Articles tagged "Liver cirrhosis"

2020 American Transplant Congress
Frailty Attenuates the Gender Gap in Waitlist Mortality in Liver Transplant Candidates: A Multi-Center Study with 1,240 Patients with Cirrhosis
J. C. Lai¹, D. R. Ganger², M. L. Volk³, J. L. Dodge¹, M. A. Dunn⁴, A. Duarte-Rojo⁵, M. R. Kappus⁶, R. S. Rahimi⁷, D. Ladner², B. Boyarsky⁸, M. McAdams-DeMarco⁸, D. L. Segev⁸, C. E. McCulloch¹, E. Verna⁹
¹UCSF, San Francisco, CA, ²NW, Chicago, IL, ³Loma Linda Univ, Loma Linda, CA, ⁴UPMC, Pittsburgh, CA, ⁵UPMC, Pittsburgh, PA, ⁶Duke, Durham, NC, ⁷Baylor, Dallas, TX, ⁸JHMI, Baltimore, MD, ⁹Columbia, New York, NY
*Purpose: Women LT candidates experience higher rates of waitlist mortality than men. Frailty is a critical determinant of mortality in patients with cirrhosis but it…
2020 American Transplant Congress
The Association between Infection and Important Clinical Outcomes in Acute-On-Chronic Liver Patients Admitted to ICU: A Single Center Cohort Analysis
M. Kim¹, A. Pawlowski², R. G. Wunderink³, D. P. Ladner⁴, C. J. Karvellas⁵
¹Neurology, Northwestern University, Chicago, IL, ²Northwestern University, Chicago, IL, ³Medicine, Northwestern University, Chicago, IL, ⁴Surgery, Northwestern University, Chicago, IL, ⁵Medicine, University of Alberta, Edmonton, AB, Canada
*Purpose: One of the most common precipitants of acute on chronic liver failure (ACLF) in cirrhotic patients is sepsis. We aimed to evaluate the relationship…
2020 American Transplant Congress
Karnofsky Performance Status Significantly Increases Waitlist Mortality among Different Grades of Acute on Chronic Liver Failure
A. Ashhab¹, R. Wong², V. Sundaram¹
¹Cedars Sinai Medical Center, Los Angeles, CA, ²Alameida Health System, Oakland, CA
*Purpose: Acute on chronic liver failure (ACLF) is a condition associated with high waitlist mortality and graded according to the number of organ system failures…
2020 American Transplant Congress
Pre-Transplant Overt Hepatic Encephalopathy is Associated with Greater Cognitive Improvement after Liver Transplant
M. Kim¹, J. Menzel-Smith¹, J. D. Peipert², K. J. Reid¹, P. Zee¹, D. P. Ladner³
¹Neurology, Northwestern University, Chicago, IL, ²Northwestern University, Chicago, IL, ³Surgery, Northwestern University, Chicago, IL
*Purpose: Persistent or residual cognitive impairment following liver transplant is frequently reported yet not well-characterized.*Methods: Cognitive function was tested in a prospective cohort of patients…
2020 American Transplant Congress
Risk Prediction in the Meld-NA Era: The Tremendous Impact of Liver Related Complications
N. R. Mazumder¹, K. Atiemo², K. Jackson³, A. Daud⁴, A. Kho³, J. Levitsky¹, D. P. Ladner⁴
¹Gastroenterology and Hepatology, Northwestern University, Chicago, IL, ²Transplant Surgery, Tulane, New Orleans, LA, ³Center for Health Information Partnerships, Institute for Public Health and Medicine, Northwestern University, Chicago, IL, ⁴Transplant Surgery, Northwestern University, Chicago, IL
*Purpose: The MELD-Na score widely used for medical decision making but is not a good predictor of patient outcomes at low scores. Although portal hypertensive…
2020 American Transplant Congress
Live Donor Liver Transplant Offers Higher Survival, Improved Quality of Liver and Lower Morbidity for Recipients with Low MELD Score
M. Black, J. Bayer, H. Fernandez, E. Martinez, G. McKenna, N. Onaca, R. Ruiz, G. Testa, A. Wall, T. Ma, G. Saracino, S. Asrani, A. Gupta
Baylor University Medical Center, Dallas, TX
*Purpose: The shortage of cadaveric liver grafts contributes to significant waitlist mortality. Patients with low MELD-Na score (
2020 American Transplant Congress
Introducing the Smartphone App, EL-FIT (Exercise & Liver FITness), to Help Monitor and Prehabilitate Liver Transplant Candidates
A. Duarte-Rojo¹, P. M. Bloomer¹, R. J. Rogers², M. A. Dunn¹, E. B. Tapper³, R. Bataller¹, C. B. Hughes¹, A. A. Ferrando¹, W. R. Kim⁴, J. M. Jakicic²
¹University of Pittsburgh Medical Center, Pittsburgh, PA, ²University of Pittsburgh, Pittsburgh, PA, ³University of Michigan, Ann Arbor, MI, ⁴Stanford University, Palo Alto, CA
*Purpose: Physical activity is key to liver transplant (LT) prehabilitation, and leveraging technologies to monitor physical performance and to generalize training may be advantageous. EL-FIT…
2020 American Transplant Congress
The Relationship Between Frailty and Performance Status in Patients with Cirrhosis Awaiting Liver Transplantation
C. Q. Xu¹, F. Yao², Y. Mohamad², R. Wong², D. Kent², S. Seetharaman², Y. Srisengfa², J. C. Lai²
¹Department of Medicine, UCSF, San Francisco, CA, ²Division of Gastroenterology and Hepatology, Department of Medicine, UCSF, San Francisco, CA
*Purpose: Frailty—a multi-dimensional construct that encapsulates physical function, performance status, and nutritional status—has emerged as a critical determinant of mortality in patients with cirrhosis. Currently,…
2020 American Transplant Congress
2019 Refined Criteria for Cirrhotic Cardiomyopathy Predict Post Liver Transplant Cardiac Events
M. J. Izzy¹, A. Soldatova², X. Sun², M. Angirekula³, K. Mara⁴, G. Lin², K. Watt³
¹Gastroenterology and Hepatology, Vanderbilt University Medical Center, Nashville, TN, ²Cardiovascular Medicine, Mayo Clinic, Rochester, MN, ³Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, ⁴Health Sciences Research, Mayo Clinic, Rochester, MN
*Purpose: Cirrhotic cardiomyopathy (CCM) encompasses systolic ± diastolic dysfunction (DD) in patients with end stage liver disease in the absence of known cardiac disease. The…
2020 American Transplant Congress
Evolving Trends in Simultaneous Liver Kidney Transplant (SLKT) – Results from the US SLKT Consortium
G. Cullaro¹, J. Jo², J. Rassiwala², L. Van Wagner², R. Wong³, J. C. Lai³, J. Magee⁴, A. Schluger¹, P. Barman⁵, Y. Patel⁵, K. Walters⁶, S. Biggins⁶, P. Sharma⁴, E. C. Verna¹
¹New York Presbyterian, New York, NY, ²Northwestern University, Chicago, IL, ³UCSF, San Francisco, CA, ⁴University of Michigan, Ann Arbor, MI, ⁵Duke University, Durham, NC, ⁶University of Washington, Seattle, WA
*Purpose: The utilization of SLKT in the United States is rising in the MELD era. We aimed to understand the contemporary changes in characteristics and…

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