Articles tagged "Kidney"

2020 American Transplant Congress
BAFF Inhibition to Prevent Antibody Rebound Following Proteasome Inhibitor-Based Desensitization: A Randomized, Controlled Trial
S. Tremblay¹, A. Rike-Shields², A. Govil¹, M. Cardi³, P. Brailey¹, R. Alloway¹, E. Woodle¹
¹U Cincinnati, Cincinnati, OH, ²Surgery, U Cincinnati, Christ Hospital, Cincinnati, OH, ³Christ Hospital, Cincinnati, OH
*Purpose: Proteasome inhibitor (PI) therapy reduces bone marrow plasma cells and HLA antibodies (Abs) in renal transplant candidates. However, rebound is common in many patients…
2020 American Transplant Congress
Transition from Youth to Adult Care of Kidney Transplant Recipients: Single Center Experience
L. Ganesan, A. McGrath, K. Dahl, K. Dinello, A. Fong, L. Maestretti, M. Patton, P. Grimm, A. Chaudhuri
Pediatric Nephrology, Lucile Packard Children's Hospital, Stanford, CA
*Purpose: Transition of transplant recipients from youth to adult care has been a challenge for many. Starting in March 2017, Lucile Packard Children’s Hospital (LPCH)…
2020 American Transplant Congress
Torque Teno Virus Level for Risk Stratification of Subclinical Graft Rejection at 12 Months after Kidney Transplantation – An Prospective Observational Cohort Study
K. Doberer, E. Puchhammer, G. Böhmig, G. Bond
Medical University Vienna, Vienna, Austria
*Purpose: Non-invasive monitoring strategies are insufficient to detect patients at risk for subclinical graft rejection after kidney transplantation. The highly prevalent and non-pathogenic Torque Teno…
2020 American Transplant Congress
Serum αKlotho after Living Kidney Donation: A Systematic Review and Meta-Analysis
W. Cheungpasitporn¹, C. Thongprayoon², N. Leeaphorn³, M. A. Mao⁴, J. A. Neyra⁵
¹Nephrology, University of Mississippi Medical Center, Jackson, MS, ²Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ³Renal Transplant Program, University of Missouri-Kansas City School of Medicine/Saint Luke's Health System, Kansas City, MO, ⁴Nephrology and Hypertension, Mayo Clinic, Jacksonville, FL, ⁵Nephrology, University of Kentucky, Lexington, KY
*Purpose: αKlotho (klotho) is a known anti-aging protein that exerts diverse physiological effects. Defect in klotho gene expression in mice can result in a syndrome…
2020 American Transplant Congress
Mesenchymal Stromal Cell Treatment of Kidneys During Normothermic Machine Perfusion is Safe and Feasible with Effective Traceability after Transplantation
K. Rozenberg¹, S. Lohmann², M. Pool³, M. Eijken⁴, U. Møldrup⁵, B. Møller⁶, J. Sierra-Parraga⁷, M. Hoogduijn⁷, L. Lo Faro¹, C. Moers³, J. Hunter¹, A. Keller², H. Leuvenink³, C. Baan⁷, R. Ploeg¹, B. Jespersen²
¹Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, ²Department of Clinical Medicine, Aarhus University, Aarhus, Denmark, ³Department of Surgery, University Medical Center Groningen, Groningen, Netherlands, ⁴Department of Renal Medicine, Aarhus University, Aarhus, Denmark, ⁵Department of Urology, Aarhus University, Aarhus, Denmark, ⁶Department of Clinical Immunology, Aarhus University, Aarhus, Denmark, ⁷Department of Internal Medicine, Nephrology and Transplantation, Erasmus MC, University Medical Center, Rotterdam, Netherlands
*Purpose: Marginal kidneys are increasingly being accepted to decrease waiting time for a transplant. Normothermic machine perfusion (NMP) is a technique that allows delivery of…
2020 American Transplant Congress
“By the Time They Get to Me, I’ll Be Dead Anyway” – A Mixed-Methods Examination of Treatment Education & Decision-Making among Patients with Varying Amounts of Pre-End-Stage Renal Disease Nephrology Care
M. Urbanski¹, L. Dumenci¹, C. Gadegbeku², L. Siminoff¹, A. Waterman³, H. Gardiner¹
¹College of Public Health, Temple University, Philadelphia, PA, ²Lewis Katz School of Medicine, Section of Nephrology, Hypertension, and Kidney Transplantation, Temple University, Philadelphia, PA, ³UCLA, Division of Nephrology, Los Angeles, CA
*Purpose: The aim of this study was to explore renal replacement therapy (RRT) knowledge and decision-making experiences and preferences among patients with varying amounts of…
2020 American Transplant Congress
Clinical Performance of a Donor-Derived Cell-Free DNA Assay for Detection of Rejection in Kidney Transplant Recipients
S. Kleiboeker, J. Grantham, K. Mickey, S. Cowden, E. Bixler, R. Sinha, M. Altrich
Viracor Eurofins, Lees Summit, MO
*Purpose: Rejection is a major complication in solid organ transplant recipients and diagnosis often depends on periodic invasive biopsies. Thus there is a need for…
2020 American Transplant Congress
Association between Response to Rituximab and Risk of Antibody-Mediated Rejection in ABO-Incompatible Living Kidney Transplantation
Y. Kakuta¹, M. Okumi¹, T. Kanzawa¹, K. Unagami², H. Ishida², K. Tanabe¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan, ²Organ Transplant Regulation, Tokyo Women's Medical University, Tokyo, Japan
*Purpose: Owing to limited organ availability, ABO-incompatible living kidney transplantation (ABO-ILKT) has been used extensively. Various forms of preconditioning therapies have been used alone or…
2020 American Transplant Congress
Poly (ADP-Ribose) Polymerase Inhibitor Treatment Attenuated Renal Ischemia-Reperfusion Injury
H. Jang, K. Lee, J. Jeon, J. Lee, Y. Kim, D. Kim, W. Huh
Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of
*Purpose: Robust intrarenal inflammatory responses following ischemia-reperfusion injury (IRI) induce renal injury in ischemic acute kidney injury (AKI). We hypothesized that poly (ADP-Ribose) polymerase (PARP)…
2020 American Transplant Congress
Parathyroidectomy Remains Effective for Treating Tertiary Hyperparathyroidism: Long-Term Results of a Randomized Study
A. Coloma¹, P. Moreno², J. Torregrosa³, N. Montero¹, A. Manonelles¹, E. Melilli¹, J. Cruzado¹
¹Nephrology, Hospital Universitari de Bellvitge, Hospitalet de LLobregat, Spain, ²Surgery, Hospital Universitari de Bellvitge, Hospitalet de LLobregat, Spain, ³Nephrology, Hospital Clinic, Barcelona, Spain
*Purpose: Tertiary hyperparathyroidism is a common cause of hypercalcemia after kidney transplant (KT). The aim of this study is to evaluate the long-term effectiveness of…