Articles tagged "Liver transplantation"

2018 American Transplant Congress
Ischemia Reperfusion Injury in Liver Transplantation is Associated with Acute Kidney Injury: Role of Inflammatory Mediators
P. Mihaylov,^1,2 P. Li,¹ J. Skill,¹ L. Timsina,¹ J. Fridell,¹ B. Ekser,¹ R. Mangus,¹ C. Kubal.¹
¹Surgery, Indiana University, Indianapolis; ²Surgery, University of Pavia, Pavia, Italy.
Background: The impact of liver allograft ischemia/reperfusion injury (IRI) on native renal function remains to be characterized. We hypothesized that elevated levels of circulating inflammatory…
2018 American Transplant Congress
Long-Term Follow-Up of Patients with Primary Sclerosing Cholangitis Undergoing Liver Transplantation with Duct-to-Duct Biliary Reconstruction
L. Coromina Hernandez, B. Eghtesad, T. Diago, K. Hashimoto, M. Fujiki, C. Quintini, F. Aucejo, G. Iuppa, A. Hassan, N. Menon, C. Miller.
Transplant Surgery, Cleveland Clinic, Cleveland, OH.
Background:Reconstruction of biliary drainage after liver transplantation (LTx) in patients with primary sclerosing cholangitis (PSC) has been a matter of controversy. Over the recent years,…
2018 American Transplant Congress
Geographic Disparity in Access to Deceased-Donor Liver Transplantation for Pediatric Candidates
M. Bowring,¹ D. Mogul,¹ D. Segev,¹ S. Gentry.^1,2
¹JHU, Baltimore; ²US Naval Academy, Annapolis.
Geographic disparity in access to deceased-donor liver transplantation (DDLT) is largely uncharacterized for pediatric candidates. We investigated geographic disparity in DDLT rates across Donation Service…
2018 American Transplant Congress
Liver Transplantation for Patients with Hepatocellular Carcinoma Presenting beyond Milan Criteria: Analysis of 789 Patients from the US Multicenter HCC Transplant Consortium
V. Agopian, United States Multicenter HCC Transplant Consortium.
UCLA, LA.
Objective: OPTN has recently approved MELD prioritization for HCC patients beyond Milan Criteria (MC) who are downstaged (DS) with locoregional therapy (LRT) prior to liver…
2018 American Transplant Congress
Results of LITMUS (NCT 02541916): The Liver Immune Tolerance Bio Marker Utilization Study
A. Chruscinski,¹ V. Rojas-Luengas,¹ A. Issacher,¹ J. Luo,⁴ H. Yowanto,⁴ N. Selzner,¹ L. Lilly,¹ R. Smith,¹ E. Renner,¹ J. Zhang,¹ D. Grant,¹ O. Adeyi,¹ H. Atkins,² P. Juni,³ G. Levy.¹
¹Multi Organ Transplant Program, University Health Network, Toronto, ON, Canada; ²The Ottawa Hospital Blood and Marrow Transplant Program, The Ottawa Hospital, Ottawa, ON, Canada; ³Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada; ⁴SCIEX, Brea, CA.
Background: Previously we reported a novel biomarker gene set for the identification of tolerance in murine models of rapamycin-induced cardiac tolerance and spontaneous hepatic tolerance.…
2018 American Transplant Congress
Can Delayed Abdominal Fascia Closure Modify the Short Term Outcome after Adult Liver Transplantation?
I. Vella,¹ M. Pellicciaro,¹ G. Ciancio,² T. Manzia,¹ R. Angelico,³ J. Gaynor,² G. Iaria,¹ G. Tisone,¹ R. Vianna.²
¹Transplant Unit, University of Rome "Tor Vergata", Rome, Italy; ²Miami Transplant Institute, University of Miami Miller School of Medicine, Miami; ³Ospedale Pediatrico Bambino Ges[ugrave], Rome, Italy.
BackgroundThe abdominal fascia at the end of adult liver transplantation could often represents a dangerous procedure, complicated by graft size mismatch and post reperfusion hepatic…
2018 American Transplant Congress
Outcomes of Livers Allocated to High UNOS Match Sequence Number Recipients at a High Volume Transplant Center
M. Park, L. De Gregorio, H. Bohorquez, D. Bruce, E. Bugeaud, I. Carmody, A. Cohen, A. Mathur, D. Sonnier, J. Seal, G. Loss.
Ochsner Medical Center, New Orleans, LA.
IntroductionImproved utilization of expanded criteria donor (ECD) allografts offers an opportunity to expand the donor pool, reduce wait-times and waitlist mortality. We analyzed outcomes at…
2018 American Transplant Congress
Most Pediatric Transplant Centers Are Underperforming and in Proximity to Higher Volume Centers
T. Nichols, A. Rana, J. Goss.
Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.
Purpose. Many research studies have shown that low case volume has been associated with worse survival outcomes in each type of pediatric solid organ transplant.…
2018 American Transplant Congress
Impact of Mammalian Target of Rapamycin Inhibitors on Hepatocellular Carcinoma Recurrence after Liver Transplant
N. Hendon,¹ D. Salerno,¹ C. Sammons,¹ K. Halazun.²
¹Pharmacy, NewYork-Presbyterian Hospital, New York, NY; ²Surgery, Weill Cornell Medical College, New York, NY.
Despite limited benefit to patients within Milan criteria on explant, mTORi are routinely utilized for prevention of hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT).…
2018 American Transplant Congress
Patient-Centered Outcomes after Liver Transplantation: A Qualitative Study
G. Lee, J. Obayemi, E. Rubin.
Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA; Medicine, Massachusetts General Hospital, Boston, MA.
Introduction: Outcomes after liver transplantation are most commonly reported by medical professionals as rates of graft failure, episodes of acute rejection, length of hospital stay,…