Articles tagged "Kidney"

2018 American Transplant Congress
Simultaneous versus Pretransplant Native Nephrectomy in Autosomal Dominant Polycystic Kidney Disease Patients
M. Eltemamy, A. Crane, M. Elmer-Dewitt, B. Frainey, A. Elshafei, A. Wee, D. Goldfarb, V. Krishnamurthi.
Cleveland Clinic, Cleveland.
Introduction: 50% of autosomal dominant polycystic kidney disease (ADPKD) patients will develop ESRD. For those patients who undergo renal transplantation (RT) and require a native…
2018 American Transplant Congress
Tacrolimus Pharmacokinetics (PK) at Low, Medium, and High Trough Levels in Patients Converted from Twice-Daily Immediate-Release Tacrolimus (TacBID) to Once-Daily Extended-Release Tacrolimus (LCPT)
P. Malvezzi,¹ S. Bunnapradist,² D. Stevens,³ M. Moten,³ A. Loh,³ S. Patel,³ L. Rostaing.¹
¹Service De Néphrologie, Hémodialyse, Aphérèses Et Transplantation Rénale, Chu Grenoble Alpes, La Tronche, France; ²Nephrology, University of California, Los Angeles, Los Angeles, CA; ³Veloxis, Cary, NC.
LCPT (Envarsus XR®) is a once-daily, extended-release formulation of tacrolimus which has demonstrated greater bioavailability and a smoother PK profile compared to TacBID. This post-hoc…
2018 American Transplant Congress
The Providers Can't Let Go! An Analysis of an RN Driven Tacrolimus Dose Adjustment Protocol
Z. Elmaasarani, C. Mardis, L. Gylten, J. Fleming, H. Meadows, N. Patel, C. Perez, D. Taber, V. Rao, V. Rohan, P. Baliga, D. Dubay, N. Pilch.
MUSC, Charleston.
Introduction: Tacrolimus (FK) dose adjustment is frequently performed by non-MD staff. Standard protocols to evaluate the ability of non-providers to maintain pts within a goal…
2018 American Transplant Congress
Increasing Obesity Prevalence in the United States Pediatric End-Stage Renal Disease Population
B. Shelton,¹ P. MacLennan,¹ R. Reed,¹ M. Mustian,¹ D. McWilliams,¹ D. Sawinski,² J. Locke.¹
¹Surgery, University of Alabama at Birmingham, Birmingham, AL; ²Medicine, University of Pennsylvania, Philadelphia, PA.
Background: Obesity prevalence among children in the United States (US) is high, but the rate of increase has slowed over time. Among pediatric end-stage renal…
2018 American Transplant Congress
Krüppel-Like Factor 15 is a Key Suppressor of the Glomerular Epithelial Cell Fibrosis under Centrifugal Force Driven Pressure
M. Yu,¹ Y. Kim,¹ H. Lee,¹ J. Lee,² R. Cha,³ C. Lee,⁴ Y. Kim,¹ S. Yang.⁵
¹Seoul National University Hospital, Seoul, Korea; ²Seoul National University Boramae Medical Center, Seoul, Korea; ³National Medical Center, Seoul, Korea; ⁴Cheju Halla General Hospital, Jeju, Korea; ⁵Seoul National University Kidney Research Institue, Seoul, Korea.
Hypertension is known to be responsible for a reduction in the number of functional nephrons of glomeruli due to fibrosis, which develops into a chronic…
2018 American Transplant Congress
Liver Transplants from Older Donors Have Worse Outcomes in Elderly Recipients with Renal Dysfunction
R. Schilke,¹ M. Safwan,¹ S. Nagai,¹ M. Abouljoud,² A. Patel.¹
¹Transplant Institute, Henry Ford Health System, Detroit, MI; ²Nephrology, Henry Ford Health System, Detroit, MI.
Background: Most end stage liver disease patients suffer from concomitant renal insufficiency. We aimed to study influence of donor age on outcomes in elderly liver…
2018 American Transplant Congress
Comparison of Three Approaches for Laparoscopic Donor Nephrectomy: Transvaginal, Transumbilical Single Site and Retroperitoneal
M. Miura, H. Higashiyama.
Department of Urology and Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.
Objectives: Reduction of burdens to live kidney donors are important. The aim of this study was to compare the surgical outcomes of 3 approaches we…
2018 American Transplant Congress
National Study of Living Donor Program Protocols, Processes, and Resources within U.S. Transplant Centers
D. Moore,¹ M. Dietrich,¹ P. Buerhaus,² J. Rodrigue,³ A. Minnick.¹
¹Vanderbilt University, Nashville; ²Montana State University, Bonzeman; ³Beth Israel Deaconess MC, Boston.
Purpose: There is limited research that describes living donor (LD) program processes and protocols. This study aimed to describe LD program protocols, processes, and resources…
2018 American Transplant Congress
Endothelin A Receptor (ETaR) siRNA Ameliorates Renal Ischemia Reperfusion Injury through Upregulating Expression of eNOS in Rats
Y. Jia, L. Li, T. Zhu.
Shanghai Key Labratory of Organ Transplantation, Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Aims: To explore the protective effect of Endothelin A Receptor (ETaR) siRNA on renal ischemia reperfusion injury and its underlying mechanism.Methods: The model of unilateral…
2018 American Transplant Congress
Program-Specific Transplant Rate Ratios: Association with Allocation Priority at Listing and Posttransplant Outcomes
A. Wey, S. Gustafson, N. Salkowski, J. Pyke, B. Kasiske, A. Israni, J. Snyder.
SRTR, Mineapolis.
The Scientific Registry of Transplant Recipients (SRTR) has updated the transplant rate and waitlist mortality risk-adjustment models to include a wider range of candidate characteristics…