Articles tagged "Liver grafts"

2018 American Transplant Congress
Outcomes of Liver Transplant in Sequential Eras in Patients with Polycystic Liver Disease at Various Stages of Disease
C. Desai,¹ J. Shurney,¹ P. Serrano Rodriguez,¹ A. Barritt,¹ D. Gerber,¹ A. Gruessner.²
¹University of North Carolina, Chapel Hill, NC; ²SUNY Downstate Medical Center, Brooklyn, NY.
Patients with polycystic liver disease (PLD) receive liver transplants at various time points in their disease process. Some patients receive liver transplant alone (L), some…
2018 American Transplant Congress
Impact of Donor Hepatectomy Time during Organ Procurement in Donation after Circulatory Death Liver Transplantation; The United Kingdom Experience
S. Farid, A. Magdy, D. Vijayanand, V. Upasani, S. Willis, A. Barlow, H. Ernest, A. Niaz.
St James University Hospital, Leeds, United Kingdom.
IntroductionNo data exists to evaluate the impact of hepatectomy time (HT) during donation after cardiac death (DCD) procurement on short and long-term outcomes following liver…
2018 American Transplant Congress
Daptomycin Minimum Inhibitory Concentration (MIC) of Vancomycin Resistant Enterococcal (VRE) Blood Isolates Correlates with Allograft Failure in Orthotopic Liver Transplant (OLT) Recipients
R. Lee,¹ G. Haidar,² J. Lewis,³ S. Arif,⁴ J. Hand,⁵ E. Holaday,⁶ H. Clauss,⁶ J. Goldman,⁷ A. Nellore.¹
¹University of Alabama at Birmingham, Birmingham, AL; ²University of Pittsburgh Medical Center, Birmingham, AL; ³University of Virginia, Charlottesville, VA; ⁴Duke University, Durham, NC; ⁵Oschner Medical Center, New Orleans, LA; ⁶Department of Internal Medicine, Temple University, Philadelphia, PA; ⁷Temple University, Philadelphia, PA; ⁸Swedish Medical Center, Seattle, WA.
Background: Enterococci are one of the leading causes of nosocomial infection in after OLT. Unfortunately, treatment options for enterococci that are resistant to first-line agents…
2018 American Transplant Congress
LDLT for High MELD Recipients: A Single Center Experience
S. Ganesh, M. Molinari, T. Amit, H. Christopher, H. Abhinav.
Surgery, University of Pittsburgh, Pittsburgh, PA.
Objectives: Living donor liver transplantation (LDLT) is underutilized in high MELD patients. Our aim was to assess the impact of high MELD score on short-term…
2018 American Transplant Congress
Persistent Progressive Acute Kidney Injury and Graft Failure Post Liver Transplantation
T. Hussaini,^1,4 N. Partovi,^1,4 E. Yoshida,^2,4 S. Erb,^2,4 C. Scudammore,^3,4 S. Chung,^3,4 V. Marquez.^2,4
¹Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada; ²Faculty of Medicine, Division of Gastroenterology, University of British Columbia, Vancouver, BC, Canada; ³Faculty of Medicine, Division of Surgery, University of British Columbia, Vancouver, BC, Canada; ⁴Liver Transplant Program, Vancouver General Hospital, Vancouver, BC, Canada.
Background:Acute kidney injury (AKI) in the setting of liver transplantation (LT) is a common and multifaceted complication. Recently, with the widespread adaptation of Acute Kidney…
2018 American Transplant Congress
Assessment of Hepatic Ischemia-Reperfusion Injuries by NRF2-Dependent Transcriptional Activities of Bile Transporters in Rats
J. Kim,¹ A. Martin,¹ J. Yee,¹ L. Fojut,¹ A. Geurts,² K. Oshima,³ M. Zimmerman,¹ J. Hong.¹
¹Surgery, Medical College of Wisconsin, Milwaukee, WI; ²Physiology, Medical College of Wisconsin, Milwaukee, WI; ³Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.
Background: The effect of hepatic ischemia and reperfusion injury (IRI) on bile transporter (BT) gene expression and the role of Nrf2 in BT regulation during…
2018 American Transplant Congress
Living Donor Liver Transplant (LDLT) at a Single Center- Intraoperative Technical Modifications and Optimization of Flow Dynamics to Improve Outcomes
A. Humar, S. Ganesh, A. Tevar, M. Molinari, C. Hughes.
Surgery, University of Pittsburgh, Pittsburgh.
Objectives: While LDLT represents the dominant method of LTx in the East, it remains an underutilized procedure in the US, accounting for <5% of all…
2018 American Transplant Congress
Involvement of Aldehyde Dehydrogenase 2 (ALDH2) in Fatty Liver Graft Protection Mechanisms against Cold Ischemic Injury
A. Panisello-Rosello,¹ A. Lopez,² C. Castro,² S. Bellogi,¹ E. Folch-Puy,¹ A. Rolo,³ C. Palmeira,³ R. Adam, J. Roselló-Catafau.
¹Experimental Pathology, Instituto de Investigaciones Biomédicas de Barcelona, Barcelona, Catalonia, Spain; ²INSERM U935, Hôpital Paul Brousse, Paris, France; ³Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Aldehyde dehydogenase (ALDH2) is a mitochondrial enzyme that recently has been involved in the cardioprotection against ischemia injury. No data are reported on the potential…
2018 American Transplant Congress
The Safety and Efficacy of Splenic Artery Ligation in Living Donor Liver Transplant Recipients
Y. Gunay, S. Ganesh, M. Molinari, A. Tevar, C. Hughes, A. Humar.
Surgery, University of Pittsburgh, Pittsburgh.
Introduction: Portal hypertension in recipients undergoing living donor liver transplant (LDLT) is thought to be one of the main causes of posttransplant graft dysfunction. In…
2018 American Transplant Congress
The Initial Hepatic Artery Reperfusion versus Initial Portal Reperfusion in Liver Transplantation: Where Do We Stand?
R. Shahbazov,¹ F. Azari,³ J. Alejo,² M. Talanian,² M. Fox,² K. Kennedy,² S. Kessel,² A. Nickkholgh,¹ D. Maluf,¹ S. Pelletier.¹
¹Surgery, University of Virginia Health System, Charlottesville, VA; ²School of Medicine, University of Virginia Health System, Charlottesville, VA; ³Surgery, University of Pennsylvania Medical Center, Philadelphia, PA.
Introduction: While initial portal vein reperfusion (PVRP) of a liver allograft is nearly standardized, limited data suggests initial hepatic arterial reperfusion (HARP) may improve hemodynamics…