Articles tagged "Liver transplantation"

2018 American Transplant Congress
The AKI-Predict-Score: A New Prediction Model for Acute Kidney Injury after Liver Transplantation
M. Kalisvaart,¹ A. Schlegel,¹ I. Umbro,² K. Roberts,¹ D. Mirza,¹ T. Perera,¹ J. Isaac,¹ A. P. Mitterhofer,² J. de Jonge,³ P. Muiesan.¹
¹Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; ²Internal Medicine, Sapienza University, Rome, Italy; ³Surgery, Erasmus MC University Medical Center, Rotterdam, Netherlands.
BackgroundPostoperative acute kidney injury (AKI) is a frequent complication after liver transplantation and associated with impaired survival rates, chronic kidney disease and higher costs. Although…
2018 American Transplant Congress
Assessment of a Discharge Transplant Knowledge Quiz and Its Impact on Outcomes in Liver Transplant Recipients
H. Corbo, N. Patel, N. Pilch, C. Perez, J. Fleming, T. Harrison, J. Hardcopf, H. Meadows, B. O'Brien, J. McGillicuddy, P. Baliga, D. Taber.
Medical University of South Carolina, Charleston, SC.
The aim of this study is to determine if transplant quiz scores given prior to discharge were predictive of known patient risk factors and if…
2018 American Transplant Congress
Recombinant Relaxin Protects Liver Transplants from Ischemia-Reperfusion Damage via Hepatocyte Glucocorticoid Receptor: From Bench-to-Bedside
S. Kageyama,¹ K. Nakamura,¹ T. Ito,¹ A. Aziz,¹ B. Ke,¹ R. Sossa,² E. Reed,² F. Kaldas,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Division of Liver Transplantation, UCLA, Los Angeles, CA; ²Pathology, UCLA, Los Angeles, CA.
Hepatic ischemia-reperfusion injury (IRI) represents a major risk factor of early graft dysfunction and acute/chronic rejection as well as a key obstacle to expanding the…
2018 American Transplant Congress
Incidence of Acute Cellular Rejection in Liver Transplant Patients Receiving Direct Acting Antivirals for Hepatitis C Treatment
D. Bley,¹ L. Sagardia,¹ R. Ford,² S. Todd.¹
¹Pharmacy, Emory University Hospital, Atlanta, GA; ²School of Medicine, Emory University, Atlanta, GA.
Direct acting antivirals (DAAs) have been used for the treatment of hepatitis C (HCV) in liver transplant patients since early on after their approval, however…
2018 American Transplant Congress
Living Liver Donor Follow-Up: Fewer Than Half of Centers Meet Follow-Up Requirements in the US
A. Thomas, C. Holscher, A. Shaffer, J. Garonzik-Wang, A. Massie, D. Segev, M. Henderson.
JHU, Baltimore.
OPTN/UNOS began requiring 1-year living donor follow-up (LDF) for living liver donors (LLDs) in 2014. Compliance with a similar policy for living kidney donors was…
2018 American Transplant Congress
The Feasibility of Laparoscopic Living Donor Right Hepatectomy Compared to Open Surgery Including 100 Laparoscopic Cases
J. Rhu, G. Choi, J. Kim, J. Joh, C. Kwon, S. Kim.
Department of Surgery, Samsung Medical Center, Seoul, Republic of Korea.
Background: We designed this study to analyze the feasibility of laparoscopic living donor hepatectomy by comparing to open living donor hepatectomy.Methods : Living donors who…
2018 American Transplant Congress
Histone Deacetylase-6 Inhibition Mitigates Liver Ischemia-Reperfusion Injury and Acetaminophen Toxicity in Mice
S. Concors,¹ D. Murken,¹ D. Aufhauser,¹ Z. Wang,¹ G. Ge,¹ T. Bhatti,⁴ W. Hancock,^3,4 M. Levine.^1,2
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Surgery, Children's Hospital of Philadelphia, Philadelphia, PA; ³Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA; ⁴Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
Introduction: Ischemia/reperfusion injury (IRI) leads to poor outcomes and early graft loss in liver transplantation. Understanding the mechanisms of liver IRI may aid in prevention…
2018 American Transplant Congress
Isolated Right Hepatic Vein (RHV) Obstruction after Piggyback Liver Transplantation, an Infrahepatic Terminolateral Cavo-Cavostomy as a Rescue Technique to Save the Graft
K. Pineda-Solis, C. Florez-Zorrilla, A. Sanchez-Cedillo, L. Ladrón de Guevara-Cetrina.
Transplant Unit, National Medical Center "20 de Noviembre", Mexico City, Mexico.
Background: The “piggyback” technique for liver transplantation (LT) has gained acceptance around the world. However, outflow problems are more common than the classic technique.Material and…
2018 American Transplant Congress
Development and Validation of Nomogram to Predict Primary Non Function in Liver Transplant Recipients Using Donation after Cardiac Death Donor Graft
Z. Guo, J. Zeng, Q. Zhao, B. Chen, Z. Zhang, L. Wang, X. He.
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Primary non function(PNF) is a severe complication after liver transplantation which causes recipient death or re-transplantation in a short term. PNF occurs more common in…
2018 American Transplant Congress
Association between Everolimus Trough Levels, Onset of Related Adverse Events, and Treatment Discontinuation after Liver Transplantation: 24-Month Results from the H2304 Study
J. Fung,¹ F. Saliba,¹ H. Schlitt,¹ G. Junge,² K. McCague,³ D. Patel,³ M. Charlton.¹
¹H2304 Study Group, Chicago; ²Novartis Pharma AG, Basel, Switzerland; ³Novartis Pharmaceuticals Corporation, East Hanover.
Purpose: Evaluation of mammalian target of rapamycin inhibitor (mTORi)-related adverse events (AEs) and drug trough levels (C0) at onset may aid their management in liver…