Articles tagged "Kidney/pancreas transplantation"

2017 American Transplant Congress
The Paradox in Pancreas After Kidney Transplantation (PAK): Better Results but Fewer Transplants Despite an Increase in High-Risk Patients.
O. Pankewycz,¹ A. Gruessner,² M. Laftavi,² V. Whittaker,² V. Aggarwal,¹ R. Gruessner.²
¹Medicine, Upstate Medical University, Syracuse, NY; ²Surgery, Upstate Medical University, Syracuse, NY
Background: The number of pancreas transplants performed in the United States peaked in 2004 at 1,483. Since then, pancreas transplant numbers have significantly decreased. Between…
2017 American Transplant Congress
Survival Benefit of Kidney and/or Pancreas Transplantation for Patients with Type 1 Diabetes in the United States.
R. Gruessner,¹ M. Laftavi,¹ O. Pankowycz,² V. Whittaker,¹ Z. Acun,¹ V. Aggarwal,² N. Ozden,² A. Gruessner.¹
¹Surgery, SUNY Upstate Medical University, Syracuse, NY; ²Internal Medicine, SUNY Upstate Medical University, Syracuse, NY
Study Purpose: The purpose of this study was to determine the survival benefit of pancreas and/or kidney transplants as reported over a 28-year time period…
2017 American Transplant Congress
Simultaneous Pancreas and Kidney Transplant (SPK) – The New Standard of Care for Uremic Patients with Type 2 Diabetes Mellitus (T2DM).
A. Gruessner, M. Laftavi, V. Whittaker, Z. Acun, O. Pankowycz, R. Gruessner.
Surgery, SUNY Upstate Medical University, Syracuse, NY
Introduction: While a SPK is now considered standard of care for uremic T1 DM patients, it is not for T2DM (despite similar medical issues). The…
2017 American Transplant Congress
Utility of Concomitant Biopsy in Simultaneous Pancreas Kidney Transplant Recipients in the Identification of Rejection of Pancreas and Kidney.
C. Johnson, K. Johnson, B. Kaplan, M. Temkit, R. Heilman, S. Sukumaran Nair, H. Khamash, J. Huskey, G. Mour, H. Chakkera.
Mayo Clinic Arizona, Phoenix, AZ
Background: In simultaneous pancreas and kidney transplant (SPKTx) recipients, animal studies suggest concordant rejection rates of 88% (ref: Gruessner et al,1994). Limited information is available…
2017 American Transplant Congress
Elevated Serum Lipase Levels in Simultaneous Pancreas and Kidney Transplantation May Indicate Anti-HLA Donor Specific Antibody Response.
B. Javaid, T. Raza, P. Abrams, S. Ghasemian, J. Moore, A. Gilbert, M. Grafals, J. Verbesey, M. Cooper.
Kidney and Pancreas Transplant Program, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Georgetown University School of Medicine, Washington, DC
Background: Development of anti-HLA donor specific antibodies (DSAs) has been associated with inferior pancreas transplant outcomes. We analyzed data for pancreas and kidney transplant recipients…
2017 American Transplant Congress
Simultaneous Pancreas/Kidney Transplant Recipients Are Predisposed to Symptomatic CMV-Infection and Concomitant Infectious Complications.
T. Schachtner,^1,2,3 M. Zaks,¹ A. Kahl,¹ P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany; ³Berlin Institute of Health BIH, Berlin, Germany
Infections have increased in simultaneous pancreas/kidney transplant recipients (SPKTRs) with CMV-infection being the most important viral infection with adverse impact on patient and allograft outcomes.…
2017 American Transplant Congress
Access to Simultaneous Pancreas and Kidney Transplant (SPK) Should Not Be Restricted to BMI > 28.
M. Laftavi, A. Gruessner, V. Whittaker, Z. Acun, O. Pankowycz, R. Gruessner.
SUNY Upstate Medical University, Syracuse, NY
Background: Currently, UNOS guidelines require that uremic, insulin-dependent type 1 diabetic patients have a body mass index (BMI) < 28m/kg2 in order to be eligible…
2017 American Transplant Congress
Pregnancy After Kidney-Pancreas Transplantation: Maternal and Offspring Outcomes.
S. Rao,¹ L. Coscia,² D. Armenti,² S. Constantinescu,^1,2 M. Moritz.^2,3,4
¹Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA; ²Gift of Life Institute, Transplant Pregnancy Registry International, Philadelphia, PA; ³Surgery, Lehigh Valley Health Network, Allentown, PA; ⁴Morsani College of Medicine, USF, Tampa
This study analyzed 109 pregnancies (116 outcomes) in 62 female kidney-pancreas (KP) recipients reported to the Transplant Pregnancy Registry International (TPR). Data were collected via…
2017 American Transplant Congress
Type 1 Diabetic Patients Have Better Endothelial Function After Simultaneous Pancreas-Kidney Transplantation Than After Kidney Transplantation with Continued Insulin Therapy.
A. Kolonko,² A. Kowalik,¹ J. Ziaja,¹ D. Kaminska,³ A. Owczarek,⁴ A. Kujawa-Szewieczek,² M. Kusztal,³ J. Badura,¹ D. Bozek-Pajak,¹ A. Zakrzewska,⁵ P. Choreza,⁴ R. Krol,¹ S. Chlopicki,⁵ M. Klinger,³ A. Wiecek,² J. Chudek,⁶ L. Cierpka.¹
¹Medical University of Silesia, Katowice, Poland; ²Medical University of Silesia, Katowice, Poland; ³Wroclaw Medical University, Wroclaw, Poland; ⁴Medical University of Silesia, Sosnowiec, Poland; ⁵Jagiellonian University, Krakow, Poland; ⁶Medical University of Silesia, Katowice, Poland
Objective: The improvement of blood glucose metabolism in type 1 diabetic (T1D) patients after simultaneous pancreas-kidney transplantation (SPK) is anticipated to slow progression of vascular…
2017 American Transplant Congress
Donor Age Is the Most Important Predictor of Longterm Graft Function in Simultaneous Pancreas-Kidney Transplantation from Donors After Cardiac Death.
J. Chen,¹ D. Mikhail,^1,2 H. Sharma,³ A. Hijazi,¹ D. Nap,¹ L. Stitt,⁴ J. Jevnikar,⁵ M. Cooper,⁶ P. Luke,^1,2 A. Sener.^1,2
¹Schulich School of Medicine and Dentistry, London, Canada; ²Division of Urology, Department of Surgery, Western University, London, London, Canada; ³Division of General Surgery, Department of Urology, Western University, London, Canada; ⁴LW Stitt Statistical Services, London, Canada; ⁵Faculty of Engineering and Architectural Sciences, Ryerson University, Toronto, Canada; ⁶Georgetown University, Washington
STUDY PURPOSE: We analyzed data from UNOS to determine the effects of donor age, donor BMI, and organ cold ischemic time on DCD-SPK graft outcomes.METHODS:…