Articles tagged "Liver transplantation"

2018 American Transplant Congress
A Long-Term Experience with Expansion of Milan Criteria for Liver Transplant Recipients
S. Commander,¹ B. Shaw,¹ L. Washburn,² D. Yoeli,² A. Rana,² J. Goss.²
¹Duke University, Durham, NC; ²Baylor College of Medicine, Houston, TX.
Background: The Milan Criteria (MC) have historically determined eligibility for transplantation for hepatocellular carcinoma (HCC). The United Network for Organ Sharing (UNOS) Region 4 expanded…
2018 American Transplant Congress
De Novo Use of Extended Released Tacrolimus (Meltdose, Envasus^R)) after OLT – Does the Colonic Resorption Influences the Outcome?
T. Soliman, G. Györi, M. Hofmann, A. Salat, S. Rockenschaub, G. Berlakovich.
Department of Transplantation, Medical University of Vienna, Vienna, Austria.
Introduction: Immunosuppression after OLT has reached a quite high standard with an excellent evidence base. However, there is still a lack of data for the…
2018 American Transplant Congress
Pre Liver Transplant (LT) Prediction of Surgical Complexity by Recipient Risk Grading and Optimizing Outcomes: The Ochsner Experience
H. Sharma,¹ H. Bohorquez,^1,2 D. Bruce,¹ J. Seal,¹ A. Cohen,^1,2 E. Bugeaud,¹ I. Carmody,^1,2 D. Sonnier,¹ A. Mathur,¹ D. Marroquin,¹ M. Voltz,¹ L. DeGregorio,¹ G. Loss.^1,2
¹Multi-Organ Transplant Institute, Ochsner Health System, New Orleans, LA; ²School of Medicine, University of Queensland, New Orleans, LA.
Background: Ochsner Unit has been assigning the potential recipient with surgical complexity category since 2015 to preempt surgical risk .Aim: To review outcomes after the…
2018 American Transplant Congress
Mitigating Risk: Post-Exposure Prophylaxis in Liver Transplant Recipients from Donors with Potential Infectious Exposure
A. Nolan, D. Yarosh, S. Shaikh.
Department of Pharmacy, Medstar Georgetown University Hospital, Washington, DC.
Purpose: Increased risk organ donors are being more commonly utilized given organ shortages. However, there is a small risk of transmission of diseases such as…
2018 American Transplant Congress
The Role of Ex Vivo Normothermic Preservation in Minimizing Postreperfusion Syndrome in Liver Transplantation
A. Hassan, J. Cywinski, Q. Liu, D. Pezzati, D. Yang, L. Liu, G. Iuppa, K. Hashimoto, F. Aucejo, M. Fujiki, B. Eghtesad, S. Irefin, J. Fung, K. Abu-Elmagd, C. Miller, C. Quintini.
Transplant Surgery, Cleveland Clinic, Cleveland.
Background:Graft reperfusion holds a major challenge during liver transplantation. NMP may improve post-reperfusion hemodynamics, reduce vasopressor and blood product transfusion.Methods:15 patients with liver transplantation after…
2018 American Transplant Congress
Comparison of Outcome in Liver Transplant Patients with Renal Insufficiency and Intraoperative CVVH
J. Gosnell, M. Safwan, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai.
Transplant Institute, Henry Ford Health System, Detroit, MI.
Background: Intraoperative continuous veno-venous hemofiltration (CVVH) is an important tool to manage liver transplant (LT) patients with renal insufficiencies. Methods: All LT patients with renal…
2018 American Transplant Congress
Water-Jet Dissection for Donor Hepatectomy during Living Donor Liver Transplantation
K. Gotoh,¹ H. Eguchi,¹ Y. Iwagami,¹ D. Yamada,¹ T. Asaoka,¹ T. Noda,¹ K. Kawamoto,¹ S. Kobayashi,¹ K. Umeshita,² Y. Doki,¹ M. Mori.¹
¹Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan; ²Health Science, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.
Background The most important issue in living donor liver transplantation (LDLT) is donor safety. Although donor hepatectomy has evolved technically over the years, it is…
2018 American Transplant Congress
The AKI-Predict-Score: A New Prediction Model for Acute Kidney Injury after Liver Transplantation
M. Kalisvaart,¹ A. Schlegel,¹ I. Umbro,² K. Roberts,¹ D. Mirza,¹ T. Perera,¹ J. Isaac,¹ A. P. Mitterhofer,² J. de Jonge,³ P. Muiesan.¹
¹Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; ²Internal Medicine, Sapienza University, Rome, Italy; ³Surgery, Erasmus MC University Medical Center, Rotterdam, Netherlands.
BackgroundPostoperative acute kidney injury (AKI) is a frequent complication after liver transplantation and associated with impaired survival rates, chronic kidney disease and higher costs. Although…
2018 American Transplant Congress
mTOR Inhibition with Everolimus in De Novo Living Donor Liver Transplantation – 24-Months Results from the H2307 Pivotal Trial
L. Jeng,¹ S. Lee,¹ A. Soin,¹ S. Uemoto,¹ D. Maluf,¹ J. Emond,¹ M. Meier,² J. Kochuparampil,² C. Sips,² S. Kaneko,³ G. Levy.¹
¹H2307 Study Group, Taichung, Taiwan; ²Novartis Pharma AG, Basel, Switzerland; ³Novartis Pharma KK, Tokyo, Japan.
Purpose: Everolimus (EVR) with reduced-dose tacrolimus (rTAC) has been shown to be efficacious in preventing graft rejection and improving renal function in deceased-donor liver transplant…
2018 American Transplant Congress
Recipient HO-1 Deficiency Decreases Post-Transplant Graft HO-1 Expression and Exacerbates Liver Transplant Damage
S. Kageyama,¹ K. Nakamura,¹ T. Ito,¹ A. Aziz,¹ B. Ke,¹ R. Sossa,² E. Reed,² F. Kaldas,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Liver Transplantation, UCLA, Los Angeles, CA; ²Pathology, UCLA, Los Angeles, CA.
Many preclinical studies on protective functions of heme oxygenase-1 (HO-1; hsp32) in orthotopic liver transplantation (OLT) have encouraged application of HO-1 inducing regimens in clinical…