Articles tagged "Liver transplantation"

2018 American Transplant Congress
Liver Transplant Patients with MELD>50 at Listing Have Poor Waitlist Outcomes and Similar Post Transplant Survival to Status 1A Patients
M. Safwan, R. Schilke, U. Nwagu, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai.
Henry Ford Health System, Detroit, MI.
Background: Allocation of liver allografts is prioritized to Status 1A patients over end-stage liver disease patients. We aimed to analyze waitlist and transplant outcomes of…
2018 American Transplant Congress
Donor and Procedural Variability in DCD Liver Transplant: Is It Time to Come to a Consensus?
L. Ruffolo, M. Balceniuk, R. Hernandez Alejandro.
Department of Surgery, University of Rochester Medical Center on Behalf of the IDOL Consortium, Rochester, NY.
Background:Donation after cardiocirculatory death liver transplantation (DCD LT) has re-emerged in part because of insufficient grafts for patients on waiting lists. Unfortunately, DCD LT has…
2018 American Transplant Congress
A Review of Pediatric Drug Development Programs and FDA Labeling for Immunosuppressive Drugs in Organ Transplant Patients
G. Burckart,¹ M. Cavaillé-Coll,² A. Duong,³ L. Hothem,⁴ R. Albrecht.²
¹Office of Clinical Pharmacology, Office of Translational Science, CDER, US Food and Drug Administration, Silver Spring, MD; ²Division of Transplant and Opthalmology Products, Office of New Drugs, CDER, US Food and Drug Administration, Silver Spring, MD; ³Tauro University, New York, NY; ⁴University of North Carolina, Chapel Hill, NC.
The development of drugs for organ transplantation spanned the time before and after pediatric regulatory requirements under the Best Pharmaceuticals for Children Act (BPCA) and…
2018 American Transplant Congress
Donor-to-Recipient Weight Ratio is Significantly Associated with Hepatic Artery Thrombosis Following Pediatric Whole Liver Transplantation
S. Kim, G. Ramos-Gonzalez, Z. Labib, H. Kim, K. Vakili.
Surgery, Boston Children's Hospital, Boston, MA.
Background: Hepatic artery thrombosis (HAT) following pediatric liver transplantation is associated with increased morbidity and risk of graft failure. In our clinical practice, we have…
2018 American Transplant Congress
Single Center Experience of HLA-Related Donor Specific Antibody in Living Donor Liver Transplantation
H. Egawa,¹ Y. Kotera,¹ A. Ohmori,¹ S. Yamashita,¹ T. Kato,¹ S. Nemoto,¹ T. Ishizuka,² M. Yamamoto.¹
¹Surgery, Tokyo Women's Medical University, Tokyo, Japan; ²Clinical Laboratory, Tokyo Women's Medical University, Tokyo, Japan.
Although impact of donor specific antibody in liver transplantation has been recognized, significance of desensitization is not established yet. Our aim is to share our…
2018 American Transplant Congress
Hospitalization and Life Support before Liver Transplantation – Easily Available Predictors for Post-Transplant Patient Survival
L. Wiering, P. Ritschl, M. Hippler-Benscheidt, F. Aigner, M. Biebl, D. Eurich, M. Schmelzle, I. Sauer, K. Kotsch, J. Pratschke, R. Öllinger.
Chirurgische Klinik Campus Charité Mitte / Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Berlin, Germany.
IntroductionCurrently liver allocation -in contrast to allocation of other organs- is based on urgency in many countries and survival benefit is not included. Aim of…
2018 American Transplant Congress
Identifying Differences in Antimicrobial Resistance with a Liver Transplant Antibiogram
J. Rago, M. Crotty, E. Milas, E. Dominguez.
Methodist Dallas Medical Center, Dallas.
Regulatory requirements for antimicrobial stewardship pose a unique challenge in special populations including transplant recipients. Infection following liver transplant can adversely impact patient outcomes. Moreover,…
2018 American Transplant Congress
High Dose Tissue Plasminogen Activator Flush during Donation-after-Cardiac-Death (DCD) Liver Procurements Offers Optimal Outcomes
J. Torabi,² J. Graham,^1,2 S. Bellmare,^1,2 M. Kinkhabwala,^1,2 J. Rocca.^1,2
¹Montefiore Center for Transplantation, Montefiore Medical Center, Bronx, NY; ²Albert Einstein College of Medicine, Bronx, NY.
BackgroundEfforts to expand the donor pool have resulted in increased utilization of donation-after-cardiac-death (DCD) liver donors. Here we report on our experience using high dose…
2018 American Transplant Congress
Assesment of a Novel Chronic Kidney Disease Educational and Goal Setting Tool among Liver Transplant Recipients
R. Leek,¹ J. Park,¹ C. Koerschner,² J. Mawby,³ J. Wright Nunes,⁴ C. Sonnenday,³ P. Sharma.²
¹College of Pharmacy, University of Michigan, Ann Arbor; ²Gastroenterology and Hepatology, University of Michigan, Ann Arbor; ³Transplantation Surgery, University of Michigan, Ann Arbor; ⁴Nephrology, University of Michigan, Ann Arbor.
Background: Stage 4-5 chronic kidney disease(CKD) among liver transplant(LT) recipients is common and associated with diminished patient and graft outcomes. Our previous study showed that…
2018 American Transplant Congress
Renal and Bone Safety in Post Liver Transplant Patients with Chronic Kidney Disease Receiving Tenofovir Alafenamide for HBV Prophylaxis
E. Gane,¹ B. George,¹ S. Munn,¹ H. Wang,² V. Suri,² A. Gaggar.²
¹Auckland City Hospital, Auckland, New Zealand; ²Gilead Sciences, Foster City, CA.
Background and Aims: Chronic Hepatitis B (CHB) remains a leading indication for orthotopic liver transplantation (OLT) globally. Common complications following OLT include renal dysfunction secondary…