2022 American Transplant Congress
Cell-free Amniotic Fluid Reduces Liver Inflammation And Fibrosis
*Purpose: Effective interventions for hepatic inflammation and fibrosis remain a dire unmet need in transplant medicine. Cell-free amniotic fluid (AF) represents a potential alternative to…2022 American Transplant Congress
Cognitive Impairment In Liver Transplant Recipients 6 Months Or More After Transplant
*Purpose: Patients with decompensated cirrhosis awaiting liver transplant (LT) exhibit a spectrum of neurocognitive disorders, largely attributed to hepatic encephalopathy (HE) and considered reversible after…2022 American Transplant Congress
Transplant Combined with Neoadjuvant Therapy Improves Survival for Patients with Liver-Limited, Locally Advanced Intrahepatic Cholangiocarcinoma: A SEER Database Analysis
*Purpose: Preliminary single-center data suggest multimodal therapy may improve outcomes for patients with intrahepatic cholangiocarcinoma (iCCA) undergoing liver transplant (LT), particularly in the setting of…2022 American Transplant Congress
Integrated Alcohol Use Disorder Clinic as a Strategy to Reduce Alcohol Relapse After Early Liver Transplantation in Patients with Alcohol Related Liver Disease
*Purpose: In recent years, for patients with Alcohol related Liver Disease (ALD), there has been a trend towards early Liver Transplantation (LT) rather than waiting…2022 American Transplant Congress
Gender Affects the Association Between Serum Creatinine Levels and Clinical Response to Terlipressin in Patients with Hepatorenal Syndrome Type of Acute Kidney Injury
*Purpose: Hepatorenal syndrome (HRS)-acute kidney injury (AKI) is a rare and serious complication of cirrhosis, with serum creatinine (SCr) used diagnostically. Women generally have less…2022 American Transplant Congress
Early Mortality After Liver Transplant is Associated with Pre-Transplant Alterations in Monocyte Phenotype and Gene Expression
*Purpose: Persistence of pre-liver transplant (LT) immune dysfunction (immune frailty) significantly increases post-LT morbidity and mortality. We have identified a pre-LT biomarker panel, the liver…2022 American Transplant Congress
Kidney Transplant Alone Recipients with Advanced Liver Disease Have Similar Outcomes to Those without Advanced Liver Disease
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: The prevalence of concomitant liver disease (CLD) in patients with ESRD is reported to be 7-40%. Safety of kidney transplant alone (KTA) in those…2022 American Transplant Congress
Galectin-3 Discriminates Patients with Advanced Cirrhosis and Predicts Post-Liver Transplant Infectious Complications
*Purpose: An increased demand for liver transplantation (LT) prevails. Galectin-3 is a lectin implicated in inflammation, immunoregulation, and liver fibrosis. In this study we assessed…2022 American Transplant Congress
Patient-Reported Physical Function Correlates with Liver Frailty Index and 4-Meter Gait Speed in Patients with Cirrhosis
Northwestern University Feinberg School of Medicine, Chicago, IL
*Purpose: Frailty is highly prevalent in patients with end-stage liver disease and strongly predicts waitlist and post-transplant mortality. The Liver Frailty Index (LFI) and 4-meter…2022 American Transplant Congress
Higher Baseline Serum Creatinine Levels AreAssociated with an Increased Incidence of Renal Replacement Therapy in Patients with Hepatorenal Syndrome Type 1 on the Liver Transplant Waitlist
*Purpose: Pretransplant and posttransplant renal replacement therapy (RRT) is associated with increased morbidity and mortality in liver transplant recipients, including those with Hepatorenal syndrome type…
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