ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2022 American Transplant Congress

    Type 1 Innate Lymphoid Cells Alleviate Acute Liver Injury Following Transplantation via Interferon-γ Mediated Pathway

    H. Kojima, K. Kadono, H. Hirao, K. J. Dery, J. Kupiec-Weglinski, Y. Zhai

    Dumont-UCLA Transplant Center, Los Angeles, CA

    *Purpose: Innate lymphoid cells (ILCs), a heterogeneous population of non-B non-T lymphocytes, have been found in recent years to plays key regulatory roles in tissue…
  • 2022 American Transplant Congress

    The Impact of Yttium-90 Radioembolization on T Cell Phenotypes in Bridged to Transplant Hepatocellular Carcinoma Patients

    K. Nunez, T. Sandow, P. Thevenot, A. Cohen

    Ochsner Health System, New Orleans, LA

    *Purpose: Response to locoregional therapy (LRT) in hepatocellular carcinoma (HCC) impacts both progression-free survival (PFS) and bridge to transplant success. Yttrium-90 (Y90) is an effective…
  • 2022 American Transplant Congress

    An International Multi-Institutional Comparison of Liver Transplantation for Hepatocellular Carcinoma: United States, United Kingdom, and Canada

    T. Ivanics1, D. Wallace2, M. P. Claasen3, M. Patel4, W. Jassem5, K. Menon5, A. Suddle5, N. Heaton5, N. Mehta6, J. van der Meulen2, G. Sapisochin3

    1University of Toronto - University Health Network, Toronto, ON, Canada, 2Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom, 3Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada, 4Division of Surgical Transplantation, University of Texas Southwestern Medical Center, Dallas, TX, 5Institute of Liver Studies, King's College Hospital, London, United Kingdom, 6UCSF, San Francisco, CA

    *Purpose: Hepatocellular carcinoma (HCC) has become a leading indication for liver transplantation (LT) globally. Given the scarcity of organs, the general consensus has been that…
  • 2022 American Transplant Congress

    The Feasibility of Changing HCC MELD Exception Criteria to an Exclusive DCD-Only Option: A Strategy to Increase DCD Utilization

    G. J. McKenna, P. Schultz, M. Finotti, M. Rosenzweig, A. Gupta, S. H. Lee, A. Wall, E. Martinez, J. Bayer, H. Fernandez, N. Onaca, R. Ruiz, G. Testa

    Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX

    *Purpose: Outcomes of DCD liver transplantation is comparable to DBD but routine utilization of DCD liver grafts is surprisingly uneven in the US. A more…
  • 2022 American Transplant Congress

    Pre-Transplant Frailty Predicts Infection After Liver Transplant in a Multi-Center Study of Older Adults

    M. Malinis1, M. Abidi2, E. Benamu2, N. Jakharia3, N. Law4, R. Sigler4, R. Nog5, S. Olivier5, S. Taimur6, N. Theodoropoulos7, J. Schaenman8

    1Yale SOM, New Haven, CT, 2Univ of CO, Aurora, CO, 3Stanford, Palo, Alto, CA, 4UCSD, San Diego, CA, 5Westchester Med Ctr, Westchester, NY, 6Mount Sinai SOM, New York, NY, 7Univ of MA, Worcester, MA, 8UCLA, Los Angeles, CA

    *Purpose: Frailty is a complex multi-system characterization of reduced physiologic reserve and functional decline in older adults. At the time of transplant, frailty has been…
  • 2022 American Transplant Congress

    Clinical Stratification of Pediatric Liver Transplant Recipients 4-5 Years Post-Transplant: 1St Step Towards Personalized Management

    W. Dixon1, E. R. Perito1, M. Tavakol1, J. Bucuvalas2, S. Feng1

    1University of California, San Francisco, San Francisco, CA, 2Mount Sinai Kravis Children's Hospital and Recanati/Miller Transplantation Institute, Mount Sinai Health System, New York, NY

    *Purpose: Recent surveillance biopsy studies strongly associate high normal ALT (>35U/L) with inflammatory histopathology and low normal ALT (15yrs (n=13; p=0.0006), chronic rejection (CR) diagnosis…
  • 2022 American Transplant Congress

    Significant Improvements, but Consistent Disparities in Survival for African Americans After Liver Transplantation

    S. S. Keeling

    Baylor College of Medicine, Houston, TX

    *Purpose: Despite improvements in survival for all races in the past twenty years, African American patients have worse liver transplant outcomes after undergoing orthotopic liver…
  • 2022 American Transplant Congress

    Assessing Safety of Using ECMO-Supported Donors in Abdominal Transplantation

    P. J. Altshuler1, A. P. Shah1, J. M. Glorioso1, W. R. Maley1, A. M. Frank1, C. B. Ramirez1, H. Dang1, S. West2, R. Hasz, Jr.2, A. S. Bodzin1

    1Department of Surgery, Thomas Jefferson University, Philadelphia, PA, 2Gift Of Life Donor Program, Philadelphia, PA

    *Purpose: Organ donors supported by extracorporeal membrane oxygenation (ECMO) are historically considered high-risk and are judiciously utilized. Here we explore the safety of using organs…
  • 2022 American Transplant Congress

    Long-Term Follow Up of Solid Organ Transplantation Using Hepatitis C Virus Positive Donor for Hepatitis C Virus Negative Recipients

    H. Sogawa1, I. Lee2, K. Okumura3, R. Bodin4, D. C. Wolf4, B. Partiula4, A. Dhand4, M. Kai5, S. Ohira5, R. Misawa1, G. Veillette6, D. John1, S. Nishida7, T. Diflo6

    1Division of Intra-abdominal Organ Transplant, Department of Surgery, Westchester Medical Center/ New York Medical College, Valhalla, NY, 2Department of Surgery, Westchester Medical Center/ New York Medical College, Valhalla, NY, 3Surgery, Westchester Medical Center/New York Medical College, Valhalla, NY, 4Department of Medicine, Westchester Medical Center/ New York Medical College, Valhalla, NY, 5Cardiothoracic Surgery, Westchester Medical Center/ New York Medical College, Valhalla, NY, 6Westchester Medical Center, Valhalla, NY, 7Westchester Medical Center/ New York Medical College, Valhalla, NY

    *Purpose: To determine the effects of transplanting an HCV + solid organ to an uninfected patient who is on the transplant waiting list. Outcomes include…
  • 2022 American Transplant Congress

    Efficacy and Safety of Delayed, Low-Dose Valganciclovir in High-Risk Cytomegalovirus Liver Transplant Recipients

    S. Anders1, A. Freeman1, L. Hutchinson1, U. Kaszubski1, M. Janusek1, A. Hooter2, D. Raymond2, C. Nguyen2

    1Ochsner Medical Center, New Orleans, LA, 2Xavier University, New Orleans, LA

    *Purpose: The goal of this study was to compare the safety and efficacy of a delayed valganciclovir (VGCV) dosing protocol for cytomegalovirus (CMV) prophylaxis in…
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