Articles tagged "Liver transplantation"

2018 American Transplant Congress
Hyaluronic Acid as Early Biomarker of Graft Loss after Liver Transplantation: A Prospective Study
A. Rostved,¹ S. Ostrowski,² L. Peters,³ J. Lundgren,³ C. Sørensen,¹ H-.C. Pommergaard,¹ J. Hillingsø,¹ A. Rasmussen.¹
¹Department of Surgical Gastroenterology and Transplantation, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; ²Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; ³CHIP, Department of Infectious Diseases, Section 2100, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Introduction: Improved diagnosis and understanding the pathophysiology of early allograft dysfunction is essential to improve the short-term outcome after liver transplantation (LT). Hyaluronic acid (HA)…
2018 American Transplant Congress
Evaluation the Outcomes of Liver Transplant Recipients Underwent Splenectomy: A Meta-Analysis
M. Chen, X. Lin, B. Huang, X. He.
Organ Transplant Center, Sun yat-sen University, Guangzhou, China.
Background. Splenectomy is performed as strategy of modulating the portal vein pressure in most of portal hypertension patients with liver cirrhosis. In liver transplantation, researchers…
2018 American Transplant Congress
DCD Utilization in Cholestatic Liver Disease: Distinct Outcomes between PSC and PBC Recipients
J. Pasko, E. Maynard, E. Dewey, K. Roayaie, S. Orloff, D. Scott, W. Naugler, J. Ahn, C. Enestvedt.
Abdominal Transplant Surgery, Oregon Health & Science University, Portland, OR.
Background: Concern for inferior outcomes in patients with primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) have limited utilization of donation after cardiac death…
2018 American Transplant Congress
Financial Impact of Testing Standardization for Solid Organ Transplant Recipients
S. Ugolini,² L. Dranow,¹ P. Sadler,² M. Berry,² J. Stehlik,¹ S. Drakos,¹ J. Nativi,¹ E. Gilbert,¹ S. McKeller,¹ A. Koliopoulou,¹ M. Yin,¹ E. Davis,² C. Selzman,¹ O. Wever-Pinzon.¹
¹Division of Cardiology, University of Utah Health, Salt Lake City, UT; ²Transplant Service Line, University of Utah Health, Salt Lake City, UT.
Background: Infection and bone marrow suppression surveillance is common practice in transplant recipients. Ordering of inappropriate lab tests can lead to repetitive blood draws, higher…
2018 American Transplant Congress
Liver Transplantation for Hepatocellular Carcinoma Outperform Other Populations in the New Hepatitis C Era
A. Alsina,¹ A. Athienitis,² J. Buggs,¹ E. Fallon,³ E. Parkinson,³ C. Albers,³ N. Kemmer.³
¹Transplantation Surgery, Tampa General Hospital, Tampa, FL; ²Muma College of Business, University of South Florida, Tamoa, FL; ³Transplant Hepatology, Tampa General Hospital, Tampa, FL.
Background: Long term results of HCC liver transplants (LTx) in the recent era of direct-acting antivirals (DAA) against hepatitis C (HCV) are not available. We…
2018 American Transplant Congress
Dual Function of IRF1/IRF4 on Dendritic Cells in Mouse Liver Transplantation Model
G. Gu, T. Lu, N. Xu, Q. Xia.
Department of Liver Surgery, Renji Hospital, Affiliated by Shanghai Jiaotong University School of Medicine, Shanghai, China.
Tolerogenic dendritic cells play an essential role in transplant tolerance induction. However, how to induce tolerogenic dendritic cells is not fully understood. Here, we sorted…
2018 American Transplant Congress
Clinical Impact of Antecedent Bariatric Surgery on Liver Transplant Outcomes: A Retrospective Matched Case-Control Study
O. Serrano,¹ K. Peterson,¹ D. Vock,² D. Berglund,¹ R. Kandaswamy,¹ J. Lake,³ T. Pruett,¹ S. Chinnakotla.¹
¹Surgery, University of Minnesota, Minneapolis, MN; ²Biostatistics, University of Minnesota, Minneapolis, MN; ³Medicine, University of Minnesota, Minneapolis, MN.
OBJECTIVE: Bariatric surgery (BS) is associated with significant malabsorption and nutritional deficiencies, which can have profound consequences on the liver transplant (LT) patient. The magnitude…
2018 American Transplant Congress
National Landscape of HIV+ Liver Transplant Candidates
A. Shaffer,¹ A. Thomas,¹ A. Massie,¹ S. Gustafson,² J. Snyder,² B. Shelton,³ R. Reed,³ J. Locke,³ D. Segev,¹ C. Durand.¹
¹JHU, Baltimore; ²SRTR, Minneapolis; ³UAB, Birmingham.
The annual number of HIV+ liver transplant (LT) recipients has increased >10-fold since 2002. However, candidate HIV-status is not collected by UNOS, and the national…
2018 American Transplant Congress
Graft CEACAM1 is Essential to Autophagy Induction and T-Cell Regulation in Liver Transplantation: From Mouse-to-Human
K. Nakamura,¹ S. Kageyama,¹ M. Kujawski,² T. Ito,¹ A. Aziz,¹ D. Oncel,¹ B. Ke,¹ R. Sossa,³ E. Reed,³ F. Kaldas,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Liver Transplant, UCLA, Los Angeles, CA; ²Molecular Immunology, City of Hope, Duarte, CA; ³Pathology, UCLA, Los Angeles, CA.
We have documented crucial role of TIM-3 dependent T cell dysfunction in mouse orthotopic liver transplantation (OLT). CEACAM1 (CM1; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1),…
2018 American Transplant Congress
Transplantation of DCD Livers vs. NDD and LDLT: Is There a Difference in Post-Transplant Kidney Dysfunction?
D. Kollmann,¹ S. Neong,¹ R. Rosales,¹ G. Sapisochin,¹ M. Bhat,¹ M. Cattral,¹ P. Greig,¹ L. Lilly,¹ D. McGilvray,¹ A. Ghanekar,¹ D. Grant,¹ M. Selzner,¹ F. Wong,² N. Selzner.¹
¹Multi Organ Transplant, Toronto General Hospital, Toronto, Canada; ²Division of Gastroenterology, Toronto General Hospital, Toronto, Canada.
Background. Recipients of donation after circulatory death (DCD) grafts are reportedly at higher risk of developing post liver transplant (LT) renal dysfunction. Our aim was…