Articles tagged "Liver transplantation"

2018 American Transplant Congress
Prediction of Hepatocellular Carcinoma Recurrence Following Liver Transplantation Using Combined Differential Gene Expression, Copy Number Variation and Somatic Mutation Analysis
A. Humar,¹ P. Liu,² J. Luo,³ M. Nalesnik,³ A. Singhi,³ G. Tseng,² G. Michalopoulos.³
¹Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA; ²Biostatistics, University of Pittsburgh, Pittsburgh, PA; ³Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.
Liver allocation for transplant candidates with hepatocellular carcinoma is limited by OPTN policy to patients whose tumors remain within size limits defined by Milan criteria.…
2018 American Transplant Congress
Sustained Improvement in Patient Reported Outcomes 10 Years after Liver Transplantation by Protocol Longitudinal Assessment of Health Related Quality of Life
S. Elwir,¹ A. Warren,¹ G. Saracino,¹ S. Asrani,¹ T. Elliott,² G. Klintmalm.¹
¹Baylor University Medical Center, Dallas, TX; ²Department of Educational Psychology, Texas A&M University, College Station, TX.
Purpose: Data on patient (pt) reported outcomes, especially beyond the first year after liver transplantation (LT) are scarce. We examined changes in health related quality…
2018 American Transplant Congress
Ethnic and Age Disparities in Outcomes among Liver Transplant Waitlist Candidates
M. Mustian,¹ S. Gray,¹ B. Shelton,¹ R. Reed,¹ P. MacLennan,¹ J. White,¹ D. Eckhoff,¹ R. Allman,² J. Locke.¹
¹University of Alabama at Birmingham, Birmingham; ²Department of Veterans Affairs, Washington DC.
Background: Despite the increasing prevalence of end-stage liver disease (ESLD) in older adults, there is no consensus to determine suitability for liver transplantation (LT) in…
2018 American Transplant Congress
Impact of Early Corticosteroid Treatment in Patients with Indeterminate Acute Severe Hepatitis
E. Mohr,¹ R. Sucher,² T. Müller,³ T. Kaiser,⁴ T. Berg.¹
¹Hepatology, University Clinic Leipzig, Leipzig, Germany; ²Transplant Surgery, University Clinic Leipzig, Leipzig, Germany; ³Hepatology, Charite, Berliin, Germany; ⁴Laboratory Diagnostics, University Clinic Leipzig, Leipzig, Germany.
Background and Aims: Discrimination of acute severe autoimmune hepatitis AIH and drug induced liver injury in patients with indeterminate acute severe Hepatitis is challenging. Early…
2018 American Transplant Congress
Impact of Fluconazole Prophylaxis on Fungal Infections in Liver Transplant Recipients
K. Roach,¹ S. Todd,² M. Lyon,² R. Subramanian.²
¹Lahey Hospital and Medical Center, Burlington, MA; ²Emory University Hospital, Atlanta, GA.
The purpose of this study was to assess if utilizing fluconazole for prophylaxis of invasive fungal infections (IFIs) in high risk liver transplant recipients is…
2018 American Transplant Congress
Serum Beta-(1,3)-D-Glucan as a Case-Finding Tool during an Outbreak of Pneumocystitis jirovecii Pneumonia in Abdominal Transplant Patients
J. Mittal, J. Mogollon, K. Cowman, P. Nori, V. Muggia, G. Minamoto, Y. Puius.
Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY.
Background: Pneumocystis jirovecii pneumonia(PJP) in solid organ transplant (SOT) recipients carries significant morbidity and mortality. There is mounting evidence for ongoing risk of PJP in…
2018 American Transplant Congress
Modified Protocol for ABO-Incompatible Living Donor Liver Transplantation with Rituximab and Intravenous Immunoglobulin without Plasma Exchange
B-.G. Na, E. Lee, S. Kim, S. Park.
Center for Liver Cancer, National Cancer Center, Il-san Donggu, Goyang, Republic of Korea.
Purpose: Since a variety of desensitization strategies including rituximab, intravenous immunoglobulin (IVIG), and plasma exchange (PE) have been introduced, the survival and outcomes of recipients…
2018 American Transplant Congress
Exosomes from Umbilical Cord-Derived Mesenchymal Stem Cells on Hepatocytes Proliferation after Small-for-Size Liver Transplantation via RHO/ROCK Pathway
L. Chen, J. Zheng, J. Cai, J. Yao, K. Zeng, Y. Zhang, Y. Yang.
Department of Liver Transplantation, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Exosomes from umbilical cords-derived mesenchymal stem cells (UC-MSCs-Ex) have been recognized as their ability to promote tissue regeneration in many animal models. However, the in…
2018 American Transplant Congress
The Transplant-Death Index: A Novel Method to Identify Disenfranchised Liver Transplant Waitlist Candidates
M. Kueht, J. Goss, N. Galvan, A. Rana.
Surgery, Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX.
The transplant field is seeing a shift in outcome priorities from just 1-year survival to include waitlist metrics such as the transplant rate. Identifying disenfranchised…
2018 American Transplant Congress
Livers from Donation after Circulatory Death Donors Can Be Safely Used for Retransplantation
O. van Leeuwen,¹ M. van Reeven,² J. Erdmann,³ H. Metselaar,⁴ A. van den Berg,⁵ B. van Hoek,⁶ W. Polak,² R. Porte.¹
¹Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; ²Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands; ³Department of Surgery, Leiden University Medical Center, Leiden, Netherlands; ⁴Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, Netherlands; ⁵Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, Netherlands; ⁶Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands.
Introduction: After donation after circulatory death (DCD) liver transplantation (LT), non-anastomotic biliary strictures (NAS) and early allograft dysfunction (EAD) are more frequently observed than after…