Articles tagged "Kidney"

2017 American Transplant Congress
Model to Predict Prolonged Delayed Graft Function (DGF) Following Kidney Transplantation from Deceased Donor with Acute Kidney Injury (AKI Tx).
R. Heilman,¹ B. Smith,² C. Johnson,¹ H. Khamash,¹ K. Reddy,¹ W. Kremers,² B. Kaplan.¹
¹Mayo Clinic, Phoenix, AZ; ²Mayo Clinic, Rochester, MN
Background Our aim is to develop a model to predict prolonged DGF following AKI Tx.Methods AKI Tx (donor terminal Cr>/=2) from 2003 to 2016 were…
2017 American Transplant Congress
Lipid Catabolism Provides Alternative Energy Source and Compensates for Mitochondrial Dysfunction in Reperfused Rat Kidneys After Ischaemia.
H. Huang,^1,2 L. van Dullemen,³ M. Akhtar,¹ M. Lo Faro,^1,2 A. Dona,⁴ M. Kaisar,^1,2 H. Leuvenink,³ B. Kessler,² R. Ploeg.¹
¹Oxford Transplant Centre, NDS, University of Oxford, Oxford, United Kingdom; ²Target Discovery Institute, NDM, University of Oxford, Oxford, United Kingdom; ³Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; ⁴Department of Surgery and Cancer, Imperial College London, London, United Kingdom
Introduction: To reduce morbidity and mortality on the wait list for kidney transplantation, centres are required to use older and higher risk organs including unstable…
2017 American Transplant Congress
Urinary Retention Associated with Polyomavirus (BK) Viruria and Higher Peak Blood BK Following Kidney Transplant (KTx).
W. Cheungpasitporn,¹ H. Amer,² F. Cosio,² C. Schinstock.²
¹Nephrology and Hypertension, Mayo Clinic, Rochester, MN; ²The William J von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN
BACKGROUND: BK nephropathy is a major risk factor for allograft dysfunction and loss. BK viruria and viremia are early markers of BK nephropathy in KTx…
2017 American Transplant Congress
Financial Burden and Time to Returning to Work Among Living Kidney Donors.
D. Larson, D. Berglund, D. Vock, A. Roman, J. Wiseman, H. Ibrahim, A. Matas.
U of MN, Mpls
Surveying our living kidney donor (LKD) population we learned (and reported) that: a) more than a quarter of our LKDs experienced substantial financial burden due…
2017 American Transplant Congress
Novel Therapies for Diabetic Kidney Disease.
M. Nguyen, K. Kodama, M. Sarwal.
University of California, San Francisco, San Francisco, CA
Introduction: The development and progression of diabetic kidney disease (DKD) is thought to involve a combination of hemodynamic, metabolic, ischemic, and inflammatory factors; however, the…
2017 American Transplant Congress
The Adoption of Generic Immunosuppressant Medications Among Kidney and Liver Transplant Recipients Using the Colorado All Payer Claims Database.
Q. Liu,¹ A. Smith,¹ J. Park,² M. Oguntimein,³ S. Dutcher,³ G. Bello,¹ M. Helmuth,¹ M. Turenne,¹ R. Balkrishnan,⁴ M. Fava,¹ P. Sharma,² C. Beil,¹ A. Leichtman,¹ J. Zee.¹
¹Arbor Research Collaborative for Health, Ann Arbor, MI; ²U of Michigan, Ann Arbor, MI; ³Food and Drug Administration, Silver Spring, MD; ⁴U of Virginia, Charlottesville, VA
Background: Substitution of generic for brand-name immunosuppressants has increased in solid organ transplantation following the expiration of brand patents. Our aim was to describe the…
2017 American Transplant Congress
Deciphering the Mechanism of Remote Ischemic Preconditioning and Its Potential Benefits in Ischemia/Reperfusion Injury by Metabolomics.
S. Cho, S.-I. Min, S.-Y. Kim, M.-J. Cho, W. Cho, S. Ahn, S.-K. Min, J. Ha.
Surgery, Seoul National University Hospital, Seoul, Korea
IntroductionRemote ischemic preconditioning (RIPC) is a strategy inducing resistance against ischemia and reperfusion(IR) injury. But the mechanism and the time window of protection representing RIPC…
2017 American Transplant Congress
Prescription Opioid Use Before and After Kidney Transplant: Implications for Post-Transplant Outcomes.
K. Lentine,¹ N. Lam,² D. Segev,³ D. Axelrod,⁴ Z. Zhang,¹ H. Xiao,¹ G. Hess,⁵ B. Kasiske,⁶ R. Gadi,¹ R. Devraj,⁷ D. Brennan,⁸ H. Randall,¹ M. Schnitzler.^1,6
¹St. Louis Univ, St. Louis, MO; ²Univ Alberta, Edmonton, AB, Canada; ³Johns Hopkins, Baltimore, MD; ⁴East Carolina Univ, Greenville, NC; ⁵Symphony Health, Philadelphia, PA; ⁶Scientific Registry of Transplant Recipients, Minneapolis, MN; ⁷Southern Illinois Univ, Edwardsville, IL; ⁸Washington Univ, St. Louis, MO
We previously identified associations of opioid use before kidney transplant (KTx) with post-KTx complications.To confirm and extend these findings, we examined a novel database wherein…
2017 American Transplant Congress
Left-Sided Donor Nephrectomy Predisposes Living Kidney Donors to Latent Adrenal Insufficiency with Symptoms of Fatigue and Inferior Quality of Life.
T. Schachtner,^1,2 P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany
The rising prevalence of end-stage renal disease and chronic organ shortage calls more people upon to consider living kidney donation. The benefits for recipients and…
2017 American Transplant Congress
Twelve Hour Ex Vivo Normothermic Perfusion for the Assessment of High-Risk Discarded Deceased Donor Kidneys.
I. Palma, I. Palma, Y. Smolin, S. Kabagambe, A. Perry, J. Sageshima, R. Perez.
Department of Surgery, UC Davis Medical Center, Sacramento, CA
Ex-Vivo Normothermic Perfusion (EVNP) has been shown to be useful to assess viability of high-risk deceased donor kidneys, with high renal blood flow and immediate…