Articles tagged "Kidney"

2019 American Transplant Congress
Early And Late Borderline Lesions Exhibit Differential Outcomes In Renal Transplant Recipients
N. K. Wilson¹, S. Tremblay¹, P. Lee¹, S. Bumb¹, R. R. Alloway¹, A. R. Shields², M. Cardi², E. S. Woodle¹
¹University of Cincinnati, Cincinnati, OH, ²The Christ Hospital, Cincinnati, OH
*Purpose: A major distinguishing factor in the risk of acute rejection episodes that markedly affects graft survival is the timing of the rejection episode. Early…
2019 American Transplant Congress
Immunosuppression Reduction after Diagnosis of Sustained BK Viremia and the Risk of Allograft Rejection, Allograft Loss and Mortality
F. A. Al Dhufairi¹, M. Shokoohi², A. M. Jevnikar¹, A. A. House¹, D. Kumar³, S. M. Hosseini-Moghaddam¹
¹Department of Medicine, Western University, London Health Sciences Centre, London, ON, Canada, ²Epidemiology and Biostatistics, Western University, London, ON, Canada, ³Department of Medicine, University Of Toronto, University Health Network, Toronto, ON, Canada
*Purpose: BK viremia increases the risk of allograft loss after renal transplantation. Current guidelines recommend immunosuppression reduction (IsR) after the diagnosis of BK viremia. The…
2019 American Transplant Congress
The Effect of the Beneficial Activity of α-Lipoic Acid Treatment Depend on the Quality of the Graft Kidneys
F. Osella¹, N. Ambrosi², G. Werber¹, F. Caro², S. Beltramino¹, I. Cabrera¹, G. Hilchenbach¹, L. Diaz Alvarez¹, C. Incardona³, E. Chuluyan², D. Casadei¹
¹Instituto de Trasplante y Alta Complejidad, Buenos Aires, Argentina, ²CEFYBO, UBA, Buenos Aires, Argentina, ³GADOR S.A., Buenos Aires, Argentina
*Purpose: In a previous preliminary study, with a small number of patients, we observed that the treatment of the donor and the recipient with the…
2019 American Transplant Congress
The Use of mTOR Inhibitors Prevents Acute Cellular Rejection in Kidney Transplantation on Belatacept Therapy
J. Shoji, J. C. Leung, Q. Tang, J. P. Roberts, F. Vincenti
University of California San Francisco, San Francisco, CA
*Purpose: Belatacept is a costimulatory blocker that is used as de novo maintenance immunosuppression in kidney transplantation to avoid toxic effects of calcineurin inhibitors and…
2019 American Transplant Congress
The More You Wait, the More You Lose: Prostatectomy and Kidney Transplant Waiting Time in End Stage Renal Disease
N. Sarabu¹, N. Schiltz², K. D. Chavin¹, D. E. Hricik¹
¹University Hospitals of Cleveland, Cleveland, OH, ²Case Western Researve University, Cleveland, OH
*Purpose: Optimal treatment and waiting time for patients with prostate cancer awaiting kidney transplant is unclear.*Methods: We studied male patients, 40 years or older, with…
2019 American Transplant Congress
Platelets Augment Granzyme K Production By Macrophages In Antibody-mediated Rejection
J. Dhar, K. Keslar, R. Fan, N. Dvorina, W. Baldwin
Cleveland Clinic Main Campus, Lerner Research Institute, Cleveland, OH
*Purpose: When antibodies bind to MHC antigens on endothelial cells a cascade of responses is initiated including exocytosis of adhesion molecules followed by attachment and…
2019 American Transplant Congress
Single Cell Analysis of Kidney Allograft Rejection
C. M. Castro-Rojas¹, K. M. Roskin², C. G. Moore², B. Abu Jawdeh³, N. Salomonis², R. R. Alloway⁴, E. Woodle⁴, D. A. Hildeman¹
¹Immunobiology, Cincinnati Children's Hospital, Cincinnati, OH, ²Biomedical Informatics, Cincinnati Children's Hospital, Cincinnati, OH, ³Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, ⁴Transplantation, University of Cincinnati College of Medicine, Cincinnati, OH
*Purpose: Rejection therapies (corticosteroids and antilymphocyte globulins) have not changed in over 50 years. In part this is due to a knowledge deficit of signaling…
2019 American Transplant Congress
Investigating Deceased Donor Kidney Discard Trend – An Opportunity To Expand The Donor Pool
J. A. Shah¹, D. P. Borle¹, K. Koontz², W. Irish¹, K. V. Ravindra¹
¹Abdominal Transplant Surgery, Duke University Medical Center, Durham, NC, ²Carolina Donor Services, Durham, NC
*Purpose: As the number of patients awaiting kidney transplantation increases from year to year, centers must maximize efforts to transplant kidneys procured. One way of…
2019 American Transplant Congress
Renal Allograft Survival after Dual Kidney Transplantation is at Least as Favorable as Outcome after Expanded Criteria Donor Kidney Transplantation
A. Brar¹, M. Sattar¹, A. Gruessner¹, R. M. Jindal², R. Nee³, R. Gruessner¹, M. Salifu¹
¹SUNY Downstate Medical Center, Brooklyn, NY, ²Department of Surgery,, USU-Walter Reed Uniformed Services University, Bethesda, MD, ³USU-Walter Reed Uniformed Services University, Bethesda, MD
*Purpose: Dual kidney transplantation (DKT) is the implantation of two adult kidneys from a marginal donor into a single recipient. DKT may play an important…
2019 American Transplant Congress
Sex, Race, Social Networks, and Requests for Living Donation
A. Gillespie¹, H. Gardiner², E. L. Fink³, P. P. Reese⁴, C. Gadegbeku¹, Z. Obradovic⁵
¹Nephrology, Hypertension, and Kidney Transplantation, Lewis Katz School of Medicine Temple Universiy, Philadelphia, PA, ²College of Public Health, Temple Universiy, Philadelphia, PA, ³Communication and Social influence, Temple University Klein College of Media and Communication, Philadelphia, PA, ⁴Renal-Electrolyte and Hypertension, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, ⁵College of Computer and Information Sciences, Temple Universiy, Philadelphia, PA
*Purpose: Little is known about the social networks of End Stage Renal Disease (ESRD) patients even though the members of these networks are most likely…