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Articles tagged "Liver cirrhosis"

  • 2020 American Transplant Congress

    Live Donor Liver Transplant Offers Higher Survival, Improved Quality of Liver and Lower Morbidity for Recipients with Low MELD Score

    M. Black, J. Bayer, H. Fernandez, E. Martinez, G. McKenna, N. Onaca, R. Ruiz, G. Testa, A. Wall, T. Ma, G. Saracino, S. Asrani, A. Gupta

    Baylor University Medical Center, Dallas, TX

    *Purpose: The shortage of cadaveric liver grafts contributes to significant waitlist mortality. Patients with low MELD-Na score (
  • 2020 American Transplant Congress

    Introducing the Smartphone App, EL-FIT (Exercise & Liver FITness), to Help Monitor and Prehabilitate Liver Transplant Candidates

    A. Duarte-Rojo1, P. M. Bloomer1, R. J. Rogers2, M. A. Dunn1, E. B. Tapper3, R. Bataller1, C. B. Hughes1, A. A. Ferrando1, W. R. Kim4, J. M. Jakicic2

    1University of Pittsburgh Medical Center, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3University of Michigan, Ann Arbor, MI, 4Stanford University, Palo Alto, CA

    *Purpose: Physical activity is key to liver transplant (LT) prehabilitation, and leveraging technologies to monitor physical performance and to generalize training may be advantageous. EL-FIT…
  • 2020 American Transplant Congress

    The Relationship Between Frailty and Performance Status in Patients with Cirrhosis Awaiting Liver Transplantation

    C. Q. Xu1, F. Yao2, Y. Mohamad2, R. Wong2, D. Kent2, S. Seetharaman2, Y. Srisengfa2, J. C. Lai2

    1Department of Medicine, UCSF, San Francisco, CA, 2Division of Gastroenterology and Hepatology, Department of Medicine, UCSF, San Francisco, CA

    *Purpose: Frailty—a multi-dimensional construct that encapsulates physical function, performance status, and nutritional status—has emerged as a critical determinant of mortality in patients with cirrhosis. Currently,…
  • 2020 American Transplant Congress

    2019 Refined Criteria for Cirrhotic Cardiomyopathy Predict Post Liver Transplant Cardiac Events

    M. J. Izzy1, A. Soldatova2, X. Sun2, M. Angirekula3, K. Mara4, G. Lin2, K. Watt3

    1Gastroenterology and Hepatology, Vanderbilt University Medical Center, Nashville, TN, 2Cardiovascular Medicine, Mayo Clinic, Rochester, MN, 3Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, 4Health Sciences Research, Mayo Clinic, Rochester, MN

    *Purpose: Cirrhotic cardiomyopathy (CCM) encompasses systolic ± diastolic dysfunction (DD) in patients with end stage liver disease in the absence of known cardiac disease. The…
  • 2020 American Transplant Congress

    Evolving Trends in Simultaneous Liver Kidney Transplant (SLKT) – Results from the US SLKT Consortium

    G. Cullaro1, J. Jo2, J. Rassiwala2, L. Van Wagner2, R. Wong3, J. C. Lai3, J. Magee4, A. Schluger1, P. Barman5, Y. Patel5, K. Walters6, S. Biggins6, P. Sharma4, E. C. Verna1

    1New York Presbyterian, New York, NY, 2Northwestern University, Chicago, IL, 3UCSF, San Francisco, CA, 4University of Michigan, Ann Arbor, MI, 5Duke University, Durham, NC, 6University of Washington, Seattle, WA

    *Purpose: The utilization of SLKT in the United States is rising in the MELD era. We aimed to understand the contemporary changes in characteristics and…
  • 2020 American Transplant Congress

    Bacterial Infection in Compensated Cirrhosis Predicts Inpatient Mortality and Readmission with Decompensation

    R. Rosenblatt1, A. Jesudian1, C. Lucero1, A. Kaplan1, R. S. Brown1, V. Sundaram2, B. Fortune1

    1Weill Cornell Medicine, New York, NY, 2Cedars Sinai, Los Angeles, CA

    *Purpose: Identify the impact of bacterial infection on inpatient mortality and new decompensation in hospitalized patients with compensated cirrhosis from a nationally representative database.*Methods: This…
  • 2020 American Transplant Congress

    Challenges in Examining Transplant Outcomes in Patients with Fontan-Associated Liver Disease

    R. T. Fischer1, M. H. Kim2, A. Nguyen3, S. R. Kumar3, J. Bucuvalas4, E. F. Glynn1, M. A. Hoffman1, J. Emamaullee3

    1Children's Mercy Hospital, Kansas City, MO, 2Children's Hospital-Los Angeles, Los Angeles, CA, 3University of Southern California, Los Angeles, CA, 4Mount Sinai Kravis Children's Hospital, New York, NY

    *Purpose: The Fontan procedure has allowed patients born with single ventricle physiology to survive into adulthood. It is projected that the mean age of Fontan…
  • 2020 American Transplant Congress

    Identification of Molecular Markers for Liver Cirrhosis (NASH) by Single-Nucleus RNA Sequencing

    C. Kuscu1, A. Mouhammed2, C. Kuscu3, A. R. Wolen3, J. D. Eason3, D. Maluf3, V. Mas3

    1Dept of Surgery, Transplant Research Institute, James D. Eason Transplant Institute, University of Tennessee Health Science Center, Memphis, TN, 2Bioinformatics, University of Tennessee Health Science Center, Memphis, TN, 3Department of Surgery, University of Tennessee Health Science Center, Memphis, TN

    *Purpose: Non-alcoholic fatty liver disease (NAFLD) is a progressive disease and it constitutes a significant portion of the chronic liver diseases that affected more than…
  • 2020 American Transplant Congress

    Child-Turcotte-Pugh Class at Transplantation Predicts Mortality after Heart Transplantation Following Left Ventricular Assist Device Placement

    E. Leven1, A. T. Kurdi2, S. Pinney1, T. Schiano1, J. Crismale1

    1Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, 2Gastroenterology, Mayo Clinic, Rochester, MN

    *Purpose: The primary aim of this study is to assess whether Child-Turcotte-Pugh (CTP) class is associated with mortality in end-stage heart disease patients undergoing left…
  • 2020 American Transplant Congress

    Evaluation of Pre-Transplant T Cell Exhaustion as a Mechanism for Immune Dysfunction and Recipient Risk of Death Following Liver Transplant

    K. E. Lunsford1, N. Aware2, K. Cleveland3, D. T. Nguyen4, E. A. Graviss4, L. J. Minze3, T. N. Eagar4, X. C. Li3, R. M. Ghobrial3

    1Department of Surgery, Rutgers New Jersey Medical School, Newark, NJ, 2Department of Surgery, Houston Methodist Hosptial, Houston, TX, 3Department of Surgery, Houston Methodist Hospital, Houston, TX, 4Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX

    *Purpose: Cirrhosis-related immune dysfunction likely contributes to early mortality following liver transplant (LT) resulting from infections. We previously identified a pre-transplant biomarker panel for immune…
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