Articles tagged "Liver transplantation"

2018 American Transplant Congress
Effects of the Addition of Mycophenolate Mofetil on Renal Outcomes in Liver Transplant Recipients: A Single Center Review
M. Henry, M. Vacha.
Nebraska Medicine, Omaha, NE.
Purpose: To evaluate the use of mycophenolate mofetil (MMF) and its effects on renal outcomes in liver transplant recipientsMethods: Adult liver transplant recipients from September…
2018 American Transplant Congress
Impact of Aortic Abdominal Calcification among Living Donor Liver Transplant Recipients; a Retrospective Study
Y. Imaoka, M. Ohira, S. Simizu, H. Tahara, K. Ide, Y. Tanaka, H. Ohdan.
Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.
Abdominal aortic calcification (AAC) is known as a risk factor of coronary artery disease, stroke, hyperphosphatemia, chronic inflammation, diabetes, and decreased an estimated glomerular filtration…
2018 American Transplant Congress
Efficacy of Two Valganciclovir Dosing Strategies in Intermediate and High-Risk Liver Transplant Recipients
K. Belfield,¹ M. Malinis,² E. Cohen.¹
¹Department of Pharmacy, Yale New Haven Hospital, New Haven, CT; ²Section of Infectious Diseases, Yale School of Medicine, New Haven, CT.
Purpose: There is interest in reduced dosing and duration of valganciclovir (VGCV) for cytomegalovirus (CMV) prophylaxis in liver transplant (LT) recipients to minimize side effects…
2018 American Transplant Congress
Increased Expression of CEACAM1 is Cytoprotective during Ischemia-Reperfusion Injury in Human Orthotopic Liver Transplantation
R. Sosa,¹ J. Nevarez-Mejia,¹ M. Rossetti,¹ A. Zarrinpar,² F. Kaldas,² C. Lassman,¹ B. Naini,¹ N. Datta,² R. Busuttil,² D. Gjertson,¹ J. Kupiec-Weglinski,² E. Reed.¹
¹Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA; ²Surgery, University of California, Los Angeles, Los Angeles, CA.
Background T cell exhaustion has recently been proposed as an alternative mechanism to prevent memory development and tissue damage arising during ischemia-reperfusion injury (IRI) in…
2018 American Transplant Congress
Midodrine Associated with Increased Mortality on Liver Transplant Waitlist
J. Kalil, M. Hertl, E. Schadde, J. Poirier, N. Alvey, E. Chan.
General Surgery - Transplant, Rush University Medical Center, Chicago, IL.
Background:Midodrine is an alpha-1 agonist which induces arterial and venous vasoconstriction. It prevents symptomatic hypotension and is used for treatment of refractory ascites and hepatorenal…
2018 American Transplant Congress
Living Liver Donation is Safe in Donors Heterozygous for an alpha-1 Antitrypsin Gene Mutation
T. Bittermann,¹ L. Wood,² P. Abt,² A. Shaked,² K. Olthoff,² D. Goldberg.^1,3
¹Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA; ²Division of Transplant Surgery, University of Pennsylvania, Philadelphia, PA; ³Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA.
Patients homozygous for an alpha-1 antitrypsin mutation, particularly the Pi*ZZ phenotype, develop cirrhosis and pulmonary emphysema. Those with a heterozygous phenotype are thought to have…
2018 American Transplant Congress
Hypothermic Machine Perfusion Protects DCD Liver Graft through Metabolism of Xenobiotics by Cytochrome P450 Pathway
Q. Ye,^1,2 W. Liang,¹ Z. Zhong,¹ S. Ye,¹ B. Tang,¹ Q. Hu,¹ J. Liang,¹ Y. Wang.¹
¹Transplant Center of Wuhan University, Zhongnan Hospital of Wuhan University, Wuhan, China; ²The 3rd Xiangya Hospital of Central South Unversity, Changsha, China.
Background: Donation after cardiac death (DCD) is the mainly resource to relieve organ-transplantation shortage. Our previous research have confirmed that the function of DCD liver…
2018 American Transplant Congress
Safety of Antithymocyte Globulin Use in Donation after Circulatory Death (DCD) Liver Transplantation
D. Felix,¹ B. Geiger,¹ J. Descourouez,¹ M. Jorgenson,¹ B. Hanlon,² G. Leverson,² D. Foley.²
¹Department of Pharmacy, UW Health, Madison, WI; ²Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Purpose: Rabbit antithymocyte globulin (rATG) is commonly used for induction immunosuppression and treatment of rejection in solid organ transplantation. Previous work has shown that rATG…
2018 American Transplant Congress
The First Series of Ischemia-Free Liver Transplantation in Human
X. He,¹ Z. Guo,¹ S. Huang,¹ Q. Zhao,¹ Y. Tang,¹ Z. Zhang,¹ Z. Zhu,¹ W. Ju,¹ L. Yang,² G. Chen.¹
¹Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; ²Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
BACKGROUND&AIMS: Ischemia and reperfusion injury (IRI) is known as an inevitable event leading to early and late graft failure. We have performed the first case…
2018 American Transplant Congress
Making Sense of Hepatitis B Reactivation Risk in Anti-HBc Antibody (Ab) Positive Liver Transplant Recipients
S. Leistman,¹ J. Melaragno,¹ M. Dokus,² B. Al-Judaibi,² T. Babu.³
¹Department of Pharmacy, University of Rochester Medical Center, Rochester, NY; ²Division of Transplantation, University of Rochester Medical Center, Rochester, NY; ³Division of Infectious Diseases, University of Rochester Medical Center, Rochester, NY.
Background: Limited data exists regarding the rates of reactivation of hepatitis B virus (HBV) in anti-HBc Ab positive orthotopic liver transplant (OLT) recipients. Protocols vary…