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Articles tagged "Liver failure"

  • 2016 American Transplant Congress

    Cytokine Storm in Acute Post-Hepatectmy Phase Associates with Liver Injury and Impaired Liver Regeneration.

    Y. Xu,1,2 N. Navarro-Alvarez,1 J. Dong,2 J. Markmann,1 H. Yeh.1

    1Transplantation Division, Massachusetts General Hospital, Boston, MA; 2Department of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing, China.

    Background Posthepatectomy liver failure and its transplant counterpart, small-for-size syndrome, remain poorly understood. Large increases in IL-6 are associated with poor allograft function and IL-6…
  • 2016 American Transplant Congress

    Outcomes Following Inguinal Hernia Repair in Patients with End Stage Liver Disease.

    N. Dagher, S. DiBrito, I. Olorundare, C. Landazabal, D. Segev.

    Transplant Surgery, Johns Hopkins Hospital, Baltimore.

    Increased abdominal pressure and girth from ascites puts patients with end stage liver disease (ESLD) at high risk for inguinal hernia as well as challenges…
  • 2016 American Transplant Congress

    Acute-on-Chronic Liver Failure Admissions Cost 3 Times More Than Non-ACLF Related Admissions.

    S. Leffingwell, J. O'Leary, S. Asrani.

    Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX.

    Background: Acute-on-chronic liver failure (ACLF) is associated with significant resource utilization. However, the relative charges associated with ACLF are not established.Methods: We examined cirrhotics admitted…
  • 2015 American Transplant Congress

    Validation of the Model for End-Stage Liver Disease Score Criteria in Liver Transplantation for Acute Flare Up of Hepatitis B in Non-Cirrhotic Liver

    W.-C. Lee,1 T.-J. Wu,1 C.-F. Lee,1 R.-S. Soong,1 C.-H. Cheng,1 H.-S. Chou,1 T.-H. Wu,1 K.-M. Chan,1 Y.-C. Wang,1 C.-S. Lee.2

    1Liver and Transplantation Surgery, Chang-Gung Memorial Hospital, Chang-Gung University College of Medicine, Taoyuan, Taiwan; 2Hepatology, Chang-Gung Memorial Hospital, Chang-Gung University College of Medicine, Taoyuan, Taiwan.

    Background: Decision of necessity of urgent liver transplantation for acute flare up of hepatitis B in the patients without cirrhosis is difficult. The MELD score…
  • 2015 American Transplant Congress

    Functional Status Predicts Mortality After Liver Transplant

    N. Dolgin,1,2 P. Martins,1 F. Anderson,1,2 A. Bozorgzadeh.1

    1Surgery, UMass Memorial Medical Center, Worcester, MA; 2Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA.

    Purpose: To investigate whether pre-transplant functional status predicts mortality after liver transplant (LT).Methods: We conducted a retrospective cohort study of first-time adult LT recipients using…
  • 2015 American Transplant Congress

    Financial Impact of an Advanced Liver Disease Service on a Tertiary Health System

    A. Masoumi,1 S. Hanish,2 J. LaMattina,2 C. Njoka,1 W. Hutson,2 D. Potosky,2 R. Barth.2

    1University of Maryland Medical Center, Baltimore; 2University of Maryland School of Medicine, Baltimore.

    Regional disparities in liver transplantation motivated revision of national organ-sharing policies towards critically ill patients. Liver transplantation of high MELD patients incorporates significant institutional commitment…
  • 2015 American Transplant Congress

    MiR-26a Regulates Mouse Hepatocyte Proliferation By Directly Targeting Their 3′ Untranslated Region of CCNE2/CCND2

    J. Zhou, X. Yuan, W. Ju, X. Jiao, X. Wang, M. Han, D. Wang, X. Zhu, X. He.

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    Objectives: The deficiency of liver regeneration needs to be addressed in the fields of liver surgery, split liver transplantation and living donor liver transplantation. Researches…
  • 2015 American Transplant Congress

    Live Donor Vs Deceased Donor Liver Transplantation Results in Identical Outcome in Recipients With Acute Liver Failure – An Important Choice for Critical Ill Patients

    N. Goldaracena, G. Sapisochin, J. Echeverri, M. Kaths, N. Selzner, M. Cattral, P. Greig, L. Lilly, I. McGilvray, G. Levy, A. Ghanekar, E. Renner, D. Grant, M. Selzner.

    Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.

    Introduction: Live donor liver transplantation (LDLT) is a valid alternative to deceased donor liver transplantation (DDLT) in patients suffering from acute liver failure (ALF). Rapid…
  • 2015 American Transplant Congress

    The Predictive Value of the Proliferation Marker Ki-67 in Patients With Fulminant Hepatic Failure

    A. Shah,1 U. Joneja,2 D. Walls,1 J. Farber.2

    1Surgery, Thomas Jefferson University, Philadelphia, PA; 2Pathology, Thomas Jefferson University, Philadelphia, PA.

    This study aimed to evaluate the prognostic significance of the cellular proliferation marker Ki-67 in the liver biopsies of patients with fulminant hepatic failure.Under IRB…
  • 2015 American Transplant Congress

    Severe Sarcopenia and Increased Fat Stores in Pediatric Patients With Liver, Kidney and Intestine Failure

    W. Bush, C. Miller, C. Kubal, J. Fridell, A. Tector, R. Mangus.

    Transplant Division, Dept of Surgery, Indiana University School of Medicine, Indianapolis, IN.

    Background: Recent research suggests that measures of frailty, such as nutrition status, may be important predictors of surgical and transplant outcomes. The objectively calculated degree…
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