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American Transplant Congress abstracts

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Articles tagged "Kidney/liver transplantation"

  • 2020 American Transplant Congress

    Utilization of Organs from Donors Exposed to Hepatitis C: ? Standard of Care

    M. Marvin1, S. Gaines2, P. Mohan3, A. Kotru1, C. Koo1, B. Addissie4, A. Unzueta4, S. Khurana4

    1Transplantation and Liver Surgery, Geisinger, Danville, PA, 2Pharmacy, Geisinger, Danville, PA, 3Nephrology, Geisinger, Danville, PA, 4Hepatology, Geisinger, Danville, PA

    *Purpose: To report the results of a clinical program to utilize livers and kidneys from donors exposed to Hepatitis C.*Methods: We initially started to explore…
  • 2020 American Transplant Congress

    Ex Vivo Isolated Human Vessel Perfusion System for the Design and Assessment of Nanomedicines Targeted to the Endothelium

    L. G. Bracaglia1, T. Lysyy2, L. Qin2, C. Albert1, J. S. Pober2, G. Tellides2, W. M. Saltzman1, G. T. Tietjen2

    1Yale University, New Haven, CT, 2Yale School of Medicine, New Haven, CT

    *Purpose: In solid organ transplantation the host immune system acts to reject the graft. This process is facilitated at the endothelial surface, where inflamed donor…
  • 2020 American Transplant Congress

    Depression Screening Protocol in Post Transplant Clinic. Implementing the A3 Scientific Method for Improving Patient Safety

    W. M. Potts, A. Anthony, K. Brayman, A. Doyle

    Charles Strickler Transplant Center, University of Virginia Health System, Charlottesville, VA

    *Purpose: Effect of the routine use of Patient Health Questionnaire PHQ-2 Screening in ambulatory transplant clinic to identify patients at risk for self-harm*Methods: Following a…
  • 2020 American Transplant Congress

    Evaluation of Optimization of Workflow for Timing of Inpatient Therapeutic Drug Monitoring of Maintenance Immunosuppressive Drugs in Abdominal Transplant Recipients

    J. Schulte, S. Mehta, E. Vargas, K. Cunningham

    Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Therapeutic drug monitoring (TDM) is essential to the safety and efficacy of immunosuppressants (IS) given their narrow therapeutic index. After an internal review, it…
  • 2020 American Transplant Congress

    ANG-3777, A Hepatic Growth Factor Mimetic, Attenuates Post-Transplant Renal Dysfunction in Rats

    P. Narayan, I. D. Goldberg

    Angion Biomedica, Uniondale, NY

    *Purpose: ANG-3777, a small-molecule mimetic of hepatocyte growth factor (HGF), has the potential to exert antifibrotic and nephroprotective effects. A rat model of renal transplantation…
  • 2019 American Transplant Congress

    Single Nucleotide Polymorphisms in NFACT1 rs2290154 Associated with the Risk of T Cell-Mediated Rejection of Recipients Following Kidney Transplantation

    Z. Wang, S. Fei, H. Chen, L. Sun, Z. Han, J. Tao, X. Ju, R. Tan, M. Gu

    No.300 Guangzhou Road of Nanjing, Nanjing, China

    *Purpose: Our study was to investigate the potential associations between the single nucleotide polymorphisms (SNPs) in NFATC1 and the risk of T cell-mediated rejection (TCMR)…
  • 2019 American Transplant Congress

    Use of a CMV Specific T Cell Immunity Assay in Late-Onset CMV Infection

    O. Beaird1, M. Carlson1, P. Gaynor1, D. Nanayakkara1, B. Abdalla2, S. Bunnapradist2, J. Schaenman1

    1Department of Internal Medicine - Division Infectious Diseases, UCLA, Los Angeles, CA, 2Department of Internal Medicine - Division Nephrology, UCLA, Los Angeles, CA

    *Purpose: To describe our clinical experience using a CMV Specific Cell Mediated Immunity (CMI) assay in solid organ transplant (SOT) recipients with late-onset CMV, defined…
  • 2019 American Transplant Congress

    Consistent High Burden of Arteriosclerosis in Pediatric Kidney Transplant Recipients

    K. Ostendorf1, N. Memaran1, B. Borchert-Mörlins1, J. von der Born1, E. Bauer1, A. von Wick1, J. Oh2, M. J. Kemper3, R. Büscher4, B. M. Schmidt5, A. Melk1

    1Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany, 2Pediatric Nephrology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 3Department of Pediatrics, Asklepios Klinik Nord - Heidberg, Hamburg, Germany, 4Pediatric Nephrology, University Hospital, Essen, Germany, 5Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany

    *Purpose: The second most common cause of death in pediatric kidney transplant (KT) recipients are cardiovascular (CV) diseases. We have previously shown that pulse wave…
  • 2019 American Transplant Congress

    Rapid Growth of HCV-Infected Donors for HCV-Uninfected Kidney and Liver Transplant Recipients in the United States

    M. Bowring, A. Shaffer, A. Massie, N. Desai, M. Sulkowski, A. Cameron, J. Garonzik-Wang, D. Segev

    Johns Hopkins University, Baltimore, MD

    *Purpose: Several single-center reports of using HCV-viremic organs for HCV-uninfected recipients were recently published in the US. In light of recent DAA introduction, we sought…
  • 2019 American Transplant Congress

    Letermovir for CMV Treatment in Solid Organ Transplant

    O. Witkowsky, M. Chunduru, A. Chung, A. Diez

    The Ohio State University Wexner Medical Center, Columbus, OH

    *Purpose: Letermovir (LET), a novel anti-CMV agent, was recently approved for CMV prophylaxis in stem cell transplant recipients and is currently under investigation as a…
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