ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver failure"

  • 2020 American Transplant Congress

    A Quality Improvement Project to Reduce the Risk of Alcohol Relapse after Liver Transplantation by Implementing a High-Risk Alcoholism Relapse Scale

    R. V. Tholen1, E. Bundy2

    1Transplant Nephrology, University of Maryland Medical Center, Baltimore, MD, 2School of Nursing, University of Maryland, Baltimore, Baltimore, MD

    *Purpose: Alcoholism is the leading cause of liver-related mortality worldwide. Liver transplantation is considered the only curative treatment for end-stage liver disease. Transplantation will reverse…
  • 2020 American Transplant Congress

    Increased Level of Serum Cholesterol and Apoptosis Together Induces the Development of Liver Fibrosis and Early Allograft Loss

    B. H. Ozdemir1, G. Ozgun1, E. H. Ayvazoglu Soy2, N. Haberal1, M. Haberal2

    1Pathology, Baskent University, Ankara, Turkey, 2Department of General Surgery, Division of Transplantation, Baskent University, Ankara, Turkey

    *Purpose: Hypercholesterolemia (HC) induced oxidative stress known to facilitate apoptosis, steatosis, and TGF-β induced liver injury. Apoptosis, in turn, can trigger inflammation, and fibrosis. Apoptotic…
  • 2020 American Transplant Congress

    Rapid Preparation to Undergo ABO-Incompatible Living Donor Liver Transplantation for Acute Liver Failure

    H. Hung1, C. Lee2, Y. Wang1, J. Lee2, C. Cheng1, T. Wu1, T. Wu1, H. Chou1, K. Chan1, W. Lee2

    1Chang-gung Hospital, Taoyuan, Taiwan, 2Chang-gung Hospital, Taiyuan, Taiwan

    *Purpose: Acute liver failure is a life-threatening condition and urgent liver transplantation is needed to save lives. In the circumstance of deceased and ABO-compatible (ABO-C)…
  • 2020 American Transplant Congress

    Acute Liver Failure Etiology is an Independent Predictor of Waitlist Outcome Accounting for Severity of Illness in a National Cohort

    N. Z. Wong, K. R. Reddy, T. Bittermann

    University of Pennsylvania, Philadelphia, PA

    *Purpose: Severity of illness and liver transplant (LT) waitlist outcome can differ according to acute liver failure (ALF) etiology. However, it is unknown whether ALF…
  • 2020 American Transplant Congress

    Transplant Center Effect on Acute Liver Failure Outcomes in a National Cohort

    N. Z. Wong, K. R. Reddy, T. Bittermann

    University of Pennsylvania, Philadelphia, PA

    *Purpose: Transplant centers coordinate complex care for patients with acute liver failure (ALF), in whom liver transplantation (LT) can be lifesaving. This study examines associations…
  • 2019 American Transplant Congress

    Hyperglycemia Aggravates Acute Liver Injury by Promoting Macrophage NLRP3 Activation via AMPK/mTOR-Dependent Autophagy Inhibition

    H. ZHOU, Q. Wang, R. Liu, S. Zhou, F. Cheng, X. Wang, L. Lu

    The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    *Purpose: The detrimental effects of diabetes mellitus/hyperglycemia include an increase in the oxidative stress response and an enhanced inflammatory response. Despite an increased understanding of…
  • 2019 American Transplant Congress

    CHOP Deficiency Attenuated Acute Liver Injury by Promoting Macrophage M2 Polarization via ATG5-Mediated Autophagy Activation

    H. Zhou, R. Liu, Q. Wang, C. Shi, F. Cheng, X. Wang, L. Lu

    The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    *Purpose: Critical roles of CCAAT-Enhancer-Binding Protein Homologous Protein (CHOP) have been found in mediating acute liver injury. The aim of this study is to determine…
  • 2019 American Transplant Congress

    Case Series: Anti-Thymocyte Globulin as a Treatment for Steroid-Refractory Severe Acute Hepatitis in Children

    A. L. Peters, A. Miethke, K. Campbell

    Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    *Purpose: Pediatric severe acute hepatitis (SAH), when not attributed to acetaminophen toxicity, is commonly hypothesized to be caused by a non-typeable viral infection and/or immune…
  • 2019 American Transplant Congress

    Liver Transplantation for Acute Liver Failure: A 16 Year Experience with 214 Patients in the Post-MELD Era

    R. McMillan, T. Ito, A. Aziz, A. Amin, A. Murray, J. DiNorcia III, V. G. Agopian, H. Yersiz, D. G. Farmer, R. W. Busuttil, F. M. Kaldas

    Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA

    *Purpose: Liver transplantation (LT) remains the gold standard treatment for acute liver failure (ALF). Our center has previously reported outcomes in the pre-Model for End…
  • 2019 American Transplant Congress

    Patterns Of Anti-retroviral Use Among U.s. Liver Transplant Candidates With Hiv

    A. A. Shaffer1, A. G. Thomas2, D. L. Segev3

    1Johns Hopkins University, Baltimore, MD, 2Epidemiology, University of North Carolina, Chapel Hill, NC, 3Surgery & Epidemiology, Johns Hopkins University, Baltimore, MD

    *Purpose: There is a high burden of liver disease among HIV-infected (HIV+) individuals, and the class of antiretroviral therapy (ART) used for their treatment may…
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