Articles tagged "Liver transplantation"

2018 American Transplant Congress
Rituximab Induction to Prevent the Recurrence of PSC after Liver Transplantation-The Lessons Learned from ABO-Incompatible Living Donor Liver Transplantation-
Y. Yamada,¹ K. Hoshino,¹ M. Shinoda,¹ H. Obara,¹ S. Uemoto,³ T. Kaido,³ H. Okajima,³ T. Yagi,⁴ T. Yoshizumi,⁵ Y. Inomata,⁶ T. Hibi,⁶ K. Kubota,⁷ T. Suzuki,⁸ Y. Kitagawa,¹ H. Egawa,² T. Kuroda.¹
¹Surgery, Keio University School of Medicine, Tokyo, Japan; ²Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan; ³Division of Hepato-Biliary-Pancreatic Surgery and Transplant Surgery, Kyoto University, Kyoto, Japan; ⁴Hepato-Biliary and Pancreatic Surgery, Okayama University, Okayama, Japan; ⁵Department of Surgery, Kyushu University, Fukuoka, Japan; ⁶Transplantation and Pediatric Surgery, Kumamoto University, Kumamoto, Japan; ⁷Department of Gastroenterological Surgery, Dokkyo Medical University, Tochigi, Japan; ⁸Department of Pediatric Surgery, Fujita Health University School of Medicine, Aichi, Japan.
Background: Multiple studies have failed to reveal an effective method for preventing the recurrence of primary sclerosing cholangitis (PSC) after liver transplantation (LTx). A national…
2018 American Transplant Congress
Surgical Categorization Improve Outcomes and Organ Utilization in Liver Transplant
H. Bohorquez,^1,2 H. Sharma,¹ D. Bruce,¹ A. Cohen,^1,2 C. Carmody,^1,2 J. Seal,¹ E. Bugeaud,¹ D. Sonnier,¹ A. Mathur,¹ D. Marroquin,¹ M. Voltz,¹ D. Lucia,¹ G. Loss.^1,2
¹Multi-Organ Transplant Institute, Ochsner Helath System, New Orleans, LA; ²School of Medicine, University of Queensland, New Orleans, LA.
Background: Liver transplant (LT) varies greatly in technical complexity due to factors such as prior surgery, obesity, and portal vein thrombosis (PVT). This must be…
2018 American Transplant Congress
Impact of Positive Donor Blood Cultures in Liver Transplant Recipients
D. Bley, D. Lo, G. Lyon III, R. Subramanian, S. Todd.
Emory University Hospital, Atlanta, GA.
The purpose of this study was to describe the bacteremia transmission rate of transplanting livers from donors with positive bacterial blood cultures into liver transplant…
2018 American Transplant Congress
Preoperative Antibiotics Treatment Decreases Endoplasmic Reticulum Stress and Protects Liver Transplant from Ischemia-Reperfusion Injury
T. Ito, F. Kaldas, K. Nakamura, S. Kageyama, A. Aziz, R. Busuttil, J. Kupiec-Weglinski.
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA.
Ischemia-reperfusion injury (IRI) represents a major risk factor of graft dysfunction in liver transplantation (LT). We have reported a critical role of endoplasmic reticulum (ER)…
2018 American Transplant Congress
Single-Dose Basiliximab Induction in Liver Transplant Recipients with Delayed CNI Initiation
D. Salerno,¹ N. Lange,¹ R. Rosenblatt,² C. Sammons,³ B. Fortune.²
¹Pharmacy, NewYork-Presbyterian Hospital, New York, NY; ²Medicine, Weill Cornell Medicine, New York, NY; ³Pharmacy, Hospital of the University of Pennsylvania, Philadelphia, PA.
Liver transplant recipients (LTR) with peri-operative renal injury benefit from a delayed CNI protocol using basiliximab (IL2RA) induction to reduce early CNI exposure. Existing literature…
2018 American Transplant Congress
Impact of Preserved Collateral Veins on Small-for-Size Grafts in Living Donor Liver Transplantation
B-.G. Na, E. Lee, S. Kim, S. Park.
Center for Liver Cancer, National Cancer Center Research Institute, Goyang, Republic of Korea.
Purpose: Graft size is a critical issue in living donor liver transplantation (LDLT). We hypothesized that too much portal flow could possibly be diverted into…
2018 American Transplant Congress
Opiate Use Trends after Liver Transplantation and the Factors Associated with Post-Transplant Opiate Dependence
M. Siddiqui,¹ R. Kaur,¹ S. Dhoop,² N. Sulejmani,¹ R. Salgia.¹
¹Henry Ford Hospital, Detroit, MI; ²Wayne State University SOM, Detroit, MI.
AimsOur study aims to determine predictive factors leading to post-liver transplant (LT) opioid dependence.MethodsA retrospective chart review was conducted including LT recipients from July 2013-June…
2018 American Transplant Congress
Pharmacological Defatting of Steatotic Human Livers Using a Novel Perfusion Solution during Normothermic Machine Perfusion
Y. Boteon,^1,2 J. Attard,^1,2 R. Laing,^1,2 A. Boteon,¹ R. Bhogal,¹ G. Reynold,² D. Neil,¹ H. Mergental,¹ D. Mirza,¹ S. Afford.²
¹National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; ²Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.
Introduction: Steatosis is the leading reason for donor livers discarding and contributes significantly to the worsening shortage of organs for transplantation. Steatotic livers commonly fail…
2018 American Transplant Congress
Clostridium Difficile Infection after Liver Transplant is Associated with Poor Long-Term Survival
A. Ahearn, P. Mahboub, N. Theodoropoulos, B. Movahedi, P. Martins, M. Campion, R. Nathan, A. Bozorgzadeh.
Division of Organ Transplantation, Umass Memorial Medical Center, Worcester, MA.
Background: Clostridium Difficile infection (CDI) is a growing problem in hospitalized patients and occurs in liver transplant recipients at a higher rate than non-transplant patients.…
2018 American Transplant Congress
Skeletons in the Closet? An Insight into Donor Liver Discards in the US
K. Halazun, A. Rana, G. Roll, P. Tabrizian, V. Agopian, B. Samstein, R. Brown, J. Emond.
Weill Cornell Medicine, NY, NY.
Background Liver discards are poorly investigated. Among these discarded livers are potentially useable grafts that could save the lives of many of the 2500-3000 who…