ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Leukocytes"

  • 2015 American Transplant Congress

    AAV-Mediated TIMP-1 Gene Therapy Ameliorates Hepatic Ischemia/Reperfusion Injury

    S. Duarte, T. Fujii, G. Lipshutz, R. Busuttil, A. Coito.

    The Dumont-UCLA Transplant Center, Los Angeles.

    Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase-1 (TIMP-1) is the…
  • 2015 American Transplant Congress

    Differential Intragraft Gene Expression Profiles in Patients With Sterile Leukocyturia

    M. Ajaimy,1 P. O Broin,2 Y. Bao,1 J. Lindower,1 A. Golden,2 E. Akalin.1

    1Transplantation, Einstein/Montefiore Transplant Center, Bronx; 2Computational Genomics Facility, Albert/Einstein College of Medicine, Bronx.

    Objective: We aimed to investigate if sterile leukocyturia reflects increased intragraft immune activity and gene expression profiles of transplant kidney biopsies differ from patients without…
  • 2015 American Transplant Congress

    Does PTH Play a Role in Post Kidney Transplant Leukopenia?

    R. Dhawan, L. Shin, K. Lee, B. Duong, L. Aguirre, C. Parke, S. Alexopoulos, M. Smogorzewski, A. Gomez, E. Mariscal, L. Matsuoka, Y. Qazi.

    Division of Transplantation, University Of Southern California. Keck Med Center, Los Angeles, CA.

    Aim : Recent data suggests a role of Parathyroid hormone (PTH) on hematopoietic stem cell progenitor cells(HSPCs)[1,2]. The purpose of the study was determine the…
  • 2015 American Transplant Congress

    Recipient Myelomonocytic Cells With Activated Hypoxia-Inducible Factor Alleviate Ischemia-Reperfusion Injury in Mouse Heart Allografts

    A. Raissadati, M. Keränen, E. Rouvinen, R. Krebs, K. Lemström.

    Transplantation Laboratory and Department of Cardiac Surgery, University of Helsinki, Haartman institute and Helsinki University Central Hospital, Heart and Lung Center, Helsinki, Finland.

    Aim: To investigate the effect of HIF-1α and -2α activation in myelomonocytic cells during the early phase after ischemia-reperfusion (IRI) injury of mouse allogenic heart…
  • 2015 American Transplant Congress

    Neogenin Functions as a Chemokinetic Receptor on Activated CD4+ T Lymphocytes

    L. Boneschansker,1 H. Nakayama,1 M. Eisenga,1 M. Klagsbrun,1 D. Irimia,2 D. Briscoe.1

    1Boston Children's Hospital, Boston; 2Massachusetts General Hospital, Boston.

    Increasing data indicates that axonal guidance cues play a critical role in immunity, both in activation, migration as well as in the process of inflammation…
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