatocellular carcinoma (HCC), liver transplantation (LT) is considered a curative treatment, however, more than 10% of transplant recipients have recurrences within the first…
2022 American Transplant Congress
Combined Heart-Liver Transplantation for Failing Fontan Physiology: A Large Single Center Comparative Analysis
C. J. Rosenthal¹, D. Noguchi¹, J. A. Aboulhosn², G. S. Van Arsdell³, A. Nsair⁴, M. Ha¹, L. Reardon², G. Lluri⁴, J. P. Lin⁴, S. Saab¹, A. Baird¹, R. S. Venick¹, D. G. Farmer¹, F. M. Kaldas¹
¹Liver and Pancreas Transplant Center, UCLA, Los Angeles, CA, ²Ahmanson/UCLA Adult Congenital Heart Disease Center, UCLA, Los Angeles, CA, ³Cardiac Surgery, UCLA, Los Angeles, CA, ⁴Cardiology, UCLA, Los Angeles, CA
*Purpose: The rate of combined heart-liver transplantation (HLT) has tripled in the last decade, and continues to rise along with the number of patients with…
2022 American Transplant Congress
Basiliximab Provides Similar Efficacy and Renal Recovery in Steroid-Minimal Liver Transplantation
L. Bowman¹, A. Webb¹, Y. Alsalihi², F. Fakhre³, R. Baliga⁴, V. Subramanian⁵, K. Robichaux³, S. Mohammed³, M. Gosselin⁶, J. Buggs⁵, A. Kumar⁷
¹Transplant Pharmacy, Tampa General Hospital, Tampa, FL, ²California Health Sciences University, Clovis, CA, ³University of South Florida, Tampa, FL, ⁴Florida Kidney Physicians, Tampa, FL, ⁵Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁶University of Tampa, Tampa, FL, ⁷Morsani College of Medicine, University of South Florida, Tampa, FL
*Purpose: Due to nephrotoxic effects of tacrolimus, previous studies have evaluated the utility of basiliximab to delay or reduce tacrolimus for renal preservation in orthotopic…