Articles tagged "Liver transplantation"

2018 American Transplant Congress
Exosomes from Umbilical Cord-Derived Mesenchymal Stem Cells on Hepatocytes Proliferation after Small-for-Size Liver Transplantation via RHO/ROCK Pathway
L. Chen, J. Zheng, J. Cai, J. Yao, K. Zeng, Y. Zhang, Y. Yang.
Department of Liver Transplantation, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Exosomes from umbilical cords-derived mesenchymal stem cells (UC-MSCs-Ex) have been recognized as their ability to promote tissue regeneration in many animal models. However, the in…
2018 American Transplant Congress
The Transplant-Death Index: A Novel Method to Identify Disenfranchised Liver Transplant Waitlist Candidates
M. Kueht, J. Goss, N. Galvan, A. Rana.
Surgery, Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX.
The transplant field is seeing a shift in outcome priorities from just 1-year survival to include waitlist metrics such as the transplant rate. Identifying disenfranchised…
2018 American Transplant Congress
Livers from Donation after Circulatory Death Donors Can Be Safely Used for Retransplantation
O. van Leeuwen,¹ M. van Reeven,² J. Erdmann,³ H. Metselaar,⁴ A. van den Berg,⁵ B. van Hoek,⁶ W. Polak,² R. Porte.¹
¹Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; ²Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands; ³Department of Surgery, Leiden University Medical Center, Leiden, Netherlands; ⁴Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, Netherlands; ⁵Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, Netherlands; ⁶Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands.
Introduction: After donation after circulatory death (DCD) liver transplantation (LT), non-anastomotic biliary strictures (NAS) and early allograft dysfunction (EAD) are more frequently observed than after…
2018 American Transplant Congress
Anticoagulation in Pediatric Liver Transplantation; the Pros and Cons
M. Werner,¹ R. de Kleine,¹ M. de Boer,¹ V. de Meijer,¹ R. Scheenstra,² H-.J. Verkade,² F. Bodewes,² S. Bontemps,³ T. Lisman,¹ R. Porte.¹
¹HPB Surgery & Liver Transplantation, University Medical Center Groningen, Groningen, Netherlands; ²Pediatric Gastroenterology & Hepatology, University Medical Center Groningen, Groningen, Netherlands; ³Pediatric Intensive Care, University Medical Center Groningen, Groningen, Netherlands.
Background: Hepatic artery thrombosis (HAT) and portal vein thrombosis (PVT) are serious causes of morbidity and mortality after pediatric orthotopic liver transplantation (OLT). To minimize…
2018 American Transplant Congress
Liver Transplantation Using Pediatric versus Adult Donor Grafts in Adult Recipients
Y. Tang, Q. Zhao, Z. Zhang, L. Wang, W. Ju, Z. Zhu, S. Huang, Z. Guo, X. He, G. Chen.
Organ Transplant Center, Sun Yat-sen University, Guangzhou, Guangdong, China.
Background and Aim: The reported outcomes of adult liver transplantation using pediatric allografts are largely controversial based on single center studies. We aimed to compare…
2018 American Transplant Congress
Medication Reconciliation in Abdominal Transplantation
S. Todd,¹ J. Perryman,² R. Subramanian,² A. Patel,² M. Hawthorne,² R. Buenvenida,² K. Lee,² W. Allison,² D. Lo,² P. Reshamwala.²
¹Department of Pharmacy, Emory University Hospital, Atlanta, GA; ²Emory Transplant Center, Emory University Hospital, Atlanta, GA.
Medication adherence post transplantation is vital. Upon discharge, abdominal transplant patients receive a medication list from the electronic medical record (EMR) and obtain a medication…
2018 American Transplant Congress
The Initial Hepatic Artery Reperfusion versus Initial Portal Reperfusion in Liver Transplantation: Where Do We Stand?
R. Shahbazov,¹ F. Azari,³ J. Alejo,² M. Talanian,² M. Fox,² K. Kennedy,² S. Kessel,² A. Nickkholgh,¹ D. Maluf,¹ S. Pelletier.¹
¹Surgery, University of Virginia Health System, Charlottesville, VA; ²School of Medicine, University of Virginia Health System, Charlottesville, VA; ³Surgery, University of Pennsylvania Medical Center, Philadelphia, PA.
Introduction: While initial portal vein reperfusion (PVRP) of a liver allograft is nearly standardized, limited data suggests initial hepatic arterial reperfusion (HARP) may improve hemodynamics…
2018 American Transplant Congress
Survival Advantage from Accepting a Circulatory Death Liver Transplant
J. Richards,¹ R. Taylor,² E. Allen,² A. Goh,¹ J. Neuberger,³ D. Collett,² G. Pettigrew.¹
¹Department of Surgery, University of Cambridge, Cambridge, United Kingdom; ²Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, United Kingdom; ³Department of Medicine, University of Birmingham, Birmingham, United Kingdom.
Background As liver failure increases in the UK, so does demand for liver transplantation. In response, UK donation after circulatory death (DCD) activity has approximately…
2018 American Transplant Congress
Utilization of Older Donor after Cardiac Death Allografts in Liver Transplantation: An Opportunity to Increase the Donor Pool
F. Paterno, K. Wima, T. Diwan, M. Cuffy, N. Anwar, E. Woodle, S. Shah.
Surgery, University of Cincinnati, Cincinnati, OH.
BackgroundDonors after cardiac death (DCD) liver allografts have been underutilized in liver transplantation especially in case of old donor age due to concerns of worse…
2018 American Transplant Congress
Tregs Expression Predicts Prognosis in Patients with Hepatocellular Carcinoma
A. Baquerizo,¹ V. Vavinskaya,² C. Frenette,¹ M. Nelson,¹ R. Schaffer,¹ J. Fisher,¹ L. Sher,³ B. Madani,¹ P. Pockros,¹ C. Marsh.¹
¹Surgery / Transplant, Scripps Green Hospital, La Jolla, CA; ²Pathology, UCSD, San Diego, CA; ³Surgery / Transplant, USC, Los Angeles, CA.
New therapeutic strategies are needed to improve the survival of patients with hepatocellular carcinoma (HCC), the third in overall global cancer-related mortality. T regulatory cells…