Articles tagged "Kidney"

2022 American Transplant Congress
Single Center Assessment of Completing Kidney Evaluations: Race and Ethnicity Were Not Predictors for Preemptive Kidney Transplant Patients
T. Menser, M. J. Hobeika, E. Hsu, L. W. Moore, A. D. Waterman, A. O. Gaber, R. J. Knight
Houston Methodist, Houston, TX
*Purpose: This study examines the differential progress from beginning the transplant evaluation process to its completion and subsequent presentation to the Candidate Selection Committee (CSC)…
2022 American Transplant Congress
Donor Black Race Modifies the Association Between Increasing Donor Age and Graft Failure Following Living Kidney Transplantation
K. Atiemo, R. Baudier, A. Anderson
Tulane University, New Orleans, LA
*Purpose: Transplantation utilizing Black living donor kidneys is associated with poorer outcomes.A possible explanation is genetic(APOL1). Kidneys from healthy older Black donors are considered lower…
2022 American Transplant Congress
The US Kidney Allocation System Should Not Allocate En Bloc Kidneys from Deceased Donors < 18 Kg as Equivalent to Top 20% KDPI Single Kidneys
W. F. Parker¹, A. Gallo², L. Ross¹
¹University of Chicago, Chicago, IL, ²Stanford University, Palo Alto, CA
*Purpose: In December 2020, the US Kidney Allocation System (KAS) revised the allocation rules for deceased donors under 18 kg, stating that both kidneys must…
2022 American Transplant Congress
Evaluation of the Significance of Isolated C4d Staining without Histological Evidence of Rejection on Kidney Biopsies After ABO-Compatible Transplantation in Pediatric Recipients
C. Duneton¹, M. Rabant², J. Duong-Van-Huyen², V. Baudouin¹, E. Cheyssac¹, O. Boyer³, J. Hogan¹
¹Pediatric Nephrology, Robert Debré Hospital, APHP, Paris, France, ²Pathology, Necker Hospital, Paris, France, ³Pediatric Nephrology, Necker Hospital, Paris, France
*Purpose: C4d staining in peritubular capillaries has been part of ABMR Banff definition since 2003. Despite relatively high specificity, c4d staining shows limited sensitivity, and…
2022 American Transplant Congress
Validation of a Hypertension Risk Calculator for Living Kidney Donors
E. S. Helgeson¹, S. Vempati¹, E. F. Palzer¹, G. Mjøen², A. J. Haugen³, A. Matas⁴
¹Division of Biostatistics, University of Minnesota, Minneapolis, MN, ²Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway, ³Department of Internal Medicine, Bærum Hospital, Sandvika, Norway, ⁴Department of Surgery, University of Minnesota, Minneapolis, MN
*Purpose: It would be ideal if candidates considering kidney donation understood their long-term risks. Using single-center data (n=4055; median [IQR] f/u: 18 [9-28] yrs), we…
2022 American Transplant Congress
Telemedicine Services for Living Kidney Donation: A U.S. Survey of Multidisciplinary Providers
F. Al Ammary¹, J. Motter¹, H. Sung¹, K. Lentine², A. Sharfuddin³, V. Kumar⁴, A. Yadav⁵, M. Doshi⁶, S. Virmani⁷, B. Concepcion⁸, T. Grace⁹, C. Sidoti¹, M. Y. Jon³, A. Muzaale¹, J. Wolf¹⁰
¹Johns Hopkins, Baltimore, MD, ²Saint Louis University, St. Louis, MO, ³Indiana University, Indianapolis, IN, ⁴University of Alabama, Birmingham, AL, ⁵Thomas Jefferson, Philadelphia, MD, ⁶University of Michigan, Ann Arbor, MD, ⁷Yale, New Haven, CT, ⁸Vanderbilt, Nashville, TN, ⁹Wake Forest, Winston-Salem, NC, ¹⁰Piedmont, Atlanta, GA
*Purpose: Individuals considering living kidney donation face geographic, financial, and logistical challenges. Telemedicine has the potential to facilitate care delivery/coordination for donors. We aimed to…
2022 American Transplant Congress
Donor Kidneys from Communities with Higher Deprivation Are Significantly More Likely to be Discarded
J. Schold¹, A. Huml¹, E. Poggio¹, E. Dewey¹, R. Buchalter¹, S. Husain², S. Mohan²
¹Cleveland Clinic, Cleveland, OH, ²Columbia University, New York, NY
*Purpose: The proportion of kidneys procured for the purpose of transplantation but ultimately discarded exceeds 20% in the US. Factors associated with deceased donor kidney…
2022 American Transplant Congress
Personalized Medicine Using Next-Generation Sequence for Kidney Transplant Recipients
J. Sanchez-Garcia, D. Morris, E. Darling, M. Dantis-Tan, J. Olson, K. Gaid, A. Raza, S. Anand
Intermountain Medical Center, Murray, UT
*Purpose: Tissue diagnosis definitely drives therapeutic and prognostic decisions amongst patients with chronic kidney disease (CKD). However, patients with CKD often present late in the…
2022 American Transplant Congress
Membrane Attack Complex as a More Sensitive Tool to Evaluate Complement Activation in Kidney Transplant Recipients with Donor-Specific Antibodies
C. Arias-Cabrales, D. Redondo-Pachón, E. Rodríguez, M. Riera, A. Buxeda, M. Pérez-Sáez, C. Burballa, L. Llinas, J. Pascual, M. Crespo
Nephrology, Hospital del Mar, Barcelona, Spain
*Purpose: Kidney transplant recipients with late HLA donor-specific antibodies (DSA) detected with single antigen beads (SAB) exhibit more frequent antibody-mediated rejection (ABMR) and graft loss.…
2022 American Transplant Congress
Proteome Profiling of Recurrent Primary Focal Segmental Glomerulosclerosis (FSGS) Plasma Samples Reveals Potential Proteins Involved in Primary FSGS
L. Gallon¹, N. Ahsan², V. Mas³, J. Leventhal¹, L. Fornelli²
¹Northwestern Univ NMFF, Chicago, IL, ²Mass Spectrometry, Proteomics and Metabolomics Core Facility, Department of Chemistry and Biochemistry, The University of Oklahoma, Oklahoma, OK, ³University of Maryland, Baltimore, MD
*Purpose: The presumed etiology of primary FSGS is a plasma factor that results in general podocyte dysfunction with partial and/or unpredictable response to immunosuppressive therapy…