2019 American Transplant Congress
Racial Disparity in Pre-Kidney Transplant Work-Up
*Purpose: The purpose of this study was to evaluate the disparity, by race, for pre-kidney transplant work-up completion rates of referred patients.*Methods: We conducted a…2019 American Transplant Congress
Clazakizumab (CLZ, Anti-IL-6 Monoclonal Antibody) Treatment of Patients (Pts) with Chronic Antibody-Mediated Rejection (cABMR) Reduces Total Immunoglobulin (Ig) and Anti-HLA IgG Antibody Levels
Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: We have recently reported successful use of Tocilizumab (TCZ), an anti-IL-6 receptor (R) monoclonal antibody, for cABMR treatment in HLA-sensitized kidney transplant (KTx) Pts.…2019 American Transplant Congress
Intrinsic Organ Quality Assessment Using Integrative Short Outcome Prediction Composite Scores
*Purpose: Organs discards continue to be high due to lack of accurate tools to assess donor quality and predict organ function.To identify characteristics associated with…2019 American Transplant Congress
Qualitative Recovery Outcomes of Living Kidney Donors
*Purpose: The purpose of this study was to evaluate the qualitative outcomes of living kidney donors by gender.*Methods: We conducted a retrospective cohort study of…2019 American Transplant Congress
Clinical Importance of the Updated Oxford Classification in Allograft IgA Nephropathy
*Purpose: An additional investigation on the clinical significance of the updated Oxford classification in allograft IgA nephropathy (IgAN) is warranted.*Methods: We performed a retrospective cohort…2019 American Transplant Congress
Subclinical Rejection is Common on Surveillance Biopsies in Children with Kidney Transplant
*Purpose: Surveillance biopsies provide the opportunity to identify subclinical rejection and other pathologic changes, yet their utilization varies across pediatric kidney transplant centers. The purpose…2019 American Transplant Congress
Post-Transplant Lymphoproliferative Disorders in Pediatric Renal Transplant Recipients: Case Series of 5 Patients
*Purpose: Post-transplant Lymphoproliferative Disorders (PTLD) after solid organ transplantation is a complication of chronic immunosuppression (IS) and is generally associated with Epstein Barr virus (EBV)…2019 American Transplant Congress
Urine Recirculation Maintains Hemodynamics and Enhances Function in Normothermic Kidney Perfusion
*Purpose: The purpose was to compare urine recirculation (URC) and urine replacement with Ringer’s lactate in a porcine normothermic kidney perfusion (NKP) model using a…2019 American Transplant Congress
Minimizing Kidney Ischemia Reperfusion Injury by Transferring Exogenous Mitochondria
*Purpose: Ischemia induces altered bioenergetics with increased mitochondrial swelling and reactive oxygen species (ROS) and ultimately degradation of cellular function. Ischemia followed by reperfusion (IRI)…2019 American Transplant Congress
Using Ensembles of Machine Learning Classifiers to Maximize the Accuracy and Stability of Molecular Biopsy Interpretation
*Purpose: The Molecular Microscope diagnostic system (MMDx), based on microarray gene expression, uses ensembles of machine learning classifiers rather than single genes, gene sets, or…
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