Articles tagged "Kidney"

2020 American Transplant Congress
Sex Differences in Transplant Decision-Making
A. Wasim¹, H. Rafiqzad¹, M. Dastgheib¹, H. Ford¹, S. Macanovic¹, K. Wernerowski¹, S. Aghamohammadi¹, M. Novak¹, A. D. Waterman², I. Mucsi¹
¹University Health Network, Toronto, ON, Canada, ²University of California, Los Angeles, Los Angeles, CA
*Purpose: We examined the relationship between sex and the relative importance of pros and cons in kidney transplant (KT) decision making.*Methods: A convenience sample of…
2020 American Transplant Congress
Combining New Biomarkers: Donor Derived Cell Free DNA (dd-cfDNA) and Transcriptomics Impacts Rejection Diagnosis, Treatment and Follow Up
S. Anand, L. Dong, D. Miller, I. Lloyd, D. Morris, T. Srinivas
Intermountain Medical Center, Murray, UT
*Purpose: Transcriptomics (Tr) is an emerging adjunct to traditional histological diagnosis (HDx) for kidney allograft rejection (KAR). We describe our experience of using Tr and…
2020 American Transplant Congress
The Effect of Desensitization Therapy on Sex Disparity in Living Kidney Transplantation
Y. Kakuta¹, M. Okumi¹, T. Kanzawa¹, K. Unagami², H. Ishida², K. Tanabe¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan, ²Organ Transplant Medicine, Tokyo Women's Medical University, Tokyo, Japan
*Purpose: Sex- and gender-based disparities which have shown women to have lower access to kidney transplantation have been reported. In living kidney transplantation (LKT), pregnancy-related…
2020 American Transplant Congress
Diagnostic Method of Acute Kidney Rejection after Transplantation Using Metabolome Analysis via a Liquid Biopsy Approach
H. Iwamoto
Department of Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan
*Purpose: At present, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy…
2020 American Transplant Congress
Quantifying the Number of ESRD Patients Who Might Benefit from Bariatric Surgery to Achieve Listing for Transplant
B. Orandi¹, P. MacLennan¹, S. Mehta¹, J. Grams¹, R. Stahl¹, R. Cannon¹, D. Anderson¹, M. Hanaway¹, C. Young¹, J. Purvis¹, N. Terrault², C. Lewis¹, J. Locke¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Southern California, Los Angeles, CA
*Purpose: Mounting evidence suggests bariatric surgery may play a role in helping obese ESRD patients achieve sufficient weight loss to be transplant-eligible. We sought to…
2020 American Transplant Congress
Hematopoietic Cell Kinase Promotes Kidney Fibrosis Through Autophagy Pathway
C. Wei, L. Mou, K. Banu, M. Menon, W. Zhang, C. He, B. Murphy
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: In our previous studies, we identified hematopoietic cell kinase (HCK) as a key driver of renal fibrosis through TGFβ/Smad3 pathway. Here in this study,…
2020 American Transplant Congress
Post- Transplant Recurrence of IgA Nephropathy: HLA as a Predictive Factor
C. R. Kavanagh¹, N. G. Jain¹, R. Vasilescu², J. Kamal³, I. Batal²
¹Pediatric Nephrology, Columbia University Medical Center, New York, NY, ²Pathology, Columbia University Medical Center, New York, NY, ³Surgery, Columbia University Medical Center, New York, NY
*Purpose: Genomic studies have identified several HLA antigens to be associated with IgA Nephropathy in the native kidney. In contrast to the native kidney, there…
2020 American Transplant Congress
Safety of Belatacept in HIV-Positive Kidney Transplant Recipients
K. El Sakhawi¹, A. Scemla², D. Bertrand³, C. Garrouste⁴, P. Malvezzi⁵, P. Grimbert¹, M. Matignon¹
¹Nephrology, APHP Henri Mondor, Créteil, France, ²Nephrology, APHP Necker Enfants Malades, Paris, France, ³Nephrology, CHU Bois Guillaume, Rouen, France, ⁴Nephrology, CHU Clermond Ferrand, Clermont Ferrand, France, ⁵Nephrology, CHU Grenoble, Grenoble, France
*Purpose: Kidney allograft survival in HIV-infected patients is lower than in the general population. Belatacept (instead of anticalcineurins (CNI)) has been shown to have a…
2020 American Transplant Congress
Identifying Factors Associated with Delayed Graft Function Severity Using the OPTN Database
K. Checchi¹, D. Stewart², A. Toll², J. Case¹, S. Kurian¹, C. Marsh¹
¹Scripps Health, La Jolla, CA, ²United Network for Organ Sharing Research Department, Richmond, VA
*Purpose: Delayed graft function (DGF) is a costly adverse outcome in kidney transplantation with negative implications for both graft and patient survival. Identifying factors associated…
2020 American Transplant Congress
Reverse Epidemiology and the Obesity Paradox for Patients with Chronic Kidney Disease
R. A. Choudhury¹, D. Yoeli¹, H. B. Moore¹, H. Yaffe¹, G. Hoeltzel², K. R. Dumon³, N. N. Williams³, P. L. Abt⁴, K. D. Conzen¹, T. L. Nydam¹
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Thomas Jefferson University Hospital, Philadelphia, PA, ³University of Pennsylvania Hospital, Philadelphia, PA, ⁴Department of Surgery- Division of Transplantation Surgery, University of Pennsylvania Hospital, Philadelphia, PA
*Purpose: Obesity has been associated with both increased progression of chronic kidney disease as well as with a paradoxical improvement in survival among ESRD patients…