Articles tagged "Liver cirrhosis"

2020 American Transplant Congress
Challenges in Examining Transplant Outcomes in Patients with Fontan-Associated Liver Disease
R. T. Fischer¹, M. H. Kim², A. Nguyen³, S. R. Kumar³, J. Bucuvalas⁴, E. F. Glynn¹, M. A. Hoffman¹, J. Emamaullee³
¹Children's Mercy Hospital, Kansas City, MO, ²Children's Hospital-Los Angeles, Los Angeles, CA, ³University of Southern California, Los Angeles, CA, ⁴Mount Sinai Kravis Children's Hospital, New York, NY
*Purpose: The Fontan procedure has allowed patients born with single ventricle physiology to survive into adulthood. It is projected that the mean age of Fontan…
2020 American Transplant Congress
Identification of Molecular Markers for Liver Cirrhosis (NASH) by Single-Nucleus RNA Sequencing
C. Kuscu¹, A. Mouhammed², C. Kuscu³, A. R. Wolen³, J. D. Eason³, D. Maluf³, V. Mas³
¹Dept of Surgery, Transplant Research Institute, James D. Eason Transplant Institute, University of Tennessee Health Science Center, Memphis, TN, ²Bioinformatics, University of Tennessee Health Science Center, Memphis, TN, ³Department of Surgery, University of Tennessee Health Science Center, Memphis, TN
*Purpose: Non-alcoholic fatty liver disease (NAFLD) is a progressive disease and it constitutes a significant portion of the chronic liver diseases that affected more than…
2020 American Transplant Congress
Child-Turcotte-Pugh Class at Transplantation Predicts Mortality after Heart Transplantation Following Left Ventricular Assist Device Placement
E. Leven¹, A. T. Kurdi², S. Pinney¹, T. Schiano¹, J. Crismale¹
¹Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, ²Gastroenterology, Mayo Clinic, Rochester, MN
*Purpose: The primary aim of this study is to assess whether Child-Turcotte-Pugh (CTP) class is associated with mortality in end-stage heart disease patients undergoing left…
2020 American Transplant Congress
Evaluation of Pre-Transplant T Cell Exhaustion as a Mechanism for Immune Dysfunction and Recipient Risk of Death Following Liver Transplant
K. E. Lunsford¹, N. Aware², K. Cleveland³, D. T. Nguyen⁴, E. A. Graviss⁴, L. J. Minze³, T. N. Eagar⁴, X. C. Li³, R. M. Ghobrial³
¹Department of Surgery, Rutgers New Jersey Medical School, Newark, NJ, ²Department of Surgery, Houston Methodist Hosptial, Houston, TX, ³Department of Surgery, Houston Methodist Hospital, Houston, TX, ⁴Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX
*Purpose: Cirrhosis-related immune dysfunction likely contributes to early mortality following liver transplant (LT) resulting from infections. We previously identified a pre-transplant biomarker panel for immune…
2020 American Transplant Congress
Acute on Chronic Liver Failure (ACLF) Patients Have a Dynamic and Progressive Clinical Course Until Receiving a Liver Transplant: A 5-Year Study at the National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico
E. Cervantes-Alvarez¹, M. J. Lizardo-Thiebaud¹, E. Alatorre-Arenas¹, O. Mendez-Guerrero¹, S. Yarza-Regalado¹, A. Torre¹, M. Vilatobá², D. Kershenobich¹, C. A. Huang³, N. Navarro-Alvarez¹
¹Gastroenterology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ²Surgery, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ³Surgery, University of Colorado Anschutz Medical Campus, DENVER, CO
*Purpose: To characterize the clinical course of patients diagnosed with acute on chronic liver failure (ACLF) before undergoing liver transplantation. ACLF is characterized by an…
2020 American Transplant Congress
Black Patients with Cirrhosis Have Worse Liver-Related Outcomes: A Large Multicenter Study
N. R. Mazumder¹, K. Atiemo², K. Jackson³, A. Daud⁴, A. Kho³, L. G. Gabra⁵, J. Levitsky¹, D. P. Ladner⁴
¹Gastroenterology and Hepatology, Northwestern University, Chicago, IL, ²Department of Surgery, Tulane Abdominal Transplant Institute, New Orleans, LA, ³Center for Health Information Partnerships, Northwestern University, Chicago, IL, ⁴Transplant Surgery, Northwestern University, Chicago, IL, ⁵Feinberg School of Medicine, Northwestern University, Chicago, IL
*Purpose: Racial disparity is influential in liver cirrhosis. Estimates of its magnitude have been limited by lack of large, longitudinal data that track patients from…
2020 American Transplant Congress
Galectin-3 as a Biomarker of Disease Severity in Acute-on-Chronic Liver Failure
E. Cervantes-Alvarez¹, F. Tejeda-Dominguez², M. Lizardo-Thiebaud², E. Alatorre-Arenas³, O. Méndez-Guerrero¹, S. Yarza-Regalado¹, D. Kershenobich¹, A. Torre¹, M. Vilatobá⁴, C. A. Huang⁵, N. Navarro-Alvarez¹
¹Gastroenterology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ²Molecular Biology, Panamerican University, School of Medicine, Mexico City, Mexico, ³University of the Americas Puebla, School of Medicine, Puebla, Mexico, ⁴Surgery, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ⁵Surgery, University of Colorado Anschutz Medical Campus, Denver, CO
*Purpose: A matter of great importance is the discovery of alternative diagnostic measures that can detect liver disease at an early stage, especially when at…
2020 American Transplant Congress
Safety and Efficacy of Endoscopic Transpapillary Gallbladder Stenting for Symptomatic Gallbladder Disease in Cirrhosis: A Systematic Review and Meta-Analysis
K. F. Haq¹, U. Iqbal², M. Khan³, F. Kamal⁴, S. Solanki⁵, R. Chakinala⁵, M. Siddiqui¹, M. Abu Ghanimeh¹, O. Sadiq¹, A. Watson¹, T. Zuchelli¹, R. Salgia¹
¹Gastroenterology & Hepatology, Henry Ford Hospital, Detroit, MI, ²Medicine, Geisinger Medical Center, Danville, PA, ³Gastroenterology & Hepatology, University of Alabama, Birmingham, AL, ⁴Gastroenterology & Hepatology, University of Tennessee, Knoxville, TN, ⁵Medicine, Guthrie Hospital, Sayre, PA
*Purpose: Endoscopic transpapillary gallbladder (cystic duct) stenting has been shown to be an effective treatment option for symptomatic gallbladder disease in patients with cirrhosis. However,…
2020 American Transplant Congress
Impact of Donor Noninvasive Liver Fibrotic Score on Graft Injury in Liver Transplantation
S. M. Younan, T. Ito, H. Hirao, A. Aziz, A. E. Murray, J. DiNorcia III, V. G. Agopian, D. G. Farmer, R. W. Busuttil, F. M. Kaldas
The Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: The increasing prevalence of obesity and metabolic syndrome, has led to a corresponding increase in steatotic livers being utilized in liver transplantation (LT). These…
2020 American Transplant Congress
Frailty Prior to Hospital Discharge Predicts Mortality after Cirrhosis-Related Admissions
M. Serper¹, S. Tao², P. Garren¹, D. Peyton¹, M. A. Dunn², K. Reddy¹, A. Gougol², A. Duarte-Rojo²
¹University of Pennsylvania, Philadelphia, PA, ²University of Pittsburgh, Pittsburgh, PA
*Purpose: Inpatient frailty assessment and its utility in clinical care is understudied in liver transplant (LT) candidates. Study objectives were to quantify physical frailty among…

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